STUDENT C O M P A N I O N
F U N D A M
U
E N T A L S O F
Biochemistry
LIFE AT U
THE MOLECULAR
U U
LEVEL
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman
U Jerry Johnson Joseph Eichberg
U U
William WidgerDonald Voet
U U U
Judith G. Voet
U Charlotte W. Pratt
U U U
,ThisUpageUisUintentionallyUleftUblank
,STUDENT COMPANION TO ACCOMPANY
FUNDAMENTALS OF
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Fourth Edition
Akif Uzman
U
University of Houston
U U
Jerry Johnson
U
University of Houston
U U
Joseph Eichberg U
University of Houston
U U
William Widger U
University of Houston
U U
Donald Voet U
University of Pennsylvania
U U
Judith G. Voet
U U
Swarthmore College U
Charlotte W. Pratt U U
Seattle, Washington
U
JOHNUWILEYU&USONS,UINC
, CoverUDesignerUMadelynULesureUCo
verUIllustrationUNormUChristiansenUC
overUPhotos
(VitruvianUMan):U©UOdysseus/AlamyUandU©UDennisUHallinan/Alamy
MolecularUstructuresUclockwiseUfromUtop:UbasedUonUX-
rayUstructuresUthatUwereUrespectivelyUdeterminedUbyURichardUDickersonUandUHoraceUDrew,UCaltech;UG
erardUBunick,UUniversityUofUTennessee;UThomasUSteitz,UYaleUUniversity;UAlfonsoUMondragón,UNorthw
esternUUniversity;UVenkiURamakrishnan,UMRCULaboratoryUofUMolecularUBiology,UCambridge,UU.K.;UA
ndrewULeslieUandUJohnUWalker,UMRCULaboratoryUofUMolecularUBiology,UCambridge,UU.K.
FoundedUinU1807,UJohnUWileyU&USons,UInc.UhasUbeenUaUvaluedUsourceUofUknowledgeUandUunderstandingU
forUmoreUthanU200Uyears,UhelpingUpeopleUaroundUtheUworldUmeetUtheirUneedsUandUfulfillUtheirUaspirations.
UOur UcompanyUisUbuiltUonUaUfoundationUofUprinciplesUthatUincludeUresponsibilityUtoUtheUcommunitiesUweUs
erveUandUwhereUweUliveUandUwork.UInU2008,UweUlaunchedUaUCorporateUCitizenshipUInitiative,UaUglobalUeff
ortUtoUaddressUtheUenvironmental,Usocial,Ueconomic,UandUethicalUchallengesUweUfaceUinUourUbusiness.UAm
ongUtheUissuesUweUareUaddressingUareUcarbonUimpact,UpaperUspecificationsUandUprocurement,UethicalUcond
uctUwithinUourUbusinessUandUamongUourUvendors,UandUcommunityUandUcharitableUsupport.UForUmoreUinfor
mation,UpleaseUvisitUourUwebsite:Uwww.wiley.com/go/citizenship.
CopyrightU©U2012 JohnUWileyU&USons,UInc.
AllUrightsUreserved.UNoUpartUofUthisUpublicationUmayUbeUreproduced,UstoredUinUaUretrievalUsystemUorUtran
smittedUinUanyUformUorUbyUanyUmeans,Uelectronic,Umechanical,Uphotocopying,Urecording,UscanningUorUot
herwise,UexceptUasUpermittedUunderUSectionsU107UorU108UofUtheU1976UUnitedUStatesUCopyrightUAct,Uwit
houtUeitherUtheUpriorUwrittenUpermissionUofUtheUPublisher,UorUauthorizationUthroughUpaymentUofUtheUappr
opriateUper-
copyUfeeUtoUtheUCopyrightUClearanceUCenter,UInc.,U222URosewoodUDrive,UDanvers,UMAU01923,Uwebsite
Uwww.copyright.com.URequestsUtoUtheUPublisherUforUpermissionUshouldUbeUaddressedUtoUtheU Permissions
UDepartment,UJohnUWileyU&USons,UInc.U111URiverUStreet,UHoboken,UNJ U07030-5774,U(201)U748-
6011,UfaxU(201)U748-6008,UwebsiteUhttp://www.wiley.com/go/permissions.
ToUorderUbooksUorUforUcustomerUservice,UpleaseUcallU1-800-CALLUWILEYU(225-5945).
StudentUCompanionU(paperback) ISBN-13U 978-1-1182-1827-3
PrintedUinUtheUUnitedUStatesUofUAmeri
caU10U 9U8U7U 6U5U4U 3U2U1
F U N D A M
U
E N T A L S O F
Biochemistry
LIFE AT U
THE MOLECULAR
U U
LEVEL
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman
U Jerry Johnson Joseph Eichberg
U U
William WidgerDonald Voet
U U U
Judith G. Voet
U Charlotte W. Pratt
U U U
,ThisUpageUisUintentionallyUleftUblank
,STUDENT COMPANION TO ACCOMPANY
FUNDAMENTALS OF
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
Fourth Edition
Akif Uzman
U
University of Houston
U U
Jerry Johnson
U
University of Houston
U U
Joseph Eichberg U
University of Houston
U U
William Widger U
University of Houston
U U
Donald Voet U
University of Pennsylvania
U U
Judith G. Voet
U U
Swarthmore College U
Charlotte W. Pratt U U
Seattle, Washington
U
JOHNUWILEYU&USONS,UINC
, CoverUDesignerUMadelynULesureUCo
verUIllustrationUNormUChristiansenUC
overUPhotos
(VitruvianUMan):U©UOdysseus/AlamyUandU©UDennisUHallinan/Alamy
MolecularUstructuresUclockwiseUfromUtop:UbasedUonUX-
rayUstructuresUthatUwereUrespectivelyUdeterminedUbyURichardUDickersonUandUHoraceUDrew,UCaltech;UG
erardUBunick,UUniversityUofUTennessee;UThomasUSteitz,UYaleUUniversity;UAlfonsoUMondragón,UNorthw
esternUUniversity;UVenkiURamakrishnan,UMRCULaboratoryUofUMolecularUBiology,UCambridge,UU.K.;UA
ndrewULeslieUandUJohnUWalker,UMRCULaboratoryUofUMolecularUBiology,UCambridge,UU.K.
FoundedUinU1807,UJohnUWileyU&USons,UInc.UhasUbeenUaUvaluedUsourceUofUknowledgeUandUunderstandingU
forUmoreUthanU200Uyears,UhelpingUpeopleUaroundUtheUworldUmeetUtheirUneedsUandUfulfillUtheirUaspirations.
UOur UcompanyUisUbuiltUonUaUfoundationUofUprinciplesUthatUincludeUresponsibilityUtoUtheUcommunitiesUweUs
erveUandUwhereUweUliveUandUwork.UInU2008,UweUlaunchedUaUCorporateUCitizenshipUInitiative,UaUglobalUeff
ortUtoUaddressUtheUenvironmental,Usocial,Ueconomic,UandUethicalUchallengesUweUfaceUinUourUbusiness.UAm
ongUtheUissuesUweUareUaddressingUareUcarbonUimpact,UpaperUspecificationsUandUprocurement,UethicalUcond
uctUwithinUourUbusinessUandUamongUourUvendors,UandUcommunityUandUcharitableUsupport.UForUmoreUinfor
mation,UpleaseUvisitUourUwebsite:Uwww.wiley.com/go/citizenship.
CopyrightU©U2012 JohnUWileyU&USons,UInc.
AllUrightsUreserved.UNoUpartUofUthisUpublicationUmayUbeUreproduced,UstoredUinUaUretrievalUsystemUorUtran
smittedUinUanyUformUorUbyUanyUmeans,Uelectronic,Umechanical,Uphotocopying,Urecording,UscanningUorUot
herwise,UexceptUasUpermittedUunderUSectionsU107UorU108UofUtheU1976UUnitedUStatesUCopyrightUAct,Uwit
houtUeitherUtheUpriorUwrittenUpermissionUofUtheUPublisher,UorUauthorizationUthroughUpaymentUofUtheUappr
opriateUper-
copyUfeeUtoUtheUCopyrightUClearanceUCenter,UInc.,U222URosewoodUDrive,UDanvers,UMAU01923,Uwebsite
Uwww.copyright.com.URequestsUtoUtheUPublisherUforUpermissionUshouldUbeUaddressedUtoUtheU Permissions
UDepartment,UJohnUWileyU&USons,UInc.U111URiverUStreet,UHoboken,UNJ U07030-5774,U(201)U748-
6011,UfaxU(201)U748-6008,UwebsiteUhttp://www.wiley.com/go/permissions.
ToUorderUbooksUorUforUcustomerUservice,UpleaseUcallU1-800-CALLUWILEYU(225-5945).
StudentUCompanionU(paperback) ISBN-13U 978-1-1182-1827-3
PrintedUinUtheUUnitedUStatesUofUAmeri
caU10U 9U8U7U 6U5U4U 3U2U1
