Pharma Week 3 With Correct Answers 100% Verified!!
Pharmacokinetics - ANSWER The movement of the drug from entry to exit and what the
body does to it.
Pharmacodynamics - ANSWER What the drug does to the body.
ADME - ANSWER Refers to the 4 processes of pharmacokinetics: Absorption,
Distribution, Metabolism, Excretion.
Routes of Administration - ANSWER The two major routes are Enteral and parenteral.
Enteral Routes - ANSWER Three enteral routes are Oral, Sublingual, Rectal.
Parenteral Routes - ANSWER The three parenteral routes are IV, IM, Subcutaneous.
Bioavailability - ANSWER The amount of drug that reaches the systemic circulation
intact.
Drug Movement Across Plasma Membrane - ANSWER Drugs move via diffusion or
active transport.
Factors Related to the Drug Affecting Absorption - ANSWER Concentration, Chemical
nature, Particle size, Dissolution level.
Factors Related to the Body Affecting Absorption - ANSWER Surface area, pH of
stomach, Route of administration, Other diseases present.
, Distribution: Pharmacokinetics - ANSWER Passage of the agent through blood or
lymph to various body sites.
Factors Affecting Drug Distribution - ANSWER Blood flow, Capillary Permeability, Drug
structure, Binding to plasma proteins.
Drugs Bound to Plasma Proteins - ANSWER Drugs that are bounded are considered
inactive; only free drugs unbounded are effective.
Hydrophobic Drugs and Albumin Binding - ANSWER Hydrophobic drugs bind the
strongest to albumin (plasma protein).
Hydrophilic and Neutral Drugs and Albumin Binding - ANSWER Hydrophilic and neutral
drugs bind the weakest to albumin (plasma protein).
Class 1 and Class 2 Drugs - ANSWER Class 1 has more binding sites than available
dosage; Class 2 has more of the dose than existing binding sites.
Unbounded vs Bounded Drugs - ANSWER Unbounded drugs can express their effects
on the body; bounded drugs are inactive.
Metabolism in Pharmacokinetics - ANSWER The first-pass effect occurs when drugs
are taken orally and partially metabolized in the liver.
Hepatic Portal Circulation - ANSWER Carries blood from the GI tract to the liver.
Phase 1 and Phase 2 Reactions - ANSWER Phase 1 reactions modify the chemical by
adding a functional structure; Phase 2 conjugates it with another substance.
Conjugation - ANSWER A process in the liver that chemically modifies a drug or
substance, making it more water-soluble.
Pharmacokinetics - ANSWER The movement of the drug from entry to exit and what the
body does to it.
Pharmacodynamics - ANSWER What the drug does to the body.
ADME - ANSWER Refers to the 4 processes of pharmacokinetics: Absorption,
Distribution, Metabolism, Excretion.
Routes of Administration - ANSWER The two major routes are Enteral and parenteral.
Enteral Routes - ANSWER Three enteral routes are Oral, Sublingual, Rectal.
Parenteral Routes - ANSWER The three parenteral routes are IV, IM, Subcutaneous.
Bioavailability - ANSWER The amount of drug that reaches the systemic circulation
intact.
Drug Movement Across Plasma Membrane - ANSWER Drugs move via diffusion or
active transport.
Factors Related to the Drug Affecting Absorption - ANSWER Concentration, Chemical
nature, Particle size, Dissolution level.
Factors Related to the Body Affecting Absorption - ANSWER Surface area, pH of
stomach, Route of administration, Other diseases present.
, Distribution: Pharmacokinetics - ANSWER Passage of the agent through blood or
lymph to various body sites.
Factors Affecting Drug Distribution - ANSWER Blood flow, Capillary Permeability, Drug
structure, Binding to plasma proteins.
Drugs Bound to Plasma Proteins - ANSWER Drugs that are bounded are considered
inactive; only free drugs unbounded are effective.
Hydrophobic Drugs and Albumin Binding - ANSWER Hydrophobic drugs bind the
strongest to albumin (plasma protein).
Hydrophilic and Neutral Drugs and Albumin Binding - ANSWER Hydrophilic and neutral
drugs bind the weakest to albumin (plasma protein).
Class 1 and Class 2 Drugs - ANSWER Class 1 has more binding sites than available
dosage; Class 2 has more of the dose than existing binding sites.
Unbounded vs Bounded Drugs - ANSWER Unbounded drugs can express their effects
on the body; bounded drugs are inactive.
Metabolism in Pharmacokinetics - ANSWER The first-pass effect occurs when drugs
are taken orally and partially metabolized in the liver.
Hepatic Portal Circulation - ANSWER Carries blood from the GI tract to the liver.
Phase 1 and Phase 2 Reactions - ANSWER Phase 1 reactions modify the chemical by
adding a functional structure; Phase 2 conjugates it with another substance.
Conjugation - ANSWER A process in the liver that chemically modifies a drug or
substance, making it more water-soluble.
