Test Bank
Pathophysiology
(Author: Mccance) 8th Edition
,Table Of Contents
Part 1: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES
Unit I: THE CELL
1. Cellular Biology
2. Altered Cellular And Tissue Biology: Environmental Agents
3. The Cellular Environment: Fluids And Electrolytes, Acids And Bases
Unit II: GENES AND GENE-ENVIRONMENT INTERACTION
4. Genes And Genetic Diseases
5. Genes, Environment-Lifestyle, And Common Diseases
6. Epigenetics And Disease
Unit III: MECHANISMS OF SELF-DEFENSE
7. Innate Immunity: Inflammation
8. Adaptive Immunity
9. Alterations In Immunity And Inflammation
10. Infection
11. Stress And Disease
Unit IV. CELLULAR PROLIFERATION: CANCER
12. Cancer Biology
13. Cancer Epidemiology
14. Cancer In Children
Part 2: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS
Unit V: THE NEUROLOGIC SYSTEM
15. Structure And Function Of The Neurologic System
16. Pain, Temperature Regulation, Sleep, And Sensory Function
17. Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function
18. Disorders Of The Central And Peripheral Nervous Systems And The Neuromuscular Junction
19. Neurobiology Of Schizophrenia, Mood Disorders, And Anxiety Disorders
20. Alterations Of Neurologic Function In Children
Unit VI: THE ENDOCRINE SYSTEM
21. Mechanisms Of Hormonal Regulation
22. Alterations Of Hormonal Regulation
23. Obesity And Disorders Of Nutrition NEW
,Unit VII: THE REPRODUCTIVE SYSTEMS
24. Structure And Function Of The Reproductive Systems
25. Alterations Of The Female Reproductive System
26. Alterations Of The Male Reproductive System
27. Sexually Transmitted Infections
Unit VIII: THE HEMATOLOGIC SYSTEM
28. Structure And Function Of The Hematologic System
29. Alterations Of Erythrocyte, Platelet, And Hemostatic Function
30. Alterations Of Leukocyte And Lymphoid Function
31. Alterations Of Hematologic Function In Children
Unit IX: THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS
32. Structure And Function Of The Cardiovascular And Lymphatic Systems
33. Alterations Of Cardiovascular Function
34. Alterations Of Cardiovascular Function In Children
Unit X: THE PULMONARY SYSTEM
35. Structure And Function Of The Pulmonary System
36. Alterations Of Pulmonary Function
37. Alterations Of Pulmonary Function In Children
Unit XI: THE RENAL AND UROLOGIC SYSTEMS
38. Structure And Function Of The Renal And Urologic Systems
39. Alterations Of Renal And Urinary Function
40. Alterations Of Renal And Urinary Tract Function In Children
Unit XII: THE DIGESTIVE SYSTEM
41. Structure And Function Of The Digestive System
42. Alterations Of Digestive Function
43. Alterations Of Digestive Function In Children
Unit XIII: THE MUSCULOSKELETAL SYSTEM
44. Structure And Function Of The Musculoskeletal System
45. Alterations Of Musculoskeletal Function
46. Alterations Of Musculoskeletal Function In Children
Unit XIV: THE INTEGUMENTARY SYSTEM
47. Structure, Function, And Disorders Of The Integument
,48. Alterations Of The Integument In Children
Unit XV: MULTIPLE INTERACTING SYSTEMS
49. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Adults
50. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Children
,Chapter 1: Cellular Biology
MULTIPLE CHOICE
1. Which Statement Best Describes The Cellular Function Of Metabolic Absorption?
a. Cells Can Produce Proteins. C. Cells Can Take In And Use Nutrients.
b. Cells Can Secrete Digestive Enzymes. D. Cells Can Synthesize Fats.
ANS: C
In Metabolic Absorption, All Cells Take In And Use Nutrients And Other Substances From
Their Surroundings. The Remaining Options Are Not Inclusive In Their Descriptions Of
Cellular Metabolic Absorption.
PTS: 1 REF: Page 2
2. Most Of A Cell’s Genetic Information, Including RNA And DNA, Is Contained In The:
a. Mitochondria C. Nucleolus
b. Ribosome D. Lysosome
ANS: C
The Nucleus Contains The Nucleolus, A Small Dense Structure Composed Largely Of
RNA, Most Of The Cellular DNA, And The DNA-Binding Proteins, Such As The
Histones, Which Regulate Its Activity. The Other Options Do Not Contain Most Of A
Cell’s Genetic Information.
PTS: 1 REF: Page 2
3. Which Component Of The Cell Prodnuuc erssihnygd rt obg. Ceno m
peroxide (H2O2) By Using Oxygen
To Remove Hydrogen Atoms From Specific Substrates In An Oxidative Reaction?
a. Lysosomes C. Ribosomes
b. Peroxisomes D. Oxyhydrosomes
ANS: B
Peroxisomes Are So Named Because They Usually Contain Enzymes That Use Oxygen
To Remove Hydrogen Atoms From Specific Substrates In An Oxidative Reaction That
Produces H2O2, Which Is A Powerful Oxidant And Potentially Destructive If It
Accumulates Or Escapes From Peroxisomes. Ribosomes Are RNA-Protein Complexes
(Nucleoproteins) That Are Synthesized In The Nucleolus And Secreted Into The
Cytoplasm Through Pores In The Nuclear Envelope Called Nuclear Pore Complexes.
Lysosomes Are Saclike Structures That Originate From The Golgi Complex And Contain
More Than 40 Digestive Enzymes Called Hydrolases, Which Catalyze Bonds In Proteins,
Lipids, Nucleic Acids, And Carbohydrates. Oxyhydrosomes Are Involved In Enzyme
Production.
PTS: 1 REF: Page 8
4. Which Cell Component Is Capable Of Cellular Autodigestion When It Is Released
During Cell Injury?
a. Ribosome C. Smooth Endoplasmic Reticulum
b. Golgi Complex D. Lysosomes
ANS: D
, The Lysosomal Membrane Acts As A Protective Shield Between The Powerful Digestive
Enzymes Within The Lysosome And The Cytoplasm, Preventing Their Leakage Into The
Cytoplasmic Matrix. Disruption Of The Membrane By Various Treatments Or Cellular
Injury Leads To A Release Of The Lysosomal Enzymes, Which Can Then React With
Their Specific Substrates, Causing Cellular Self-Digestion. The Other Options Do Not
Correctly Describe This Process.
PTS: 1 REF: Pages 7-8
5. What Is The Sequence Of Steps In The Development Of A Digestive Enzyme By The
Pancreas Cells From The Initial Transcription To The Release From The Cell?
a. The Enzyme Is Transcribed From DNA By RNA In The Nucleus, Proceeds
To The Ribosome For Synthesis, And Is Transported In A Secretory Vesicle
To The Cell Membrane.
b. The Enzyme Is Transcribed From RNA By DNA In The Nucleus, Proceeds To
The Lysosome For Synthesis, And Is Transported In An Encapsulated Membrane
To The Cell Membrane.
c. The Enzyme Is Transcribed By The Mitochondria In The Nucleus, Proceeds To
The Ribosome For Synthesis, And Is Transported In A Cytoskeleton To The Cell
Membrane.
d. The Enzyme Is Transcribed From DNA By RNA In The Nucleus, Proceeds To
The Golgi Complex For Synthesis, And Is Transported In A Cytosol To The Cell
Membrane.
ANS: A
The Enzyme Is Transcribed From DNA By RNA In The Nucleus, Proceeds To The
Ribosome For Synthesis, And Is Transported In A Secretory Vesicle To The Cell
Membrane. The Other Options Do Not Correctly Describe This Process.
NURSINGTB.COM
PTS: 1 REF: Page 7 | Figure 1-5
6. During Which Phase Of The Cell Cycle Is DNA Synthesized?
a. G1 C. G2
b. S D. M
ANS: B
The Four Designated Phases Of The Cell Cycle Are: (1) The G1 Phase (G = Gap), Which
Is The Period Between The M Phase (M = Mitosis) And The Start Of DNA Synthesis; (2)
The S Phase (S = Synthesis), During Which DNA Is Synthesized In The Cell Nucleus; (3)
The G2 Phase, During Which RNA And Protein Synthesis Occurs, The Period Between
The Completion Of DNA Synthesis And The Next Phase (M); And (4) The M Phase,
Which Includes Nuclear And Cytoplasmic Division.
PTS: 1 REF: Page 37
7. What Organic Compound Facilitates Transportation Across Cell Membranes By
Acting As Receptors, Transport Channels For Electrolytes, And Enzymes To Drive
Active Pumps?
a. Lipids C. Proteins
b. Proteases D. Carbohydrates
ANS: C
Pathophysiology
(Author: Mccance) 8th Edition
,Table Of Contents
Part 1: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES
Unit I: THE CELL
1. Cellular Biology
2. Altered Cellular And Tissue Biology: Environmental Agents
3. The Cellular Environment: Fluids And Electrolytes, Acids And Bases
Unit II: GENES AND GENE-ENVIRONMENT INTERACTION
4. Genes And Genetic Diseases
5. Genes, Environment-Lifestyle, And Common Diseases
6. Epigenetics And Disease
Unit III: MECHANISMS OF SELF-DEFENSE
7. Innate Immunity: Inflammation
8. Adaptive Immunity
9. Alterations In Immunity And Inflammation
10. Infection
11. Stress And Disease
Unit IV. CELLULAR PROLIFERATION: CANCER
12. Cancer Biology
13. Cancer Epidemiology
14. Cancer In Children
Part 2: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS
Unit V: THE NEUROLOGIC SYSTEM
15. Structure And Function Of The Neurologic System
16. Pain, Temperature Regulation, Sleep, And Sensory Function
17. Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function
18. Disorders Of The Central And Peripheral Nervous Systems And The Neuromuscular Junction
19. Neurobiology Of Schizophrenia, Mood Disorders, And Anxiety Disorders
20. Alterations Of Neurologic Function In Children
Unit VI: THE ENDOCRINE SYSTEM
21. Mechanisms Of Hormonal Regulation
22. Alterations Of Hormonal Regulation
23. Obesity And Disorders Of Nutrition NEW
,Unit VII: THE REPRODUCTIVE SYSTEMS
24. Structure And Function Of The Reproductive Systems
25. Alterations Of The Female Reproductive System
26. Alterations Of The Male Reproductive System
27. Sexually Transmitted Infections
Unit VIII: THE HEMATOLOGIC SYSTEM
28. Structure And Function Of The Hematologic System
29. Alterations Of Erythrocyte, Platelet, And Hemostatic Function
30. Alterations Of Leukocyte And Lymphoid Function
31. Alterations Of Hematologic Function In Children
Unit IX: THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS
32. Structure And Function Of The Cardiovascular And Lymphatic Systems
33. Alterations Of Cardiovascular Function
34. Alterations Of Cardiovascular Function In Children
Unit X: THE PULMONARY SYSTEM
35. Structure And Function Of The Pulmonary System
36. Alterations Of Pulmonary Function
37. Alterations Of Pulmonary Function In Children
Unit XI: THE RENAL AND UROLOGIC SYSTEMS
38. Structure And Function Of The Renal And Urologic Systems
39. Alterations Of Renal And Urinary Function
40. Alterations Of Renal And Urinary Tract Function In Children
Unit XII: THE DIGESTIVE SYSTEM
41. Structure And Function Of The Digestive System
42. Alterations Of Digestive Function
43. Alterations Of Digestive Function In Children
Unit XIII: THE MUSCULOSKELETAL SYSTEM
44. Structure And Function Of The Musculoskeletal System
45. Alterations Of Musculoskeletal Function
46. Alterations Of Musculoskeletal Function In Children
Unit XIV: THE INTEGUMENTARY SYSTEM
47. Structure, Function, And Disorders Of The Integument
,48. Alterations Of The Integument In Children
Unit XV: MULTIPLE INTERACTING SYSTEMS
49. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Adults
50. Shock, Multiple Organ Dysfunction Syndrome, And Burns In Children
,Chapter 1: Cellular Biology
MULTIPLE CHOICE
1. Which Statement Best Describes The Cellular Function Of Metabolic Absorption?
a. Cells Can Produce Proteins. C. Cells Can Take In And Use Nutrients.
b. Cells Can Secrete Digestive Enzymes. D. Cells Can Synthesize Fats.
ANS: C
In Metabolic Absorption, All Cells Take In And Use Nutrients And Other Substances From
Their Surroundings. The Remaining Options Are Not Inclusive In Their Descriptions Of
Cellular Metabolic Absorption.
PTS: 1 REF: Page 2
2. Most Of A Cell’s Genetic Information, Including RNA And DNA, Is Contained In The:
a. Mitochondria C. Nucleolus
b. Ribosome D. Lysosome
ANS: C
The Nucleus Contains The Nucleolus, A Small Dense Structure Composed Largely Of
RNA, Most Of The Cellular DNA, And The DNA-Binding Proteins, Such As The
Histones, Which Regulate Its Activity. The Other Options Do Not Contain Most Of A
Cell’s Genetic Information.
PTS: 1 REF: Page 2
3. Which Component Of The Cell Prodnuuc erssihnygd rt obg. Ceno m
peroxide (H2O2) By Using Oxygen
To Remove Hydrogen Atoms From Specific Substrates In An Oxidative Reaction?
a. Lysosomes C. Ribosomes
b. Peroxisomes D. Oxyhydrosomes
ANS: B
Peroxisomes Are So Named Because They Usually Contain Enzymes That Use Oxygen
To Remove Hydrogen Atoms From Specific Substrates In An Oxidative Reaction That
Produces H2O2, Which Is A Powerful Oxidant And Potentially Destructive If It
Accumulates Or Escapes From Peroxisomes. Ribosomes Are RNA-Protein Complexes
(Nucleoproteins) That Are Synthesized In The Nucleolus And Secreted Into The
Cytoplasm Through Pores In The Nuclear Envelope Called Nuclear Pore Complexes.
Lysosomes Are Saclike Structures That Originate From The Golgi Complex And Contain
More Than 40 Digestive Enzymes Called Hydrolases, Which Catalyze Bonds In Proteins,
Lipids, Nucleic Acids, And Carbohydrates. Oxyhydrosomes Are Involved In Enzyme
Production.
PTS: 1 REF: Page 8
4. Which Cell Component Is Capable Of Cellular Autodigestion When It Is Released
During Cell Injury?
a. Ribosome C. Smooth Endoplasmic Reticulum
b. Golgi Complex D. Lysosomes
ANS: D
, The Lysosomal Membrane Acts As A Protective Shield Between The Powerful Digestive
Enzymes Within The Lysosome And The Cytoplasm, Preventing Their Leakage Into The
Cytoplasmic Matrix. Disruption Of The Membrane By Various Treatments Or Cellular
Injury Leads To A Release Of The Lysosomal Enzymes, Which Can Then React With
Their Specific Substrates, Causing Cellular Self-Digestion. The Other Options Do Not
Correctly Describe This Process.
PTS: 1 REF: Pages 7-8
5. What Is The Sequence Of Steps In The Development Of A Digestive Enzyme By The
Pancreas Cells From The Initial Transcription To The Release From The Cell?
a. The Enzyme Is Transcribed From DNA By RNA In The Nucleus, Proceeds
To The Ribosome For Synthesis, And Is Transported In A Secretory Vesicle
To The Cell Membrane.
b. The Enzyme Is Transcribed From RNA By DNA In The Nucleus, Proceeds To
The Lysosome For Synthesis, And Is Transported In An Encapsulated Membrane
To The Cell Membrane.
c. The Enzyme Is Transcribed By The Mitochondria In The Nucleus, Proceeds To
The Ribosome For Synthesis, And Is Transported In A Cytoskeleton To The Cell
Membrane.
d. The Enzyme Is Transcribed From DNA By RNA In The Nucleus, Proceeds To
The Golgi Complex For Synthesis, And Is Transported In A Cytosol To The Cell
Membrane.
ANS: A
The Enzyme Is Transcribed From DNA By RNA In The Nucleus, Proceeds To The
Ribosome For Synthesis, And Is Transported In A Secretory Vesicle To The Cell
Membrane. The Other Options Do Not Correctly Describe This Process.
NURSINGTB.COM
PTS: 1 REF: Page 7 | Figure 1-5
6. During Which Phase Of The Cell Cycle Is DNA Synthesized?
a. G1 C. G2
b. S D. M
ANS: B
The Four Designated Phases Of The Cell Cycle Are: (1) The G1 Phase (G = Gap), Which
Is The Period Between The M Phase (M = Mitosis) And The Start Of DNA Synthesis; (2)
The S Phase (S = Synthesis), During Which DNA Is Synthesized In The Cell Nucleus; (3)
The G2 Phase, During Which RNA And Protein Synthesis Occurs, The Period Between
The Completion Of DNA Synthesis And The Next Phase (M); And (4) The M Phase,
Which Includes Nuclear And Cytoplasmic Division.
PTS: 1 REF: Page 37
7. What Organic Compound Facilitates Transportation Across Cell Membranes By
Acting As Receptors, Transport Channels For Electrolytes, And Enzymes To Drive
Active Pumps?
a. Lipids C. Proteins
b. Proteases D. Carbohydrates
ANS: C
