Exam (elaborations) NU 150

NU 150 Exam 4

, Dopamine (anti-parkinson drug) - CORRECT ANSWERS-symptoms of Parkinson's are
caused by depletion of this

Does PO Dopamine cross the blood brain barrier? - CORRECT ANSWERS-No-
therefore it's ineffective

Levodopa (anti-parkinson drug) - CORRECT ANSWERS-crosses the blood brain barrier
and converts to Dopamine

What converts to Dopamine once it crosses the blood brain barrier? - CORRECT
ANSWERS-Levodopa

What 2 drugs work best together to reach the brain in Parkinson's? - CORRECT
ANSWERS-Levodopa and Carbidopa (anti-parkinson drugs)

Can Carbidopa be given alone and be effective? - CORRECT ANSWERS-No

Carbidopa and Levopdopa make what drug? - CORRECT ANSWERS-Sinemet

What is the "gold standard" treatment for Parkinson's? - CORRECT ANSWERS-
Levodopa

Adverse reactions of Levodopa (anti-parkinson drug) - CORRECT ANSWERS-
Choreiform movements & Dystonic Movements

What are Choreiform movements? - CORRECT ANSWERS-involuntary twitching of the
limbs or facial muscles

What are Dystonic Movements? - CORRECT ANSWERS-spasms that affect the
tongue, jaw, eyes & neck

Contraindications for Dopamine use: - CORRECT ANSWERS-1. Known hypersensitivity
2. glaucoma 3. taking MAOI 4. during lactation

What type of patients should you use precaution in before prescribing Dopamine? -
CORRECT ANSWERS-heart disease, asthma, emphysema, peptic ulcer dx, kidney &
liver disease

What are anticholinergics (anti-parkinson drug) ? - CORRECT ANSWERS-drugs that
inhibit acetylcholine in the CNS; less effective than Dopaminergic drugs.

What are Anticholinergics used for? - CORRECT ANSWERS-used to control drug-
induced extrapyramidal disorders