BB 451 (questions well answered to
pass) graded A+
nucleoside - correct answer ✔✔sugar and nitrogenous base
purines - correct answer ✔✔adenosine, guanine
pyrimidines - correct answer ✔✔cytosine, thymine, uracil
Naming purine nucleosides - correct answer ✔✔add "os" before "ine" Guanine --
>Guanosine. Adenosine.
Naming pyrimidine nucleosides - correct answer ✔✔"idine" at end instead.
Cytosine -->Cytidine. Uridine, Thymidine.
2 mechanisms that nucleotides/sides made in cells - correct answer ✔✔salvage
pathways and de novo pathways
# of rings in pyrimidines - correct answer ✔✔1 ring
# of rings in purines - correct answer ✔✔2 rings
, Salvage pathways - correct answer ✔✔use breakdown products of other
nucleotides/sides
de novo pathways - correct answer ✔✔synthesize tides/sides from scratch. AA,
carbamoyl phosphate, sugars. Activated carbon moieties from folate derivatives
Salvage pathway processes - correct answer ✔✔--nucleic acids can be broken
down to nucleoside monophosphates or individual bases. Monophosphates get re
phosphorylated to mate triphosphates to reincorporate into nucleic acids.
--also, nucleoside monophosphates can lose phosphate (nucleoside) or lose sugar
+ phosphate =base. Base be broken down or converted back to nucleoside
monophosphate.
de novo of pyrimidines - correct answer ✔✔base made apart from sugar and later
attached. Atoms in ring from aspartate and carbamoyl phosphate
de novo of purines - correct answer ✔✔base assembled on sugar. Sources of ring
include aspartate, glycine, glutamine, CO2, tetrahydrofolate derivatives
de novo of nucleotides - correct answer ✔✔Ribo is synthesized first, deoxy from
ribonucleoside diphosphates.
carbamoyl phosphate synthetase - correct answer ✔✔tunnel substrates through
enzyme to protect from H2O. NH3-->carbamic acid --> carbamoyl phosphate
pass) graded A+
nucleoside - correct answer ✔✔sugar and nitrogenous base
purines - correct answer ✔✔adenosine, guanine
pyrimidines - correct answer ✔✔cytosine, thymine, uracil
Naming purine nucleosides - correct answer ✔✔add "os" before "ine" Guanine --
>Guanosine. Adenosine.
Naming pyrimidine nucleosides - correct answer ✔✔"idine" at end instead.
Cytosine -->Cytidine. Uridine, Thymidine.
2 mechanisms that nucleotides/sides made in cells - correct answer ✔✔salvage
pathways and de novo pathways
# of rings in pyrimidines - correct answer ✔✔1 ring
# of rings in purines - correct answer ✔✔2 rings
, Salvage pathways - correct answer ✔✔use breakdown products of other
nucleotides/sides
de novo pathways - correct answer ✔✔synthesize tides/sides from scratch. AA,
carbamoyl phosphate, sugars. Activated carbon moieties from folate derivatives
Salvage pathway processes - correct answer ✔✔--nucleic acids can be broken
down to nucleoside monophosphates or individual bases. Monophosphates get re
phosphorylated to mate triphosphates to reincorporate into nucleic acids.
--also, nucleoside monophosphates can lose phosphate (nucleoside) or lose sugar
+ phosphate =base. Base be broken down or converted back to nucleoside
monophosphate.
de novo of pyrimidines - correct answer ✔✔base made apart from sugar and later
attached. Atoms in ring from aspartate and carbamoyl phosphate
de novo of purines - correct answer ✔✔base assembled on sugar. Sources of ring
include aspartate, glycine, glutamine, CO2, tetrahydrofolate derivatives
de novo of nucleotides - correct answer ✔✔Ribo is synthesized first, deoxy from
ribonucleoside diphosphates.
carbamoyl phosphate synthetase - correct answer ✔✔tunnel substrates through
enzyme to protect from H2O. NH3-->carbamic acid --> carbamoyl phosphate
