BB 451 Fatty Acid Metabolism questions
n answers rated A+
What is the chemical handle that is attached to a fatty acid? - correct answer
✔✔coenzyme a
How much energy is required to attach that handle? - correct answer ✔✔2 atp
What is the use of the handle? - correct answer ✔✔it prevents the fats from
acting as detergents
How is a fatty acid transported into the mitochondrion? - correct answer ✔✔1)
carnitine acyltransferase 1 catalyzes the swap of coenzyme A for carnitine.
2) transport protein (translocase) transports acyl-carnitine in as it transports
carnitine out (antiport)
3) becomes acyl-coa in the mitochondrial matrix
Where on the molecule does fatty acid oxidation occur? - correct answer
✔✔mitochondrial matrix
What bond is made? - correct answer ✔✔trans double bond
, What is "beta oxidation"? Where in the cell does it occur? - correct answer ✔✔it
is fatty acid oxidation it is between carbons 2 and 3 and it occurs in the
mitochondrial matrix
What happens in the first rxn of beta oxidation? - correct answer ✔✔removal of
protons and electrons to create a trans double bonded intermediate
What happens in the second rxn of beta oxidation? - correct answer ✔✔hydration
reaction where the addition of water creates and intermediate with a hydroxyl at
position 3 in the L configuration
What happens in the third rxn of beta oxidation? - correct answer ✔✔oxidizing
the hydroxyl from rxn 2 to a ketone
What happens in the fourth rxn of beta oxidation? - correct answer ✔✔split off an
acetyl-coa which is catalyzed by thiolase
What becomes of the acetyl-CoA product? - correct answer ✔✔positioned for the
CAC to oxidize it into a CO2
What are the other products of beta oxidation? - correct answer ✔✔1 of all of
these:
FADH2, NADH, acetyl-coa and a fatty acid that has been shortened by two carbons
What is difficult about oxidation of unsaturated fatty acids? - correct answer
✔✔the double bonds
n answers rated A+
What is the chemical handle that is attached to a fatty acid? - correct answer
✔✔coenzyme a
How much energy is required to attach that handle? - correct answer ✔✔2 atp
What is the use of the handle? - correct answer ✔✔it prevents the fats from
acting as detergents
How is a fatty acid transported into the mitochondrion? - correct answer ✔✔1)
carnitine acyltransferase 1 catalyzes the swap of coenzyme A for carnitine.
2) transport protein (translocase) transports acyl-carnitine in as it transports
carnitine out (antiport)
3) becomes acyl-coa in the mitochondrial matrix
Where on the molecule does fatty acid oxidation occur? - correct answer
✔✔mitochondrial matrix
What bond is made? - correct answer ✔✔trans double bond
, What is "beta oxidation"? Where in the cell does it occur? - correct answer ✔✔it
is fatty acid oxidation it is between carbons 2 and 3 and it occurs in the
mitochondrial matrix
What happens in the first rxn of beta oxidation? - correct answer ✔✔removal of
protons and electrons to create a trans double bonded intermediate
What happens in the second rxn of beta oxidation? - correct answer ✔✔hydration
reaction where the addition of water creates and intermediate with a hydroxyl at
position 3 in the L configuration
What happens in the third rxn of beta oxidation? - correct answer ✔✔oxidizing
the hydroxyl from rxn 2 to a ketone
What happens in the fourth rxn of beta oxidation? - correct answer ✔✔split off an
acetyl-coa which is catalyzed by thiolase
What becomes of the acetyl-CoA product? - correct answer ✔✔positioned for the
CAC to oxidize it into a CO2
What are the other products of beta oxidation? - correct answer ✔✔1 of all of
these:
FADH2, NADH, acetyl-coa and a fatty acid that has been shortened by two carbons
What is difficult about oxidation of unsaturated fatty acids? - correct answer
✔✔the double bonds