KUBY IMMUNOLOGY (2025) ACTUAL EXAM
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Terms in this set (194)
Immunity a state of protection from infectious disease
dried crusts derived from smallpox pustules were
Variolation
either inhaled or inserted into small cuts in the skin
Edward Jenner made smallpox vaccine from cowpox
Louis Pasteur grew bacterium that caused fowl cholera
the decrease in likelihood that a person will become
Herd Immunity infected with a pathogen if the majority of the
population is vaccinated and immune
certain white bloods cells that ingest
Phagocytes
microorganisms and other foreign material
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When Metchinikoff noticed that these cells were
more active in animals that were immunized,
Cell Mediated Immunity
therefore thought cells rather than serum were
major effectors of immunity
the soluble active molecules in the immunoglobulin
Antibodies
fraction of serum
the immunologic events that the antibodies
Humoral Immunity
(produced by B cells) participated in
the antibody-containing serum fraction from a
Antiserum
pathogen-exposed individual
the transferring of immunoglobulins to treat a
Passive Immunity disease that the individual did not make on his or
her own. short lived and limited.
the administration of a vaccine to induce one's own
immunity.
Active Immunity
long lived protection comes from memory cells that
provides protection for years.
a type of white blood cell that is responsible for
Lymphocyte
both cellular and humoral immunity.
any substance that elicits a specific response by B
Antigen
or T lymphocytes.
an individual B or T lymphocyte expresses many
Clonal Selection Theory copies of membrane receptor that is specific for a
single, distinct antigen.
detect changes that occur within the host cell by
binding to the viral proteins present in the cytosol
Cytotoxic T Lymphocytes
and initiate an early warning system to alert the cell
about the invader.
Guide the behavior of other immune cells and are
T Helper Cells pivotal for selecting the pathway taken by the
immune response
Pathogen-associated Common foreign structures that characterize whole
molecular patterns groups of pathogens and what the immune system
(PAMPs) frequently recognizes first.
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Proteins encoded in the genomic DNA and are
always expressed by many different immune cells.
Pattern Recognition
First line of defense for the quick detection of many
Receptors (PRRs)
of the typical chemical identifiers carried by the
most common invaders and bind to PAMPs.
To favor randomness in the design of some
Generation of Diversity
recognition molecules.
Recognition molecules that are in B cells and are
B-Cell Receptors
antibodies in their secreted form.
Recognition molecules that are in T cells and have
T-Cell Receptors
no soluble form.
Immune system's diversity strategy to avoid
Tolerance accidentally recognizing and destroying host tissue
that relies on self/non-self discrimination.
Theory by Polly Matzinger that states the immune
system constantly evaluates each new encounter
Danger Model
more for its potential to be dangerous versus safe to
the host than for whether it is self versus non-self.
Engage specific host recognition molecules that
Alarmins deliver a signal to immune cells to get involved
during these unnatural causes of cellular death
Rapid but less pathogen-specific, using inherited
Innate Immunity
recognition molecules and phagocytic cells
Pre-existing serum proteins that bind common
pathogen-associated structures and initiate a
Complement
cascade of labeling and destruction events in the
innate immunity.
Slow but highly specialized to the pathogen, and
Adaptive Immunity rely on randomly generated recognition receptors
made by B and T cells.
Messenger proteins that bind to receptors on
responding cells, inducing intracellular signaling
Cytokines
cascades that can result in activation, proliferation,
and differentiation of target cells.
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