RBC ABNORMALITIES QUESTIONS WITH
ACTUAL ANSWERS 2025 -2026
When,assessing,RBC,morphology,it,is,important,to,observe,cells,in,the,correct,area,of,the,smear.,This,slide
,demonstrates,thin,and,thick,areas,in,contrast,to,the,correct,area,in,the,center.,ANS,-,
02.,Normocytic,ANS,-,The,normal,red,cell,may,vary,in,size,from,6,to,8,u,and,is,termed,normocytic.
03.,Macrocytic,ANS,-
,The,general,term,used,to,describe,a,variation,in,the,size,of,RBCs,outside,of,the,normal,limits,is,anisocytosi
s.,The,measured,value,correlating,with,anisocytosis,is,the,RDW.,A,cell,>9u,is,termed,a,macrocyte.,These,ce
lls,are,often,observed,in,liver,disease.
04.,Macroovalocytes,ANS,-
,Macroovalocytes,can,be,seen,in,this,slide,and,are,the,result,of,megaloblastic,cell,proliferation,as,seen,in,B
12,and,folic,acid,deficiencies.
05.,Newborn,Macrocytes,ANS,-
,Macrocytes,may,also,be,observed,in,the,blood,of,infants,and,is,called,"physiologic,macrocytosis".,This,ma
y,persist,for,~,2,months.
06.,Microcytic,ANS,-
,RBCs,<6u,are,termed,microcytes,and,are,commonly,seen,in,iron,deficiency,anemia.,Use,the,nucleus,of,a,s
mall,mature,lymphocyte,to,judge,red,cell,size.
07.,Discocyte,ANS,-,Mature,RBCs,are,non-
nucleated,biconcave,disks.,The,general,term,used,to,describe,variation,in,shape,is,"poikilocytosis".
08.,Echinocyte,BURR,CELL,CRENATED,ANS,-,10-
30,short,spicules,or,projections,evenly,spaced,and,UNIFORM.,
MAY,BE,AN,ARTIFACT
Uremia,,pyruvate,kinase,deficiency,,bleeding,ulcer,,carcinoma,of,the,stomach,
, This,cell,type,may,be,called,an,echinocyte,or,Burr,cell.,It,can,be,identified,by,the,small,uniform,projections,
around,the,cell.,This,shape,change,is,thought,to,be,the,result,of,of,an,increase,in,the,area,of,the,outer,leafl
et,of,lipid,bilayer,as,compared,to,the,inner,layer.The,presence,of,this,cell,may,indicate,renal,disease,,liver,
disease.,ulcers,,or,cancer,of,the,stomach.
09.,Burr,Cell,ECHINOCYTE,CRENATED,ANS,-
,The,projections,are,demonstrated,nicely,by,this,stereoscan,image.
10.,Crenated,Cell,ECHINOCYTE,BURR,CELL,ANS,-
,An,echinocyte,,or,crenated,cell,,may,also,form,as,an,artifact,associated,with,increased,humidity,as,the,sli
de,is,drying,or,if,the,blood,has,been,in,EDTA,8,or,more,hours,before,the,slide,is,made.,If,you,see,crenated,c
ells,in,only,one,area,of,the,slide,or,if,EVERY,cell,is,crenated,,it,is,most,likely,artifact,and,does,not,indicate,a
ny,pathologic,state.
11.,Acanthocyte/,SPUR,CELL,ANS,-,5-10,irregular,spicules,VARYING,LENGTH,SPUR,SPUR,SPUR,
IMBALANCE,BETWEEN,RBCS,AND,PLASMA,LIPIDS,
ALCOHOLIC,LIVER,DISEASE,,POST,SPLENECTOMY,,Abetaliproteinemia,
Acanthocytes,are,identified,by,irregularly,spaced,spiny,projections,that,vary,in,length,and,number.,The,pr
esence,of,these,cells,may,indicate,liver,disease,with,the,accumulation,of,increased,cholesterol/phospholi
pid,ratio,in,some,areas,of,the,membrane.,These,cells,may,also,be,found,in,an,inherited,condition,called,ab
etalipoproteinemia.
12.,Acanthocyte/SEM,ANS,-
,The,stereoscan,image,is,helpful,to,"see",the,difference,between,an,acanthocyte,and,echinocyte.
13.,Schistocyte,ANS,-
,Schistocytes,,or,schizocytes,,are,red,cells,in,the,process,of,fragmentation,from,mechanical,or,thermal,inju
ry.,In,microangiopathic,hemolytic,anemia,red,cells,are,damaged,by,fibrin,that,forms,in,the,vasculature.,Th
ese,cell,types,may,also,be,seen,in,valvular,lesions,and,in,DIC.
14.,Schistocyte/,HELMET,CELL,ANS,-,2-3,Pointed,ends,
ACTUAL ANSWERS 2025 -2026
When,assessing,RBC,morphology,it,is,important,to,observe,cells,in,the,correct,area,of,the,smear.,This,slide
,demonstrates,thin,and,thick,areas,in,contrast,to,the,correct,area,in,the,center.,ANS,-,
02.,Normocytic,ANS,-,The,normal,red,cell,may,vary,in,size,from,6,to,8,u,and,is,termed,normocytic.
03.,Macrocytic,ANS,-
,The,general,term,used,to,describe,a,variation,in,the,size,of,RBCs,outside,of,the,normal,limits,is,anisocytosi
s.,The,measured,value,correlating,with,anisocytosis,is,the,RDW.,A,cell,>9u,is,termed,a,macrocyte.,These,ce
lls,are,often,observed,in,liver,disease.
04.,Macroovalocytes,ANS,-
,Macroovalocytes,can,be,seen,in,this,slide,and,are,the,result,of,megaloblastic,cell,proliferation,as,seen,in,B
12,and,folic,acid,deficiencies.
05.,Newborn,Macrocytes,ANS,-
,Macrocytes,may,also,be,observed,in,the,blood,of,infants,and,is,called,"physiologic,macrocytosis".,This,ma
y,persist,for,~,2,months.
06.,Microcytic,ANS,-
,RBCs,<6u,are,termed,microcytes,and,are,commonly,seen,in,iron,deficiency,anemia.,Use,the,nucleus,of,a,s
mall,mature,lymphocyte,to,judge,red,cell,size.
07.,Discocyte,ANS,-,Mature,RBCs,are,non-
nucleated,biconcave,disks.,The,general,term,used,to,describe,variation,in,shape,is,"poikilocytosis".
08.,Echinocyte,BURR,CELL,CRENATED,ANS,-,10-
30,short,spicules,or,projections,evenly,spaced,and,UNIFORM.,
MAY,BE,AN,ARTIFACT
Uremia,,pyruvate,kinase,deficiency,,bleeding,ulcer,,carcinoma,of,the,stomach,
, This,cell,type,may,be,called,an,echinocyte,or,Burr,cell.,It,can,be,identified,by,the,small,uniform,projections,
around,the,cell.,This,shape,change,is,thought,to,be,the,result,of,of,an,increase,in,the,area,of,the,outer,leafl
et,of,lipid,bilayer,as,compared,to,the,inner,layer.The,presence,of,this,cell,may,indicate,renal,disease,,liver,
disease.,ulcers,,or,cancer,of,the,stomach.
09.,Burr,Cell,ECHINOCYTE,CRENATED,ANS,-
,The,projections,are,demonstrated,nicely,by,this,stereoscan,image.
10.,Crenated,Cell,ECHINOCYTE,BURR,CELL,ANS,-
,An,echinocyte,,or,crenated,cell,,may,also,form,as,an,artifact,associated,with,increased,humidity,as,the,sli
de,is,drying,or,if,the,blood,has,been,in,EDTA,8,or,more,hours,before,the,slide,is,made.,If,you,see,crenated,c
ells,in,only,one,area,of,the,slide,or,if,EVERY,cell,is,crenated,,it,is,most,likely,artifact,and,does,not,indicate,a
ny,pathologic,state.
11.,Acanthocyte/,SPUR,CELL,ANS,-,5-10,irregular,spicules,VARYING,LENGTH,SPUR,SPUR,SPUR,
IMBALANCE,BETWEEN,RBCS,AND,PLASMA,LIPIDS,
ALCOHOLIC,LIVER,DISEASE,,POST,SPLENECTOMY,,Abetaliproteinemia,
Acanthocytes,are,identified,by,irregularly,spaced,spiny,projections,that,vary,in,length,and,number.,The,pr
esence,of,these,cells,may,indicate,liver,disease,with,the,accumulation,of,increased,cholesterol/phospholi
pid,ratio,in,some,areas,of,the,membrane.,These,cells,may,also,be,found,in,an,inherited,condition,called,ab
etalipoproteinemia.
12.,Acanthocyte/SEM,ANS,-
,The,stereoscan,image,is,helpful,to,"see",the,difference,between,an,acanthocyte,and,echinocyte.
13.,Schistocyte,ANS,-
,Schistocytes,,or,schizocytes,,are,red,cells,in,the,process,of,fragmentation,from,mechanical,or,thermal,inju
ry.,In,microangiopathic,hemolytic,anemia,red,cells,are,damaged,by,fibrin,that,forms,in,the,vasculature.,Th
ese,cell,types,may,also,be,seen,in,valvular,lesions,and,in,DIC.
14.,Schistocyte/,HELMET,CELL,ANS,-,2-3,Pointed,ends,
