LATEST
Test bank - clayton’s basic pharmacology for nurses 19th editionby michelle j. Willihnganz, samuel l.
Gurevitz, bruce clayton complete chapters guide
S
,LATEST
Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed
by the FDA. The brand name, or trademark, is the name
given to a drug by its manufacturer. The nonproprietary, or
generic, name is provided by the United States Adopted
Names Council.
DIF: Cognitive Level:
Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to
nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
compilation of drugnames, pronunciation guide, and possible future FDA approved
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
Database contains
evidence-based information on herbal medicines and herbal combination products; it
does notinclude information specific to nutritional supplements. Drug Interaction Facts
contains comprehensive information on drug interaction facts; it does not include
nutritional supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
,LATEST VERSION
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
ANS: A
Drug Facts and Comparisons contains drug monographs that describe all drugs
in atherapeutic class. Monographs are formatted as tables to allow comparison
of similarproducts, brand names, manufacturers, cost indices, and available
dosage forms Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which drug reference contains monographs about virtually every single-entity drug
availablein the United States and describes therapeutic uses of drugs, including
approved and unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS: B
AHFS Drug Information contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including
approved andunapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public
a standard, comprehensive, up-to-date look up and downloadable resource about
medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS: C
DailyMed makes available to healthcare providers and the public a standard,
comprehensive,up-to-date look up and downloadable resource about medicines. The
American Drug Index isnot appropriate for patient use. The American Hospital
Formulary is not appropriate for patient use. The drug reference is not appropriate for
patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
, LATEST VERSION
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds
of drugs that cannot be used safely without medical supervision and restricts their sale
to prescription by a licensed practitioner. The Controlled Substances Act addresses only
controlled substances andtheir categorization. The Kefauver Harris Drug Amendment
ensures drug efficacy and greaterdrug safety. Drug manufacturers are required to prove
to the FDA the effectiveness of their products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
lead tosevere psychological and physical dependence. Schedule I drugs have high
potential for abuseand no recognized medical use. Schedule III drugs have some
potential for abuse. Use may lead to low to moderate physical dependence or high
psychological dependence. Schedule IVdrugs have low potential for abuse. Use may lead
to limited physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an
outbreakof smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak
would become a priority concern in the world. Orphan diseases are not researched in a
priority manner. Preclinical research is not omitted. Extending any phase of the
research would meana longer time to develop a vaccine. The FDA must ensure that all
phases of the preclinical andclinical research phase have been completed in a safe
manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
Test bank - clayton’s basic pharmacology for nurses 19th editionby michelle j. Willihnganz, samuel l.
Gurevitz, bruce clayton complete chapters guide
S
,LATEST
Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed
by the FDA. The brand name, or trademark, is the name
given to a drug by its manufacturer. The nonproprietary, or
generic, name is provided by the United States Adopted
Names Council.
DIF: Cognitive Level:
Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to
nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
compilation of drugnames, pronunciation guide, and possible future FDA approved
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
Database contains
evidence-based information on herbal medicines and herbal combination products; it
does notinclude information specific to nutritional supplements. Drug Interaction Facts
contains comprehensive information on drug interaction facts; it does not include
nutritional supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
,LATEST VERSION
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
ANS: A
Drug Facts and Comparisons contains drug monographs that describe all drugs
in atherapeutic class. Monographs are formatted as tables to allow comparison
of similarproducts, brand names, manufacturers, cost indices, and available
dosage forms Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which drug reference contains monographs about virtually every single-entity drug
availablein the United States and describes therapeutic uses of drugs, including
approved and unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS: B
AHFS Drug Information contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including
approved andunapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public
a standard, comprehensive, up-to-date look up and downloadable resource about
medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS: C
DailyMed makes available to healthcare providers and the public a standard,
comprehensive,up-to-date look up and downloadable resource about medicines. The
American Drug Index isnot appropriate for patient use. The American Hospital
Formulary is not appropriate for patient use. The drug reference is not appropriate for
patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
, LATEST VERSION
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds
of drugs that cannot be used safely without medical supervision and restricts their sale
to prescription by a licensed practitioner. The Controlled Substances Act addresses only
controlled substances andtheir categorization. The Kefauver Harris Drug Amendment
ensures drug efficacy and greaterdrug safety. Drug manufacturers are required to prove
to the FDA the effectiveness of their products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
lead tosevere psychological and physical dependence. Schedule I drugs have high
potential for abuseand no recognized medical use. Schedule III drugs have some
potential for abuse. Use may lead to low to moderate physical dependence or high
psychological dependence. Schedule IVdrugs have low potential for abuse. Use may lead
to limited physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an
outbreakof smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak
would become a priority concern in the world. Orphan diseases are not researched in a
priority manner. Preclinical research is not omitted. Extending any phase of the
research would meana longer time to develop a vaccine. The FDA must ensure that all
phases of the preclinical andclinical research phase have been completed in a safe
manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
