NR 507 Midterm Exam
Hives (urticaria) are an example of a: ANS: Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? ANS: type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune system? ANS:
neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. ANS: type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: ANS: IgG or IgM
Type 1 hypersensitivity reaction is mediated by ANS: IgE
Allergic asthma is an example of ANS: type 1 hypersensitivity reaction
type 2 hypersensitivity ANS: tissue specific
Primary effector cells of type 2 ANS: macrophages
Examples of type 2 reactions ANS: drug allergies, hemolytic anemia, blood transfusion mismatch,
allergies against infectious agents
Type 2 causes ANS: The cell to be destroyed by the antibody
,Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction ANS: antigen-antibody response
Where does the antibody bind to the antigen in type 3 response? ANS: in blood or body fluids and then
circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? ANS: on cell surface
Primary effector cell in type 3 ANS: neutrophils
example of type 3 reaction ANS: serum sickness
type 4 hypersensitivity reaction ANS: cell-mediated response
primary mediators of type 4 ANS: lymphocytes and macrophages
type 4 mediated by ANS: T lymphocytes and do not use antibodies
example of type 4 ANS: localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: ANS: Complement damages RBC membrane causing
cell lysis.
, Which of the following is the underlying pathology for hay fever? ANS: mast cell degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: ANS: anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria?
ANS: Eosinophilia.
An example of a primary immunodeficiency is: ANS: Chronic Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. ANS: Malnutrition
Which of the following is an autoimmune disease? ANS: Systemic Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? ANS: It is the result of a single gene defect. (genetics)
Examples of secondary immunodeficiency ANS: HIV, cancer
Secondary immunodeficiency caused by ANS: external to immune system
examples of primary immunodeficiency ANS: Chronic granulomatous Disease of Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
Hives (urticaria) are an example of a: ANS: Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? ANS: type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune system? ANS:
neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. ANS: type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: ANS: IgG or IgM
Type 1 hypersensitivity reaction is mediated by ANS: IgE
Allergic asthma is an example of ANS: type 1 hypersensitivity reaction
type 2 hypersensitivity ANS: tissue specific
Primary effector cells of type 2 ANS: macrophages
Examples of type 2 reactions ANS: drug allergies, hemolytic anemia, blood transfusion mismatch,
allergies against infectious agents
Type 2 causes ANS: The cell to be destroyed by the antibody
,Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction ANS: antigen-antibody response
Where does the antibody bind to the antigen in type 3 response? ANS: in blood or body fluids and then
circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? ANS: on cell surface
Primary effector cell in type 3 ANS: neutrophils
example of type 3 reaction ANS: serum sickness
type 4 hypersensitivity reaction ANS: cell-mediated response
primary mediators of type 4 ANS: lymphocytes and macrophages
type 4 mediated by ANS: T lymphocytes and do not use antibodies
example of type 4 ANS: localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: ANS: Complement damages RBC membrane causing
cell lysis.
, Which of the following is the underlying pathology for hay fever? ANS: mast cell degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: ANS: anaphylaxis
Which of the following assessment findings would be expected in a patient who presents with urticaria?
ANS: Eosinophilia.
An example of a primary immunodeficiency is: ANS: Chronic Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. ANS: Malnutrition
Which of the following is an autoimmune disease? ANS: Systemic Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? ANS: It is the result of a single gene defect. (genetics)
Examples of secondary immunodeficiency ANS: HIV, cancer
Secondary immunodeficiency caused by ANS: external to immune system
examples of primary immunodeficiency ANS: Chronic granulomatous Disease of Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
