VM 575 (Digestive) EXAM 1 QUESTIONS
AND ACCURATE SOLUTIONS RATED A.
What drugs kill nematodes, trematodes, cestodes, and protozoa?
a. Tetrahydro pyrimidines (pyrantel)
b. Macrocyclic lactones (Ivermectin)
c. Benzimidazoles (Fenbendazole)
d. Piperazine (piperazine)
e. 1,2,4-Triazines derivatives (ponazuril)
Benzimidazoles (Fenbendazole)
What is the mode of action of piperazine?
a. Binds intestinal tubulin leading to failed glucose absorption
b. Inhibition of acetylcholinesterase
c. GABA agonist leading to paralysis
GABA agonist leading to paralysis
Organophosphate poisoning leads to SLUDD (salivation, lacrimation,
urination, digestion, and defecation) signs associated with what action of
the drug?
a. Overstimulation of nicotinic receptors
b. Overstimulation of muscarinic receptors
c. None of the Above
d. Both of the Above
Overstimulation of muscarinic receptors
The anti-parasitic drugs in the drug class 1,2,4-triazine derivatives are
often used in which situations?
a. Eimeria spp infection in poultry
b. Sarcocystis neurona infections in horses
c. Neospora caninum infection in many species
d. All of the above
All of the above
,Pyrantel (a tetrahydropyrimidine) is included in the monthly preventative
Heartgard Plus ® and can prevent which of the following parasites?
a. Trichuris vulpis
b. Cytoisospora canis
c. Dipylidium caninum
d. Ancylostoma caninum
Ancylostoma caninum
Praziquantel is the antiparasitic drug used to primarily treat which parasite
in horses?
a. Strongylus vulgaris
b. Anoplocephala perfoliata
c. Gasterophilus intestinalis
d. Cyathostomes
Anoplocephala perfoliata
A 4 yr. old Golden Retriever had intestinal parasites (hookworm and
whipworm) last year that you treated with pyrantel pamoate at 5mL/10lbs
body weight PO (supplied as 4.54 mg/mL). Is the pyrantel pamoate dose
given an adequate anthelminthic for an adult dog with whipworms and
hookworms?
a. The dose is correct, and we expect it to kill whipworms and
hookworms. A second treatment may be needed.
b. The dose is fine but the drug is not effective against whipworm. It likely
removed the hookworm but would not be expected to remove the
whipworm.
c. The dose is incorrect which may explain why the whipworms are still
present. Retreatment with a higher dose is needed.
d. The dose is incorrect. Also, it is likely that Rocky was reinfected.
The dose is fine but the drug is not effective against whipworm. It likely
removed the hookworm but would not be expected to remove the whipworm.
Given that your patient (a 4 yr. old golden retriever) has active bloody
diarrhea, should you make any recommendations about his management
to the owner? Choose all correct answers.
a. Increase Rocky's water to prevent dehydration.
b. The owner needs to clean up the diarrhea using methods designed to
,prevent transfer of zoonotic agents to the family and others.
c. Decrease Rocky's food to prevent vomiting.
d. Rocky should not go to the dog park until cleared of his infections.
e. Destroy Rocky's bedding and discard to prevent transmission to humans
and other animals.
The owner needs to clean up the diarrhea using methods designed to prevent
transfer of zoonotic agents to the family and others.
Rocky should not go to the dog park until cleared of his infections.
What is the treatment for Trichuris Vulpis (whipworms)?
Fenbendazole (Panacur®) 50 mg/kg SID for three days is a good choice
because it is effective against whipworms.
What is the treatment for a 4-month-old puppy with Toxocara, Giardia,
and hookworms?
You choose Fenbendazole because it has a spectrum of activity against both
Toxocara, Giardia, and hookworms.
A pasture of sheep have severe mixed Trichostrongyle infection with HOT,
Hemonchus, Ostertagia and Trichostrongylus, heavy Monezia tapeworm
infection, and GI damage is so severe that sheep are dying from anemia
and protein losing enteropathy. You are going to try empiric treatment for
this condition, what drug(s) might you select? Choose all treatments
expected to be efficacious.
a. Ivermectin/praziquantel
b. Trimethoprim Sulfa
c. Oxytetracycline
d. Albendazole
e. Thiabendazole
Albendazole
Ivermectin/praziquantel
What is FAMACHA Used For?
FAMACHA is a diagnostic test to help small ruminant producers identify
animals that require anthelmintic treatment and those which do not require
deworming.
, The tool is a card that matches lower eyelid color to anemia levels, an
indicator of clinical barber pole worm infection.
What is a clinical sign that would indicate that a horse may have
abdominal pain?
a. Bruxism
b. Polyuria
c. Abdominal distension
d. Flehmen
e. All of the above
all of the above
What diagnostic test should be performed on every horse with abdominal
pain?
a. Nasogastric intubation
b. Abdominal ultrasound
c. Abdominocentesis
d. CBC
Nasogastric intubation
What are the two most common causes of colic in the horse?
a. Large colon impaction and vagotonia
b. Gas colic and volvulus
c. Strangulating lipoma and impaction
d. Large colon impaction and displacement
Large colon impaction and vagotonia
What is the most common reason that a large colon impaction may
develop in the horse?
a. Stress
b. Change in diet
c. Lack of water intake
d. Increased turn out
e. B and C
B and C: Change in diet and Lack of water intake
AND ACCURATE SOLUTIONS RATED A.
What drugs kill nematodes, trematodes, cestodes, and protozoa?
a. Tetrahydro pyrimidines (pyrantel)
b. Macrocyclic lactones (Ivermectin)
c. Benzimidazoles (Fenbendazole)
d. Piperazine (piperazine)
e. 1,2,4-Triazines derivatives (ponazuril)
Benzimidazoles (Fenbendazole)
What is the mode of action of piperazine?
a. Binds intestinal tubulin leading to failed glucose absorption
b. Inhibition of acetylcholinesterase
c. GABA agonist leading to paralysis
GABA agonist leading to paralysis
Organophosphate poisoning leads to SLUDD (salivation, lacrimation,
urination, digestion, and defecation) signs associated with what action of
the drug?
a. Overstimulation of nicotinic receptors
b. Overstimulation of muscarinic receptors
c. None of the Above
d. Both of the Above
Overstimulation of muscarinic receptors
The anti-parasitic drugs in the drug class 1,2,4-triazine derivatives are
often used in which situations?
a. Eimeria spp infection in poultry
b. Sarcocystis neurona infections in horses
c. Neospora caninum infection in many species
d. All of the above
All of the above
,Pyrantel (a tetrahydropyrimidine) is included in the monthly preventative
Heartgard Plus ® and can prevent which of the following parasites?
a. Trichuris vulpis
b. Cytoisospora canis
c. Dipylidium caninum
d. Ancylostoma caninum
Ancylostoma caninum
Praziquantel is the antiparasitic drug used to primarily treat which parasite
in horses?
a. Strongylus vulgaris
b. Anoplocephala perfoliata
c. Gasterophilus intestinalis
d. Cyathostomes
Anoplocephala perfoliata
A 4 yr. old Golden Retriever had intestinal parasites (hookworm and
whipworm) last year that you treated with pyrantel pamoate at 5mL/10lbs
body weight PO (supplied as 4.54 mg/mL). Is the pyrantel pamoate dose
given an adequate anthelminthic for an adult dog with whipworms and
hookworms?
a. The dose is correct, and we expect it to kill whipworms and
hookworms. A second treatment may be needed.
b. The dose is fine but the drug is not effective against whipworm. It likely
removed the hookworm but would not be expected to remove the
whipworm.
c. The dose is incorrect which may explain why the whipworms are still
present. Retreatment with a higher dose is needed.
d. The dose is incorrect. Also, it is likely that Rocky was reinfected.
The dose is fine but the drug is not effective against whipworm. It likely
removed the hookworm but would not be expected to remove the whipworm.
Given that your patient (a 4 yr. old golden retriever) has active bloody
diarrhea, should you make any recommendations about his management
to the owner? Choose all correct answers.
a. Increase Rocky's water to prevent dehydration.
b. The owner needs to clean up the diarrhea using methods designed to
,prevent transfer of zoonotic agents to the family and others.
c. Decrease Rocky's food to prevent vomiting.
d. Rocky should not go to the dog park until cleared of his infections.
e. Destroy Rocky's bedding and discard to prevent transmission to humans
and other animals.
The owner needs to clean up the diarrhea using methods designed to prevent
transfer of zoonotic agents to the family and others.
Rocky should not go to the dog park until cleared of his infections.
What is the treatment for Trichuris Vulpis (whipworms)?
Fenbendazole (Panacur®) 50 mg/kg SID for three days is a good choice
because it is effective against whipworms.
What is the treatment for a 4-month-old puppy with Toxocara, Giardia,
and hookworms?
You choose Fenbendazole because it has a spectrum of activity against both
Toxocara, Giardia, and hookworms.
A pasture of sheep have severe mixed Trichostrongyle infection with HOT,
Hemonchus, Ostertagia and Trichostrongylus, heavy Monezia tapeworm
infection, and GI damage is so severe that sheep are dying from anemia
and protein losing enteropathy. You are going to try empiric treatment for
this condition, what drug(s) might you select? Choose all treatments
expected to be efficacious.
a. Ivermectin/praziquantel
b. Trimethoprim Sulfa
c. Oxytetracycline
d. Albendazole
e. Thiabendazole
Albendazole
Ivermectin/praziquantel
What is FAMACHA Used For?
FAMACHA is a diagnostic test to help small ruminant producers identify
animals that require anthelmintic treatment and those which do not require
deworming.
, The tool is a card that matches lower eyelid color to anemia levels, an
indicator of clinical barber pole worm infection.
What is a clinical sign that would indicate that a horse may have
abdominal pain?
a. Bruxism
b. Polyuria
c. Abdominal distension
d. Flehmen
e. All of the above
all of the above
What diagnostic test should be performed on every horse with abdominal
pain?
a. Nasogastric intubation
b. Abdominal ultrasound
c. Abdominocentesis
d. CBC
Nasogastric intubation
What are the two most common causes of colic in the horse?
a. Large colon impaction and vagotonia
b. Gas colic and volvulus
c. Strangulating lipoma and impaction
d. Large colon impaction and displacement
Large colon impaction and vagotonia
What is the most common reason that a large colon impaction may
develop in the horse?
a. Stress
b. Change in diet
c. Lack of water intake
d. Increased turn out
e. B and C
B and C: Change in diet and Lack of water intake
