A. Alzheimer's disease is a progressive, degenerative brain disorder that affects memory,
thinking, and behavior. It is the most common cause of dementia in older adults and is
characterized by the loss of neurons and synapses in the brain.
Symptoms of Alzheimer's disease usually develop slowly and worsen over time. Early symptoms
may include mild memory loss and difficulty completing familiar tasks. As the disease
progresses, individuals may experience more severe memory loss, confusion, difficulty
communicating, and difficulty with daily activities.
The cause of Alzheimer's disease is not fully understood, but genetics, environmental factors,
and lifestyle factors such as smoking and poor diet may play a role. There is no cure for
Alzheimer's disease, but there are medications and other treatments that can help manage the
symptoms and improve quality of life.
B. Alzheimer's disease is a major public health concern, affecting millions of people worldwide.
According to the World Health Organization (WHO), an estimated 50 million people worldwide
have dementia, with Alzheimer's disease being the most common cause.
The prevalence of Alzheimer's disease increases with age. It is most common in people over the
age of 65, and the risk of developing the disease doubles every five years after the age of 65.
However, Alzheimer's disease is not a normal part of aging and can also occur in younger
people.
The impact of Alzheimer's disease on individuals, families, and society is significant. The disease
can have a profound effect on a person's ability to live independently and carry out daily
activities, and it can also have a significant emotional and financial impact on caregivers and
families. The disease can also place a burden on healthcare systems and the economy, as the
cost of caring for individuals with Alzheimer's disease is often high.
2. Symptoms and progression of Alzeheimer’s disease
A. Memory loss and difficulty with cognitive tasks are common early signs of Alzheimer's
disease. Other early signs may include:
1. Struggling to complete familiar tasks: For example, having difficulty following a recipe or
remembering the rules of a favorite game.
2. Losing track of time: For example, not knowing what day of the week it is or getting lost on a
familiar route.
3. Difficulty with language: For example, having trouble finding the right words to express
oneself or understanding what others are saying.
4. Disorientation: For example, becoming lost in familiar places or not knowing how to get
home.
, 5. Mood and behavior changes: For example, becoming more anxious, depressed, or suspicious
of others.
6. Poor judgment: For example, making poor financial decisions or wearing inappropriate
clothing for the weather.
It's important to note that these symptoms can also be caused by other factors, such as stress,
depression, or a side effect of medication. If you are experiencing any of these symptoms or are
concerned about your memory or cognitive function, it's important to speak with a healthcare
professional for a proper evaluation.
B. Alzheimer's disease typically progresses through three stages: early, middle, and late. The
symptoms and their severity can vary from person to person, but the following is a general
overview of the stages of the disease and the corresponding symptoms:
1. Early stage: In the early stage of Alzheimer's disease, individuals may experience mild
memory loss and difficulty completing familiar tasks. They may also have difficulty finding the
right words to express themselves or may repeat themselves. They may also experience mood
and behavior changes and have difficulty with problem-solving and decision-making.
2. Middle stage: In the middle stage of the disease, memory loss and cognitive difficulties
become more pronounced. Individuals may have difficulty with daily activities such as bathing,
dressing, and using the bathroom. They may also experience changes in sleep patterns and
behavior, such as agitation or aggression.
3. Late stage: In the late stage of Alzheimer's disease, individuals may have severe memory loss
and cognitive decline and may be unable to communicate or recognize loved ones. They may
also have difficulty swallowing and may be incontinent. They may require full-time care and
assistance with all aspects of daily living.
It's important to note that the stages of Alzheimer's disease are not always clear-cut and the
progression of the disease can vary from person to person. It's also important to note that the
symptoms of Alzheimer's disease can be managed with medications and other treatments to
improve quality of life.
3. Causes of Alzheimer’s disease
A. There is a genetic component to Alzheimer's disease, and having certain genetic risk factors
can increase a person's likelihood of developing the disease.
One genetic risk factor for Alzheimer's disease is having a family history of the disease. If a
parent or sibling has Alzheimer's disease, a person's risk of developing the disease is increased.
However, it's important to note that not everyone with a family history of Alzheimer's disease
will develop the disease, and not everyone who develops the disease has a family history of it.
Another genetic risk factor is having certain genetic mutations, such as the APOE-e4 gene. The
APOE-e4 gene is more common in people with Alzheimer's disease, but having the gene does