CSFA SFA MODULE 1 EXAM 2025(Graded A!!)
100% CORRECT ANSWERS
Vincristine causes peripheral neuropathy which is manifested by decreased reflexes, foot drop, weak
fingers and decreased autonomic function - True
DNA alkylating agents damage tumour cells only when they are inactive - False
All alkylating agents are toxic to ______ cells - Hematologic
Which antibiotic anticancer agent is extensively used to treat paediatric sarcomas? - Dactinomycin
Cancer cells become resistant to anticancer agents through a variety of mechanisms including
enhanced production that repair damaged _________ - DNA
Cross-linking DNA promotes separation of DNA strands - False
Tumor cells are derived from normal cells in which proliferation is poorly controlled - True
Hematopoietic Agents are ________ produced by cultured mammalian cells - Glycoproteins
Alkylating agents are generally more effective against fast growing tumors than other classes of
tumors - False
Some tumors become resistant to several classes of antitumor agents, even though they have never
been exposed to some of these agents. This is called _________ drug resistance - Multi-drug
Many anticancer drugs cause toxicity that unrelated to cell growth rate - True
Antimetabolites are cell-cycle specific agents which prevent synthesis of nucleotides or inhibit
enzymes by mimicking nucleotides - True
Tumor cells are remarkably similar to noncancerous human cells - True
100% CORRECT ANSWERS
Vincristine causes peripheral neuropathy which is manifested by decreased reflexes, foot drop, weak
fingers and decreased autonomic function - True
DNA alkylating agents damage tumour cells only when they are inactive - False
All alkylating agents are toxic to ______ cells - Hematologic
Which antibiotic anticancer agent is extensively used to treat paediatric sarcomas? - Dactinomycin
Cancer cells become resistant to anticancer agents through a variety of mechanisms including
enhanced production that repair damaged _________ - DNA
Cross-linking DNA promotes separation of DNA strands - False
Tumor cells are derived from normal cells in which proliferation is poorly controlled - True
Hematopoietic Agents are ________ produced by cultured mammalian cells - Glycoproteins
Alkylating agents are generally more effective against fast growing tumors than other classes of
tumors - False
Some tumors become resistant to several classes of antitumor agents, even though they have never
been exposed to some of these agents. This is called _________ drug resistance - Multi-drug
Many anticancer drugs cause toxicity that unrelated to cell growth rate - True
Antimetabolites are cell-cycle specific agents which prevent synthesis of nucleotides or inhibit
enzymes by mimicking nucleotides - True
Tumor cells are remarkably similar to noncancerous human cells - True
