NGR 6538
Psychopharmacology
Comprehensive Final Test (Qns & Ans)
2025
Multiple Choice Questions
1. Which neurotransmitter is primarily targeted by selective
serotonin reuptake inhibitors (SSRIs) in the treatment of
depression?
a) Dopamine
b) Norepinephrine
c) Serotonin
©/2025
, d) Gamma-aminobutyric acid (GABA)
ANS: c) Serotonin
Rationale: SSRIs primarily increase the levels of serotonin in
the brain by inhibiting its reuptake, thereby alleviating symptoms
of depression.
2. What is the primary mechanism of action for atypical
antipsychotics?
a) Dopamine receptor blockade
b) Serotonin receptor blockade
c) Norepinephrine reuptake inhibition
d) Glutamate receptor modulation
ANS: a) Dopamine receptor blockade
Rationale: Atypical antipsychotics primarily work by blocking
dopamine D2 receptors, which helps in managing symptoms of
psychosis while having fewer motor side effects compared to
typical antipsychotics.
3. Which drug is most likely to cause agranulocytosis, a
potentially life-threatening side effect?
©/2025
, a) Risperidone
b) Clozapine
c) Olanzapine
d) Haloperidol
ANS: b) Clozapine
Rationale: Clozapine is known for its risk of causing
agranulocytosis, necessitating regular blood monitoring.
4. Which psychopharmacological treatment is commonly used
for bipolar disorder to stabilize mood?
a) Lithium
b) Sertraline
c) Lorazepam
d) Aripiprazole
ANS: a) Lithium
Rationale: Lithium is a mood stabilizer frequently used in the
treatment of bipolar disorder to control both manic and depressive
episodes.
©/2025
Psychopharmacology
Comprehensive Final Test (Qns & Ans)
2025
Multiple Choice Questions
1. Which neurotransmitter is primarily targeted by selective
serotonin reuptake inhibitors (SSRIs) in the treatment of
depression?
a) Dopamine
b) Norepinephrine
c) Serotonin
©/2025
, d) Gamma-aminobutyric acid (GABA)
ANS: c) Serotonin
Rationale: SSRIs primarily increase the levels of serotonin in
the brain by inhibiting its reuptake, thereby alleviating symptoms
of depression.
2. What is the primary mechanism of action for atypical
antipsychotics?
a) Dopamine receptor blockade
b) Serotonin receptor blockade
c) Norepinephrine reuptake inhibition
d) Glutamate receptor modulation
ANS: a) Dopamine receptor blockade
Rationale: Atypical antipsychotics primarily work by blocking
dopamine D2 receptors, which helps in managing symptoms of
psychosis while having fewer motor side effects compared to
typical antipsychotics.
3. Which drug is most likely to cause agranulocytosis, a
potentially life-threatening side effect?
©/2025
, a) Risperidone
b) Clozapine
c) Olanzapine
d) Haloperidol
ANS: b) Clozapine
Rationale: Clozapine is known for its risk of causing
agranulocytosis, necessitating regular blood monitoring.
4. Which psychopharmacological treatment is commonly used
for bipolar disorder to stabilize mood?
a) Lithium
b) Sertraline
c) Lorazepam
d) Aripiprazole
ANS: a) Lithium
Rationale: Lithium is a mood stabilizer frequently used in the
treatment of bipolar disorder to control both manic and depressive
episodes.
©/2025
