ASCP Hematology Exam Questions Answered Correctly 100% Guaranteed Success
Dohle bodies - Answers Light blue patches in cytoplasm of neutrophils. Infection, burns
Erythrocytes - Answers O2 transport. Produced in BM
Mean Corpuscular Hemoglobin (MCH) formula - Answers (HGBx10)/RBC
Mean Corpuscular Hemoglobin Concentration (MCHC) formulao - Answers (HGBx100)/HCT
Granulocytes - Answers Defense against bacterial infection. Produced in BM
Lymphocytes - Answers Cellular and humoral immunity. Produced in lymphoid tissue
Platelets - Answers Coagulation. Produced in BM
WBC RR - Answers 4.5-11.5 x10^3 / microL
RBC RR - Answers M: 4.6-6x10^6 / microL
F: 4-5.4x10^ / microL
HGB RR - Answers M: 14-18 g/dL
F: 12-15 g/dL
HCT RR - Answers M: 40-54%
F: 35-49%
MCV RR - Answers 80-100 fL
MCH RR - Answers 27-31 pg
MCHC RR - Answers 32-36%
PLT RR - Answers 150-450x10^3 microL
MCV first 5 days - Answers Macrocytes. Higher in preterm infants
Retic % - Answers newborns increased polychromasia
Seg % - Answers 50-70
Band % - Answers 0-5
Lymph newborn - Answers few benign immature B cells may be seen
common myeloid progenitor - Answers differentiate into erythrocytes, platelets (megaK), granulocytes
(basophils, eosinophil, neutrophil), and monocytes
, common lymphoid progenitor (CLP) - Answers T-lymph, NK cell, B-lymph
Multipotential progenitor cell - Answers Common myeloid progenitor or common lymphoid progenitor
Erytheopoiesis 1-2 month gestation - Answers yolk sac and aorta-gonads mesonephros region (gower I/II
and portland)
Erythropoiesis 3-6 month gestation - Answers liver (primary), spleen
Erythropoiesis 7 month of gestation-4 years - Answers Bone marrow (all marrow active)
Erythropoiesis adult - Answers bone marrow (pelvis, vertebrae, ribs, sternum, skull. Shafts of long bones
filled with fat-may reactivate to compensate for anemia- liver and spleen may reactivate if that fails to
keep up with demand)
Rubriblast/pronormoblast - Answers 14-24 um. N:C ratio 8:1. Royal blue cytoplasm. Fine chromatin. 1-2
nucleoli. Normally confined to bone marrow.
Prorubricyte/basophilic normoblast - Answers 12-17 um. N:C ratio 6:1. Chromatin is coarser with slightly
visible parachromatin. Nucleoli usually not visible. Normally confined to bone marrow.
Rubricyte/polychromatophilic normoblast - Answers 10-15 um. N:C ratio 4:1. Cytoplasm is
polychromatophilic due to hemoglobin production. Chromatin is clumped with distinct areas of
parachromatin. Last stage to divide. Normally confined to bone marrow.
Metarubricyte/orthochromic normoblast - Answers 8-12 um. N:C ratio 1:2. Nucleus is pyknotic. Last
nucleated stage. Normally confined to bone marrow.
Reticulocyte/Polychromatophilic erythrocyte - Answers 7-10 um. No nucleus. Cytoplasm is diffusely
basophilic (bluish tinge). Reticulum seen with supravital stain. 0.5%-1.5% of RBCs in adult peripheral
blood.
Mature erythrocyte - Answers 7-8 um. Biconcave disk. Reddish-pink cytoplasm with area of central
pallor 1/3 diameter of cell.
Megaloblastic anemia cause - Answers vitamin b12 or folic acid deficiency (ex pernicious anemia)
Megaloblastic characteristics - Answers Nucleus lags behind cytoplasm in maturation. cells grow larger
without dividing. Oval macrocytes
Iron deficiency characteristics - Answers cytoplasm lags behind nucleus in maturation due to inadequate
iron for hgb synthesis. Microcytic, hypochromic RBCs
Hemoglobin A - Answers 2 alpha + 2 beta, >95% adults, 20% newborn
Hemoglobin A2 - Answers 2 alpha + 2 delta, 1.5-3.7% adults, <1% newborns
Hemoglobin F - Answers 2 alpha + 2 gamma, <2% adults, 50-85% newborn
Dohle bodies - Answers Light blue patches in cytoplasm of neutrophils. Infection, burns
Erythrocytes - Answers O2 transport. Produced in BM
Mean Corpuscular Hemoglobin (MCH) formula - Answers (HGBx10)/RBC
Mean Corpuscular Hemoglobin Concentration (MCHC) formulao - Answers (HGBx100)/HCT
Granulocytes - Answers Defense against bacterial infection. Produced in BM
Lymphocytes - Answers Cellular and humoral immunity. Produced in lymphoid tissue
Platelets - Answers Coagulation. Produced in BM
WBC RR - Answers 4.5-11.5 x10^3 / microL
RBC RR - Answers M: 4.6-6x10^6 / microL
F: 4-5.4x10^ / microL
HGB RR - Answers M: 14-18 g/dL
F: 12-15 g/dL
HCT RR - Answers M: 40-54%
F: 35-49%
MCV RR - Answers 80-100 fL
MCH RR - Answers 27-31 pg
MCHC RR - Answers 32-36%
PLT RR - Answers 150-450x10^3 microL
MCV first 5 days - Answers Macrocytes. Higher in preterm infants
Retic % - Answers newborns increased polychromasia
Seg % - Answers 50-70
Band % - Answers 0-5
Lymph newborn - Answers few benign immature B cells may be seen
common myeloid progenitor - Answers differentiate into erythrocytes, platelets (megaK), granulocytes
(basophils, eosinophil, neutrophil), and monocytes
, common lymphoid progenitor (CLP) - Answers T-lymph, NK cell, B-lymph
Multipotential progenitor cell - Answers Common myeloid progenitor or common lymphoid progenitor
Erytheopoiesis 1-2 month gestation - Answers yolk sac and aorta-gonads mesonephros region (gower I/II
and portland)
Erythropoiesis 3-6 month gestation - Answers liver (primary), spleen
Erythropoiesis 7 month of gestation-4 years - Answers Bone marrow (all marrow active)
Erythropoiesis adult - Answers bone marrow (pelvis, vertebrae, ribs, sternum, skull. Shafts of long bones
filled with fat-may reactivate to compensate for anemia- liver and spleen may reactivate if that fails to
keep up with demand)
Rubriblast/pronormoblast - Answers 14-24 um. N:C ratio 8:1. Royal blue cytoplasm. Fine chromatin. 1-2
nucleoli. Normally confined to bone marrow.
Prorubricyte/basophilic normoblast - Answers 12-17 um. N:C ratio 6:1. Chromatin is coarser with slightly
visible parachromatin. Nucleoli usually not visible. Normally confined to bone marrow.
Rubricyte/polychromatophilic normoblast - Answers 10-15 um. N:C ratio 4:1. Cytoplasm is
polychromatophilic due to hemoglobin production. Chromatin is clumped with distinct areas of
parachromatin. Last stage to divide. Normally confined to bone marrow.
Metarubricyte/orthochromic normoblast - Answers 8-12 um. N:C ratio 1:2. Nucleus is pyknotic. Last
nucleated stage. Normally confined to bone marrow.
Reticulocyte/Polychromatophilic erythrocyte - Answers 7-10 um. No nucleus. Cytoplasm is diffusely
basophilic (bluish tinge). Reticulum seen with supravital stain. 0.5%-1.5% of RBCs in adult peripheral
blood.
Mature erythrocyte - Answers 7-8 um. Biconcave disk. Reddish-pink cytoplasm with area of central
pallor 1/3 diameter of cell.
Megaloblastic anemia cause - Answers vitamin b12 or folic acid deficiency (ex pernicious anemia)
Megaloblastic characteristics - Answers Nucleus lags behind cytoplasm in maturation. cells grow larger
without dividing. Oval macrocytes
Iron deficiency characteristics - Answers cytoplasm lags behind nucleus in maturation due to inadequate
iron for hgb synthesis. Microcytic, hypochromic RBCs
Hemoglobin A - Answers 2 alpha + 2 beta, >95% adults, 20% newborn
Hemoglobin A2 - Answers 2 alpha + 2 delta, 1.5-3.7% adults, <1% newborns
Hemoglobin F - Answers 2 alpha + 2 gamma, <2% adults, 50-85% newborn
