Malaria species - Answers Vivax and falci
Malaria life cycle - Answers Sporozoite in human, release mero to infect, ring troph, amoebiid troph
Duffy antigen - Answers Glyco receptor for Plasmodium vivax; blacks often lack Duffy antigen. Chemo
target
Vivax ID pic - Answers Schuffmers dots
Falci ID factors - Answers Black water fever, no relapse, Maureen's clefts
Babesia vector - Answers deer tick, rbc infxn
Babesia ID - Answers CROSS morph in cell, Lyme co infxn
Rickettsia vector - Answers arthropods (dog tick, mouse mite, body louse, cat flea)
How rickettsia gets transmitted - Answers Arthropod bite, gets phagocytosed
How rickettsiea infects - Answers Endothelial cells, necrotizing vasculitis, microvascular permeability
Ricketsii, akari, prowazekii, typhi - Answers Rocky mtn , rickettsapox, epidemic typhus, murine typhus
Rick.rocky mtn reservoir / vector / symptom - Answers Wild rodent / brown dog tick / severe headache
and centripetal rash
Rick.Akari / rickettsialpox reservoir/ vector/ symptom - Answers House mouse / house mouse mite /
papule to eschar. Not severe
Rick.Prowazekii (epidemic) res / vec / symp - Answers Humans / body louse feces / brill zinnser recurrent
/ Sylvatic w/ flying squirrel flea feces
Rick.Typhi (endemic) res / vec/ - Answers Rat mouse cat opossum / flea feces / less severe than
epidemic
Rickettsia Dx - Answers Presum - arthropod bite or travel. Confirm is serol/pcr/IHC biopsy
Rickettsia tx / prev - Answers Doxycycline. No vax. Control vectors
Rick -> anaplasmstacea = - Answers A. Phagocytophilum and HGA
Rick-> anaplas = erlichia - Answers Erlichia Chaffeensis and HME
Anaplasma res / vec - Answers Wild rodent / black leg tick
Erlichia res / vec - Answers White tail deer , lone star tick
, Anaplasmatscea Dx and tx - Answers Blood smear of morulae. Doxy.
VHF (viral hemorrhagic fevers) - Answers Filoviridae (Ebola)
Zoonotic
Rash early
Travel hx
Tx: supportive care (Isolate!)
Ebola - Answers Public education and quarantine
HIV is what kind of disease? - Answers Zoonotic
HIV cycle - Answers High titer 3-9 wks. Then low. Then resurg of virus with aids. All pt lifelong carrier and
infector.
HIV infection risk times - Answers 1-5 month high (no Dx) 1-2 yr low, 15 month before death high.
HIV testing - Answers Ab tests false pos. Direct tests check donor blood/organ (pcr for Ag). No cure/vax.
B. burgdorferi, b hermsii, b recurrentis - Answers Lyme, soft tick RF, louse borne RF( NO zoonosis)
burgdorferi res/vec/symp/tx - Answers Wild rodents deer ice
Black leg tick
Bullseye erythema migrans
Two tier serologic MTTT Dx
Tx doxy, amox, cefur
No vax
B hermsii (Soft tick) details - Answers Zoonosis w/ squirrel rodent
Crisis fever!
Spirochetemia
B recurrent is (louse borne) - Answers Human human body lice
Spirochetemia
Crushed louse
Rash