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Vista previa 4 fuera de 184 páginas
Examen

NBME CBSE ACTUAL TEST QUESTIONS AND ANSWERS (Quiz bank with all the correct answers) (usmle step 1) Medical examination

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Vista previa 4 fuera de 184 páginas

NBME CBSE ACTUAL TEST QUESTIONS AND ANSWERS (Quiz bank with all the correct answers) (usmle step 1) Medical examination

Vista previa del contenido

NBME CBSE ACTUALTEST QUESTIONS AND
i i i i i



ANSWERS (Quiz bank with all the correct answers)
i i i i i i i i



(usmle step 1) Medical examination
i i i i




62i yeari oldi womani -i osteoporosisi -i ai bisphosphonatei isi prescribed.i Thei expectedi
beneficiali effecti ofi thei drugi isi duei toi whichi ofi thei following?i -Answer-i Decreasedi
Osteoclasti Activity

Cohoti Studyi ofi elderlyi womeni -i relativei riski ratioi fori hipi fracturesi amongi thosei
whoi exercisei regularlyi isi 1.2i (95%i confidencei intervali ofi 1.1i toi 1.8).i Whichi ofi thei
followingi isi thei conclusioni abouti thei effecti ofi exercisei oni thei riski ofi hipi fracture?i -
Answer-i Statisticallyi Significanti Overalli Increasei Risk

52i yeari oldi mani goesi toi ERi withi chesti paini radiatingi toi hisi jawi whilei shovelingi
snow.i Pulsei isi 80/mini andi bloodi pressurei isi 130/70.i Thei mosti immediatei
treatmenti mechanismi ofi action?i -Answer-i Increasedi nitrici oxidei concentration

24i yeari oldi womani -i spilledi hoti greasei oni heri lefti legi whilei workingi ati ai fast-foodi
restaurant.i Exami ofi legi showsi 7cmi pink,i soft,i granular,i edematousi wound.i Thei
formationi ofi thisi tissuei wasi mosti likelyi causedi byi increasedi activityi ofi which?i -
Answer-
a. Vasculari Endotheliali Growthi Factori
VEGFi -i stimulatesi angiogenesiss.
TYPEi IIIi Collageni =i Bloodi Vesselsi -i earlyi woundi repair

27i yeari oldi man-i MVCi -i skulli x-rayi showsi ai linear,i nondepressedi basali skulli
fracturei -i increasedi serumi osmi andi decreasedi urini osm.i Followingi desmopressini
urinei osmi increases.i Desmopressin'si effecti isi duei toi thei activationi ofi whichi ofi
thei following?i -i Answer-i a.i Adenylyli Cyclase
i Adenylatei Cyclasei -i ATPi -i CAMPi --i PROTEKINASEi Ai --i

Cai v2

Ai 10i monthi oldi boyi -i 4i dayi historyi ofi feveri andi cough.i Hei attendsi dayi carei center.i
Chesti exami showsi intercostali retractionsi alongi withi bilateral,i diffusei wheezesi andi
expiratoryi rhonchi.i Thei infectiousi agenti mosti likelyi hasi whichi ofi thei followingi
properties?i -Answer-i Mediationi ofi Celli Entryi viai ai fusioni protein

Ai 17i yeari oldi girli ini EDi -i 15i minutesi afteri beingi stungi byi ai bee.i Mildi lighti
headednessi buti noi difficultyi swallowing-i Bilaterali wheezingi -i Whichi isi mosti
appropriatei pharmacotherapyi fori thisi patient?i -Answer-i B2-i Agonist

14i yeari oldi boyi -i 2i dayi historyi ofi sorei throati andi feveri thati peaksi ini latei afternoon.i
1i weeki ofi fatigue.i Hei recentalyi hadi sexi withi onei partner.i Physicali exami showi
cervicali lymphadenopathyi andi pharyngeali erythemai withi ai creamyi exudate.i DX?i -
Answer-i Infectiousi Mononucleosis

,57i yeari oldi mani -i radiationi therapyi fori squamousi celli carcinomai ofi thei lung.i
Despitei therapy,i tumori increasesi ini sizei andi hei diesi 6i monthsi later.i Thei
progressivei tumori growthi isi duei toi ai defecti ini celli cyclei arresti ini whichi ofi thei
followingi phasesi ofi celli cycle?i -Answer-i G1

28i yeari oldi -i livedi ini sub-Saharani Africai -i untili hei camei toi thei US.i Tempi ofi
100.4i -i imagingi showsi bilaterali hydroureteri andi hydronephrosis.i Biopsyi showsi
markedi fibrosisi andi scatteredi granulomas.i DX?i -Answer-i Schistosomiasis

Ai couplei withi ai familyi historyi ofi a-thalassemia.i Womani hasi onei genei deletioni andi
mani hasi twoi genei deletion.i Ifi thei twoi genei isi transi -i whati percentagei ofi offspringi
willi havei ai twoi genei deletion?i -Answer-i 50%

previouslyi healthyi 40i yeari broughti toi emergencyi departmenti byi heri husbandi -i 2i
dayi historyi ofi fever,i lethargy,i confusion.i PEi showsi scatteredi petechiaei andi
ecchymosesi overi thei loweri extremitiesi -i 3+i polychromasiai andi 3+i schistocytesi
andi Lowi plateletsi Dx?i -Answer-i Thrombotici Thrombocytopeniai Purpura

16i yeari oldi boyi -i isi admittedi toi thei ERi becausei ofi ai knifei woundi toi thei lefti sidei
ofi hisi chest.i Ani X-rayi ofi thei chesti showsi ani air-fluidi leveli ini thei lefti sidei ofi thei
chest,i partiali collapsei ofi thei lefti lung,i andi thei elevationi ofi thei stomachi bubble.i
Thei mediastinumi isi midline.i DX?i -Answer-i Hemopneumpothoraxi underi tension

49i yeari oldi womani -i coronaryi arteryi diseasei -i BPi 140/90i -i Highi Cholesterol,i Highi
LDLi (190),i Highi triglyceridesi (350)i -i TXi withi atorvastatini andi losartan.i Whati arei
thei effectsi oni HDLi andi Triglycerides?i -Answer-i HDLi increased
Triglyceridesi Decreased

73i yearei oldi -i diffusei weaknessi andi tinglingi ofi heri armsi andi legs.i Sensationi andi
vibrationi andi positioni isi decreasedi ini alli extremities.i Whati vitamini deficiency?i -
Answer-i Vitamini B12i -i (cyanocobalamin)
Teai andi Toasti -i lowi B12i ini diet

15i yeari oldi girli -i 3i monthi historyi ofi acnei -i whichi isi thei underlyingi causei ofi thei
patientsi acne?i -Answer-i Stimulationi ofi Sebaceousi Glandsi byi androgens
b. ACNEi =i Propionibacteriumi ACNE

4i yeari oldi fromi Brazili -i PEi showsi singlei 12x10cmi lesioni ini thei righti sidei ofi jawi withi
diffusei regulari edges.i Photomicrographsi ofi ani incisionali biopsyi (looksi likei Burkittsi
Lymphoma/i Starryi night)i -i whichi ofi thei processesi mosti likelyi toi occuri ini thei regioni
indicatedi byi thei arrow?i -Answer-i Apoptosis
b.i Endemici Burkitti lymphomai cani happeni ini Brazili asi welli asi Africai (jawi lesion,i
puffyi face).

,51i yeari oldi -i lumpi oni tonguei -i 1i packi smokingi historyi fori 30i years.i 1.5i cmi massi
oni apexi ofi tongue.i Iti isi mosti appropriatei toi evaluatei whichi lymphi nodesi firsti fori
evidencei ofi metastasis?i -Answer-i Submental

15i yeari oldi boyi -i ERi -i 2i houri historyi ofi confusioni andi agitationi -i fever,i headache,i
stiffi neck,i andi vomitingi -i sincei returnedi fromi summeri campi -i patienti isi
hallucinatingi -i lumbari puncturei -i showsi cystsi andi trophozoites-i mosti likelyi
pathogen?i -Answer-i a.
Olfactoryi Nervei
Naegleriai fowleri

17i yeari oldi -i EDi -i 30i minutesi afteri beingi foundi withi ai blanki stare.i Physicali exami
showsi rigidity.i Duringi exami hei becomesi hostilei andi assaultsi physiciani -i Pti
ingestedi whichi drug?i -Answer-i PCP

Placeboi controlledi clinicali triali -i 5000i ptsi withi essentiali hypertension.i 2500i patientsi
receivei newi drugi andi 2500i patientsi receivei placebo.i Ifi alphai isi seti ati 0.01i insteadi
ofi 0.05,i whichi ofi thei followingi isi mosti likelyi result?i -Answer-i Significanti findingsi
cani bei reportedi withi greateri confidence

17i yeari oldi -i gymnasti -i comesi toi hospitali becausei ofi lacki ofi menstruali periodi fori
6i months.i BMIi 15i Whichi isi thei causei ofi thei amenorrhea?i -Answer-i
Hypogonadotropici Hypogonadism

Ai malei stillborni isi deliveredi ati 32i weeksi -i Oligohydramniosi -i absencei ofi ai urethrali
opening.i Whichi isi mosti likelyi finding?i -Answer-i Pulmonaryi Hypoplasia

Ai 6i dayi oldi -i breasti fedi boyi ini EDi -i poori weighti gaini andi irritabilityi sincei deliveryi
-i Physicali exami showsi jaundicei andi hepatomegaly.i Thei concentrationi ofi whichi ofi
thei followingi metabolitesi isi mosti likelyi increased?i -Answer-i a.i Galactosei -i 1i -i
phosphate
b.i Congenitali intolerancei toi breasti milk

Ai 25-year-oldi mani -i comesi toi EDi -i severei musclei pain,i diffuse,i painfuli swellingi ofi
hisi neck,i underarms,i andi groini afteri campingi ini Newi Mexicoi Generalizedi scatteredi
blacki maculae.i Examinationi ofi thei righti upperi extremityi showsi erythematous,i solid,i
tenderi mass.i Massi isi drainingi bloodi andi necrotici material.i Thei mosti effectivei
antibiotici fori patienti disorderi willi interferei withi whichi ofi thei followingi processes?i -
Answer-i a.
Ribosomali Assembly
b.i Yerseniai Pestis

45i yeari oldi -i progressivei weaknessi -i musclei fasciculationsi ofi thei upperi extremitiesi
andi weaknessi ofi thei loweri extremityi -i Whati additionali findings?i -Answer-i Atrophy
b.i ALSi =i Loui Gherig

Ai newi severei respiratoryi illnessi -i Whyi usei ai killedi vaccinei vsi ai livei vaccine?i -Answer-
Avoidsi Concernsi ofi reversioni toi virulence
b.i Killedi vaccinesi -i avoidsi reversioni toi virulence

, c.i livei vaccinesi -i cani (buti rarelyi do)i causei thei diseasei they'rei designedi toi prevent

Ai 33i yeari oldi -i keratinizingi squamousi celli carcinomai ofi cervix.i Whichi ofi thei
followingi describesi pathogenesisi ofi thisi patient'si disease?i -Answer-i Inactivationi ofi
Cellulari P53
b.i p53i proteini =i tumori suppressori (iti activatesi apoptosis)i -i mosti humani cancer

Ai 54i yeari oldi -i 40i yeari historyi ofi T1DMi -i receivingi hemodialysisi fori endi stagei
renali diseasei whilei awaitingi ai kidneyi transplant.i Receivesi ai drugi thati inducesi
reticulocytei releasei fromi bonei marrowi andi stimulatesi ai cytokinei receptori thati
signalsi Jak/Stati pathway?i -Answer-i Erythropoietin
Jaki Stati -i erythropoietin

Duringi ai clinicali studyi examiningi thei effectsi ofi exercise.i Thei averagei pulsei isi
175/min.i Comparedi withi measurementi beforei thei session,i whichi isi mosti likelyi
decreased?i -i Answer-i Totali Peripherali Resistance

Ani 8-year-oldi boyi -i 3-dayi historyi ofi fever,i sorei throat,i andi itchyi eyes.i Returnedi
fromi weeki longi summeri campi thati includesi hikingi tripsi andi swimmingi -i PEi showsi
conjunctivali injectioni andi oropharyngeali edemai -i Outbreaki amongi otheri campers.
Whichi isi mosti likelyi causei ofi thisi patient'si symptoms?i -Answer-i Adenovirusi
Fever+i Sorei Throati +i Itchyi Eyes
transmittedi viai swimmingi poolsi
Conjunctivitisi Virali =i adenovirus

44- year-oldi womani -i 10i monthi historyi ofi widei redi streaksi overi heri loweri trunki
(striae)i andi weighti gaini ini facei (moonface).i Whichi additionali findings?i -Answer-i
Hypertensioni andi musclei weakness
b.i Cushingi -i hypertensioni andi musclei weakness

12i yeari oldi boyi -i paini belowi lefti kneei -unablei toi playi socceri -i Ani x-rayi showni -i
Whichi structuresi attachedi toi thei abnormali anteriori tibiali area?i -Answer-i patellari
ligament
b.i Osgood-Schlatter

Ai 65-year-oldi healthi maintenancei examsi -i Hei livesi isi ai single-familyi homei withi
hisi cati andi dog.i Hei spendi muchi ofi hisi timei ini hisi basementi woodworkingi shop.i
Thisi patienti isi increasedi riski fori lungi canceri duei toi whichi ofi thei followingi
environmentali exposures?i -i Answer-i Radon

54- year-oldi mani -i intensei overwhelmingi fear.i Whichi portioni ofi braini stimulated?i -
Answer-i Amygdala
b.i Feari =i amygdala

30i yeari oldi womani -i recurrenti URIi -i Sweati isi Salty-i Genetici testingi fori 36i mosti
commoni mutationsi showsi detectablei G551Di ini onei allelei ofi CFTRi -i Whati isi
patientsi clinicali phenotype?i -Answer-i Thei Secondi CFTRi Genei wasi noti detectedi byi
thei testingi obtained

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Subido en
9 de febrero de 2025
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184
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2024/2025
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