MLT ASCP Exam Questions with Verified Answers Latest Update 2025 Already Passed
Which one of the following statements about acetaminophen metabolism is false? - Answers It is
metabolized in the kidney
Match these autoimmune diseases with their corresponding serological markers: - Answers Primary
biliary cirrhosis Antimitochondrial antibodies
CREST syndrome Anticentromere antibodies
Wegener's granulomatosis Antineutrophilic antibodies
Rheumatic fever Antimyocardial antibodies
Which of the following factors would not affect an orally-administered drug's absorption and/or
distribution in the body? - Answers The position of the patient when the drug is taken (sitting vs.
standing)
The clinical Gram stain taken from an endocervix revealed many WBC's with both intracellular and
extracellular gram- negative diplococci. The specimen was plated onto a Modified Thayer-Martin plate
and incubated. Following incubation, colonies resembling N. gonorrheae were inoculated into separate
CTA tubes containing glucose, lactose, sucrose and maltose. The fluorescent monoclonal antibody test
was positive as well as the CTA maltose and glucose tubes. What is the most appropriate next step? -
Answers Analyze another maltose tube using a known strain of N. gonorrhoeae
Cell size is indicated by forward scatter and granularity is indicated by side scatter in flow cytometry. -
Answers TRUE
A track star was in the locker room after a competition when one of his teammates noticed light brown
circular lesions on his upper back. The agent MOST likely responsible for this condition is: - Answers
Malassezia furfur
Which of the following organisms has been known to cause epidemic tinea capitis in children but almost
never affects adults? - Answers Microsporum audouinii
It is OK to change a physician's orders without calling the office first when: - Answers It is never
acceptable to change a physician's order without calling the office or department first. All changes must
have approval beforehand.
The cell in the image is a myeloblast. The myeloblast typically has a high nuclear to cytoplasm ratio,
meaning that the nucleus size is increased compared to the amount of cytoplasm present. This cell can
be defined as a myeloblast and not another type of blast, due to the presence of the auer rod in the
cytoplasm. This is a key feature only found in myeloblasts. - Answers myeloblast picture
The purpose of C3a, C4a, C5a, the split-products of the complement cascade, is to: - Answers cause
increased vascular permeability, contraction of smooth muscle, and release of histamine from basophils.
, Calculate the red cell indices from the following set of patient data:
RBC count = 3.19 x 1012/L
Hemoglobin = 11.3 g/dL
Hematocrit = 35% - Answers MCV = 110 fL, MCH = 35 pg, MCHC = 32 g/dL
metastasis - Answers The nucleus in this cell is abnormal and appears to have divided. This finding
correlates with the presence of metastasis in the CSF.
Electrophoretic separation of hemoglobin fundamentally relies on: - Answers Net charge differences of
molecules
Which of the following red blood cells contain the most H antigen: - Answers O
What should be done if all forward and reverse ABO results are NEGATIVE? - Answers incubate at room
temperature or 4°C to enhance weak expression
Which of the following thyroid function assays is affected least by pregnancy: - Answers Free T4
The migration rate of proteins on cellulose acetate is primarily the result of: - Answers Ionic charge on
the proteins
An isolate of S. pneumoniae from a respiratory specimen gave a zone of inhibition of 18mm around a 1
ug oxacillin disk using the disk diffusion test. What should the next step be? - Answers Set up an MIC on
the isolate
The Rh nomenclature which uses the letters DCE is found in which of the following genetic models: -
Answers Fisher -Race
All of the following are considered benefits of automated isolation and extraction equipment EXCEPT: -
Answers Automated isolation equipment is cheaper and more practical
Which of the following would you expect to find in the serum of a patient who has recovered from
Hepatitis B infection within 6 months after infection? - Answers Anti-HBs
Which of the following factors do not affect hybridization? - Answers A:T content
If 100% of the cells in the gated lymphocyte population are positive for CD45 (i.e., they are leukocytes)
and 7% are B cells (represented by CD19 and CD20 positivity), approximately what percentage of T cells
would be expected? - Answers 93%
Which one of the following statements about acetaminophen metabolism is false? - Answers It is
metabolized in the kidney
Match these autoimmune diseases with their corresponding serological markers: - Answers Primary
biliary cirrhosis Antimitochondrial antibodies
CREST syndrome Anticentromere antibodies
Wegener's granulomatosis Antineutrophilic antibodies
Rheumatic fever Antimyocardial antibodies
Which of the following factors would not affect an orally-administered drug's absorption and/or
distribution in the body? - Answers The position of the patient when the drug is taken (sitting vs.
standing)
The clinical Gram stain taken from an endocervix revealed many WBC's with both intracellular and
extracellular gram- negative diplococci. The specimen was plated onto a Modified Thayer-Martin plate
and incubated. Following incubation, colonies resembling N. gonorrheae were inoculated into separate
CTA tubes containing glucose, lactose, sucrose and maltose. The fluorescent monoclonal antibody test
was positive as well as the CTA maltose and glucose tubes. What is the most appropriate next step? -
Answers Analyze another maltose tube using a known strain of N. gonorrhoeae
Cell size is indicated by forward scatter and granularity is indicated by side scatter in flow cytometry. -
Answers TRUE
A track star was in the locker room after a competition when one of his teammates noticed light brown
circular lesions on his upper back. The agent MOST likely responsible for this condition is: - Answers
Malassezia furfur
Which of the following organisms has been known to cause epidemic tinea capitis in children but almost
never affects adults? - Answers Microsporum audouinii
It is OK to change a physician's orders without calling the office first when: - Answers It is never
acceptable to change a physician's order without calling the office or department first. All changes must
have approval beforehand.
The cell in the image is a myeloblast. The myeloblast typically has a high nuclear to cytoplasm ratio,
meaning that the nucleus size is increased compared to the amount of cytoplasm present. This cell can
be defined as a myeloblast and not another type of blast, due to the presence of the auer rod in the
cytoplasm. This is a key feature only found in myeloblasts. - Answers myeloblast picture
The purpose of C3a, C4a, C5a, the split-products of the complement cascade, is to: - Answers cause
increased vascular permeability, contraction of smooth muscle, and release of histamine from basophils.
, Calculate the red cell indices from the following set of patient data:
RBC count = 3.19 x 1012/L
Hemoglobin = 11.3 g/dL
Hematocrit = 35% - Answers MCV = 110 fL, MCH = 35 pg, MCHC = 32 g/dL
metastasis - Answers The nucleus in this cell is abnormal and appears to have divided. This finding
correlates with the presence of metastasis in the CSF.
Electrophoretic separation of hemoglobin fundamentally relies on: - Answers Net charge differences of
molecules
Which of the following red blood cells contain the most H antigen: - Answers O
What should be done if all forward and reverse ABO results are NEGATIVE? - Answers incubate at room
temperature or 4°C to enhance weak expression
Which of the following thyroid function assays is affected least by pregnancy: - Answers Free T4
The migration rate of proteins on cellulose acetate is primarily the result of: - Answers Ionic charge on
the proteins
An isolate of S. pneumoniae from a respiratory specimen gave a zone of inhibition of 18mm around a 1
ug oxacillin disk using the disk diffusion test. What should the next step be? - Answers Set up an MIC on
the isolate
The Rh nomenclature which uses the letters DCE is found in which of the following genetic models: -
Answers Fisher -Race
All of the following are considered benefits of automated isolation and extraction equipment EXCEPT: -
Answers Automated isolation equipment is cheaper and more practical
Which of the following would you expect to find in the serum of a patient who has recovered from
Hepatitis B infection within 6 months after infection? - Answers Anti-HBs
Which of the following factors do not affect hybridization? - Answers A:T content
If 100% of the cells in the gated lymphocyte population are positive for CD45 (i.e., they are leukocytes)
and 7% are B cells (represented by CD19 and CD20 positivity), approximately what percentage of T cells
would be expected? - Answers 93%
