NURS 5334 Antimicrobial PAPER 2 Success
Guaranteed Answers (Verified)
Ibuprofen and naproxen are part of COX 1 or COX 2? - Inhibition Cox 1
What are three major side effects of Cox 1 inhibitors like NSAIDs and ASAs? -
Gastric ulcers
Bleeding
Renal Impairment
Inhibition of COX-2 give protection against colorectal cancer, True or False? -
True
What is the name of the one Cox-2 inhibitor that had not been taken off the
market due to its benefits for patient that are prone to GI bleed and pts with a
high risk for MI and stroke? - Celecoxib
Prescribing a patient NSAIDs in addition to corticosteroids can put a patient as
risk for what major adverse effect? - GI bleed
Regular use of this ASA can prevent colorectal cancer? What is the name of this
drug - Aspirin
Wanda is 75 years old, she had a history of Pelvic inflammatory disease,
smokes on a daily basis and was a chronic alcohol user until she quit. Should
she be prescribed any of the follow meds? (YES or NO) explain why!
Ibuprofen
Naproxen
Indomethacin - NO! Increased risk of GI bleed
, you cannot exceed ___ of acetaminophen in 24 hours. - 3grams
Why does aspirin lead to GI effects in patients? (4) - 1. Inc secretion of acid and
pepsin
2. Dec production of cytoprotective mucous and bicarbonate
3. Decreased submucosal blood flow
4. Direct irritant action of aspirin on the gastric mucosa
Clara is on lithium for her bipolar disorder. She has chronic pain. What
medication should not be prescribed to Clara due to risk for increased lithium
levels? - Celecoxib
Paula has edema on her lower extremities and is taking furosemide to release
extra urine. She stated that after starting ____ she notice that she was
releasing less and less urine. - Celecoxib
Celecoxib should be avoided in patients with this allergy? - Sulfonamide Allergy
How do Glucocorticoids work? - Interrupt the inflammatory processes. Inhibit
chemical mediators (prostaglandins, leukotrines, histamines). And suppress the
infiltration of phagocytes so damage to lysosomal enzymes are averted.
Why might a glucocorticoid be a poor choice of drug for a serious athlete? -
Drugs suppress the synthesis of of proteins from amino acids and divert amino
acids for the production of glucose, these actions can reduce muscle mass.
Why might Glucocorticoids be a poor choice for a diabetes patient? - They
elevate blood glucose
Guaranteed Answers (Verified)
Ibuprofen and naproxen are part of COX 1 or COX 2? - Inhibition Cox 1
What are three major side effects of Cox 1 inhibitors like NSAIDs and ASAs? -
Gastric ulcers
Bleeding
Renal Impairment
Inhibition of COX-2 give protection against colorectal cancer, True or False? -
True
What is the name of the one Cox-2 inhibitor that had not been taken off the
market due to its benefits for patient that are prone to GI bleed and pts with a
high risk for MI and stroke? - Celecoxib
Prescribing a patient NSAIDs in addition to corticosteroids can put a patient as
risk for what major adverse effect? - GI bleed
Regular use of this ASA can prevent colorectal cancer? What is the name of this
drug - Aspirin
Wanda is 75 years old, she had a history of Pelvic inflammatory disease,
smokes on a daily basis and was a chronic alcohol user until she quit. Should
she be prescribed any of the follow meds? (YES or NO) explain why!
Ibuprofen
Naproxen
Indomethacin - NO! Increased risk of GI bleed
, you cannot exceed ___ of acetaminophen in 24 hours. - 3grams
Why does aspirin lead to GI effects in patients? (4) - 1. Inc secretion of acid and
pepsin
2. Dec production of cytoprotective mucous and bicarbonate
3. Decreased submucosal blood flow
4. Direct irritant action of aspirin on the gastric mucosa
Clara is on lithium for her bipolar disorder. She has chronic pain. What
medication should not be prescribed to Clara due to risk for increased lithium
levels? - Celecoxib
Paula has edema on her lower extremities and is taking furosemide to release
extra urine. She stated that after starting ____ she notice that she was
releasing less and less urine. - Celecoxib
Celecoxib should be avoided in patients with this allergy? - Sulfonamide Allergy
How do Glucocorticoids work? - Interrupt the inflammatory processes. Inhibit
chemical mediators (prostaglandins, leukotrines, histamines). And suppress the
infiltration of phagocytes so damage to lysosomal enzymes are averted.
Why might a glucocorticoid be a poor choice of drug for a serious athlete? -
Drugs suppress the synthesis of of proteins from amino acids and divert amino
acids for the production of glucose, these actions can reduce muscle mass.
Why might Glucocorticoids be a poor choice for a diabetes patient? - They
elevate blood glucose
