, Lippincott®
Illustrated Reviews:
Pharmacology
Seventh Edition
, Lippincott®
Illustrated Reviews:
Pharmacology
Seventh Edition
Karen Whalen, PharmD, BCPS, FAPhA
Clinical Professor
Department of Pharmacotherapy and Translational Research
College of Pharmacy
University of Florida
Gainesville, Florida
Collaborating Editors
Carinda Feild, PharmD, FCCM
Clinical Associate Professor
Department of Pharmacotherapy and Translational Research
College of Pharmacy
University of Florida
St. Petersburg, Florida
Rajan Radhakrishnan, BPharm, MSc, PhD
Professor of Pharmacology
College of Medicine
Mohammed Bin Rashid University of Medicine and Health Sciences
Dubai, United Arab Emirates
, Acquisitions Editor : Matt Hauber
Development Editor : Andrea Vosburgh
Editorial Coordinator : Kerry McShane
Editorial Assistant : Brooks Phelps
Production Project Manager : Barton Dudlick
Design Coordinator : Stephen Druding
Art Director : Jennifer Clements
Manufacturing Coordinator : Margie Orzech
Marketing Manager : Michael McMahon
Prepress Vendor : SPi Global
Seventh Edition
Copyright © 2019 Wolters Kluwer
Copyright © 2015 Wolters Kluwer, © 2012 Wolters Kluwer Health / Lippincott Williams & Wilkins, Copyright © 2009 Lippincott
Williams & Wilkins, a Wolters Kluwer business, Copyright © 2006, 2000 Lippincott Williams & Wilkins, Copyright © 1997 Lippincott-
Raven Publishers, Copyright © 1992 J. B. Lippincott Company. All rights reserved. This book is protected by copyright. No part of this
book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies,
or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief
quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official
duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters
Kluwer Health at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at , or via our
website at lww.com (products and services).
987654321
Printed in China
Library of Congress Cataloging-in-Publication Data
Names: Whalen, Karen, editor. | Feild, Carinda, editor. | Radhakrishnan, Rajan, editor.
Title: Pharmacology / [edited by] Karen Whalen ; collaborating editors, Carinda Feild, Rajan Radhakrishnan.
Other titles: Pharmacology (Whalen) | Lippincott's illustrated reviews.Description: Seventh edition. | Philadelphia : Wolters Kluwer,
[2019] | Series: Lippincott illustrated reviews | Includes bibliographical references and index.
Identifiers: LCCN 2018030673 | ISBN 9781496384133 (pbk.)Subjects: | MESH: Pharmacology | Examination Questions | Outlines
Classification: LCC RM301.14 | NLM QV 18.2 | DDC 615/.1076—dc23 LC record available at https://lccn.loc.gov/2018030673
This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied, including any warranties as to
accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based upon healthcare professionals' examination of each patient and
consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and
other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool.
Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for
any resulting diagnosis and treatments.
Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses,
indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals
should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information
sheet (the manufacturer's package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side
effects and identify any changes in dosage schedule or contradictions, particularly if the medication to be administered is new,
infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is
assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or
otherwise, or from any reference to or use by any person of this work.
LWW.com
Illustrated Reviews:
Pharmacology
Seventh Edition
, Lippincott®
Illustrated Reviews:
Pharmacology
Seventh Edition
Karen Whalen, PharmD, BCPS, FAPhA
Clinical Professor
Department of Pharmacotherapy and Translational Research
College of Pharmacy
University of Florida
Gainesville, Florida
Collaborating Editors
Carinda Feild, PharmD, FCCM
Clinical Associate Professor
Department of Pharmacotherapy and Translational Research
College of Pharmacy
University of Florida
St. Petersburg, Florida
Rajan Radhakrishnan, BPharm, MSc, PhD
Professor of Pharmacology
College of Medicine
Mohammed Bin Rashid University of Medicine and Health Sciences
Dubai, United Arab Emirates
, Acquisitions Editor : Matt Hauber
Development Editor : Andrea Vosburgh
Editorial Coordinator : Kerry McShane
Editorial Assistant : Brooks Phelps
Production Project Manager : Barton Dudlick
Design Coordinator : Stephen Druding
Art Director : Jennifer Clements
Manufacturing Coordinator : Margie Orzech
Marketing Manager : Michael McMahon
Prepress Vendor : SPi Global
Seventh Edition
Copyright © 2019 Wolters Kluwer
Copyright © 2015 Wolters Kluwer, © 2012 Wolters Kluwer Health / Lippincott Williams & Wilkins, Copyright © 2009 Lippincott
Williams & Wilkins, a Wolters Kluwer business, Copyright © 2006, 2000 Lippincott Williams & Wilkins, Copyright © 1997 Lippincott-
Raven Publishers, Copyright © 1992 J. B. Lippincott Company. All rights reserved. This book is protected by copyright. No part of this
book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies,
or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief
quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official
duties as U.S. government employees are not covered by the above-mentioned copyright. To request permission, please contact Wolters
Kluwer Health at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103, via email at , or via our
website at lww.com (products and services).
987654321
Printed in China
Library of Congress Cataloging-in-Publication Data
Names: Whalen, Karen, editor. | Feild, Carinda, editor. | Radhakrishnan, Rajan, editor.
Title: Pharmacology / [edited by] Karen Whalen ; collaborating editors, Carinda Feild, Rajan Radhakrishnan.
Other titles: Pharmacology (Whalen) | Lippincott's illustrated reviews.Description: Seventh edition. | Philadelphia : Wolters Kluwer,
[2019] | Series: Lippincott illustrated reviews | Includes bibliographical references and index.
Identifiers: LCCN 2018030673 | ISBN 9781496384133 (pbk.)Subjects: | MESH: Pharmacology | Examination Questions | Outlines
Classification: LCC RM301.14 | NLM QV 18.2 | DDC 615/.1076—dc23 LC record available at https://lccn.loc.gov/2018030673
This work is provided “as is,” and the publisher disclaims any and all warranties, express or implied, including any warranties as to
accuracy, comprehensiveness, or currency of the content of this work.
This work is no substitute for individual patient assessment based upon healthcare professionals' examination of each patient and
consideration of, among other things, age, weight, gender, current or prior medical conditions, medication history, laboratory data and
other factors unique to the patient. The publisher does not provide medical advice or guidance and this work is merely a reference tool.
Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for
any resulting diagnosis and treatments.
Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses,
indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals
should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information
sheet (the manufacturer's package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side
effects and identify any changes in dosage schedule or contradictions, particularly if the medication to be administered is new,
infrequently used or has a narrow therapeutic range. To the maximum extent permitted under applicable law, no responsibility is
assumed by the publisher for any injury and/or damage to persons or property, as a matter of products liability, negligence law or
otherwise, or from any reference to or use by any person of this work.
LWW.com