NURS6203
Advanced Pharmacology
Comprehensive Finals Review (Qns & Ans)
2025
1. Which of the following is the primary mechanism of action of
beta-blockers?
- A) Inhibition of angiotensin-converting enzyme
- B) Blockade of beta-adrenergic receptors
- C) Stimulation of alpha-adrenergic receptors
- D) Inhibition of calcium channels
- ANS: B) Blockade of beta-adrenergic receptors
- Rationale: Beta-blockers work by blocking beta-adrenergic
receptors, reducing heart rate and blood pressure.
©2024/2025
,2. What is the primary therapeutic use of ACE inhibitors?
- A) Treatment of hyperlipidemia
- B) Management of hypertension and heart failure
- C) Treatment of diabetes mellitus
- D) Management of asthma
- ANS: B) Management of hypertension and heart failure
- Rationale: ACE inhibitors are primarily used to manage
hypertension and heart failure by inhibiting the conversion of
angiotensin I to angiotensin II.
3. Which of the following is NOT a common side effect of
opioid analgesics?
- A) Constipation
- B) Respiratory depression
- C) Nausea
- D) Hypertension
- ANS: D) Hypertension
- Rationale: Common side effects of opioid analgesics
include constipation, respiratory depression, and nausea.
Hypertension is not a common side effect.
©2024/2025
, Fill-in-the-Blank Questions
4. The __________ is the maximum concentration of a drug in
the bloodstream after administration.
- ANS: Peak plasma concentration
- Rationale: The peak plasma concentration is the maximum
concentration of a drug in the bloodstream after administration.
5. In pharmacokinetics, the __________ is the time it takes for
the plasma concentration of a drug to reduce by half.
- ANS: Half-life
- Rationale: The half-life is the time it takes for the plasma
concentration of a drug to reduce by half.
6. The __________ effect occurs when a drug is metabolized in
the liver before reaching systemic circulation.
- ANS: First-pass
- Rationale: The first-pass effect occurs when a drug is
metabolized in the liver before reaching systemic circulation,
reducing its bioavailability.
True/False Questions
7. True or False: The primary goal of pharmacodynamics is to
study the effects of drugs on the body.
©2024/2025
Advanced Pharmacology
Comprehensive Finals Review (Qns & Ans)
2025
1. Which of the following is the primary mechanism of action of
beta-blockers?
- A) Inhibition of angiotensin-converting enzyme
- B) Blockade of beta-adrenergic receptors
- C) Stimulation of alpha-adrenergic receptors
- D) Inhibition of calcium channels
- ANS: B) Blockade of beta-adrenergic receptors
- Rationale: Beta-blockers work by blocking beta-adrenergic
receptors, reducing heart rate and blood pressure.
©2024/2025
,2. What is the primary therapeutic use of ACE inhibitors?
- A) Treatment of hyperlipidemia
- B) Management of hypertension and heart failure
- C) Treatment of diabetes mellitus
- D) Management of asthma
- ANS: B) Management of hypertension and heart failure
- Rationale: ACE inhibitors are primarily used to manage
hypertension and heart failure by inhibiting the conversion of
angiotensin I to angiotensin II.
3. Which of the following is NOT a common side effect of
opioid analgesics?
- A) Constipation
- B) Respiratory depression
- C) Nausea
- D) Hypertension
- ANS: D) Hypertension
- Rationale: Common side effects of opioid analgesics
include constipation, respiratory depression, and nausea.
Hypertension is not a common side effect.
©2024/2025
, Fill-in-the-Blank Questions
4. The __________ is the maximum concentration of a drug in
the bloodstream after administration.
- ANS: Peak plasma concentration
- Rationale: The peak plasma concentration is the maximum
concentration of a drug in the bloodstream after administration.
5. In pharmacokinetics, the __________ is the time it takes for
the plasma concentration of a drug to reduce by half.
- ANS: Half-life
- Rationale: The half-life is the time it takes for the plasma
concentration of a drug to reduce by half.
6. The __________ effect occurs when a drug is metabolized in
the liver before reaching systemic circulation.
- ANS: First-pass
- Rationale: The first-pass effect occurs when a drug is
metabolized in the liver before reaching systemic circulation,
reducing its bioavailability.
True/False Questions
7. True or False: The primary goal of pharmacodynamics is to
study the effects of drugs on the body.
©2024/2025
