NBME PATHOLOGY EXAM NEWEST EXAM |
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Terms in this set (301)
A cellular adaptation Hypertrophy
characterized by
increased gene activation
leading to increased
numbers of structural
proteins and organelles.
A cellular adaptation Hyperplasia
characterized by
proliferation of stem cells
leading to an increased
total number of cells.
A cellular adaptation Atrophy
characterized by a
decrease in tissue mass
due to decrease size
and/or number of cells.
Initially due to decreased protein synthesis and loss of
Describe the cellular
fibrills/cell mass.
process of muscle
atrophy?
Later stages there is apoptosis
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, 1/27/25, 2:47 PM NBME PATHOLOGY EXAM NEWEST EXAM | QUESTIONS AND CORRECT ANSWERS | ALREADY GRADED A+ | LATEST VER…
A cellular adaptation Metaplasia
characterized by
replacement of one cell
type with another in
response to stress.
Reversible if stressor is
removed.
A cellular adaptation Dysplasia
characterized by
disordered cell growth
with high malignant
potential. Reversible if
stressor is removed.
Na/K ATPase dysfunction
What are the hallmarks of Membrane Blebbing
reversible cell injury? Chromatin Clumping
Decreased Protein synthesis (ribosome detachment)
Membrane Damage/Rupture
Rupture of Lysosomes
What are the hallmarks of Leak of cytosolic enzymes into serum
irreversible cell injury?
Mitochondrial permeability (cytochrome C release
and apoptosis)
Pyknosis-> Karyorrhexis -> Karyolysis
Nucleus turns into blobs
What is pyknosis?
"pick blobs"
What is karyorrhexis? nuclear fragmentation
What is Karyolysis? dissolution of nucleus (sign of necrosis)
What is necrosis? Disorganized cell death
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