Pharmaceutical Analysis A
American Chemical Society - Definition of Analytical Chemistry:
Analytical chemistry is the science of obtaining, processing, and communicating information about the
composition and structure of matter (anything we can see touch or is physically present). In other
words, it is the art and science of determining what matter is and how much of it exists.
CLASSIFICATION OF ANALYTICAL CHEMISTRY
1.According to method:
a. Classic wet chemistry (PA): gravimetry, titrimetry
b. Instrumental or physicochemical methods (Year 2: IA, BA)
2. According to type of information:
a. Qualitative – identity, structure
b. Quantitative – amount of analyte in a sample
3. According to type of system or matter:
Pharmaceutical Analysis (BSc: PA, IA, BA, MSc: PKA) Forensic and toxicological analysis Food
science, etc.
Pharmaceutical Analysis
Involves the analysis of medicinal drugs and compounds
1.Quality control of medicinal drugs and their dosage forms
2.Measurement of bio accessibility (release of active substance from the drug)
3.Determination of bioavailability (distribution of active substance and its metabolites in the body)
In this last case, the sample is of biological origin (patient, animal), and the analysis thereof is referred to
as bioanalysis.
1st step has to be successful if a patient wants to benefit from the drugs
American Chemical Society - Definition of Analytical Chemistry:
Analytical chemistry is the science of obtaining, processing, and communicating information about the
composition and structure of matter (anything we can see touch or is physically present). In other
words, it is the art and science of determining what matter is and how much of it exists.
CLASSIFICATION OF ANALYTICAL CHEMISTRY
1.According to method:
a. Classic wet chemistry (PA): gravimetry, titrimetry
b. Instrumental or physicochemical methods (Year 2: IA, BA)
2. According to type of information:
a. Qualitative – identity, structure
b. Quantitative – amount of analyte in a sample
3. According to type of system or matter:
Pharmaceutical Analysis (BSc: PA, IA, BA, MSc: PKA) Forensic and toxicological analysis Food
science, etc.
Pharmaceutical Analysis
Involves the analysis of medicinal drugs and compounds
1.Quality control of medicinal drugs and their dosage forms
2.Measurement of bio accessibility (release of active substance from the drug)
3.Determination of bioavailability (distribution of active substance and its metabolites in the body)
In this last case, the sample is of biological origin (patient, animal), and the analysis thereof is referred to
as bioanalysis.
1st step has to be successful if a patient wants to benefit from the drugs
