GMS 6551 UNIVERSITY OF FLORIDA EXAM WITH QUESTIONS AND MULTIPLE ANSWERS AND A CORRECT FINAL ANSWER .

which definition best describes a lead compound?

•the compound that is used for in vivo experiments
•the compound the is used for clinical trials
•the first compound discovered to have the desired activity
•the compound that is FDA approved - ANSWER the first compound discovered to
have the desired activity

which method of discovering a drug is generally the least expensive?

•natural products
•high-throughput screening
•molecular docking - ANSWER molecular docking

what is the name of the process that involves step-wise alteration of a drug to
improve its properties?

•structure activity relationship
•ADME
•target identification
•assay development - ANSWER structure activity relationship

what was the estimated research and development expenses of pharma in 2016?

•30 million
•30 bilion
•60 million
•60 billion - ANSWER 60 billion

which branch of pharmacology studies the effect of the body on drugs?

•pharmacokinetics
•pharmacodynamics
•pharmacogenetics
•pharmacotherapeutics
•toxicology - ANSWER pharmacokinetics

which branch of pharmacology studies how patients respond differently to drugs?

•pharmacokinetics
•pharmacodynamics
•pharmacogenetics
•pharmacotherapeutics
•toxicology - ANSWER pharmacogenetics

which branch of pharmacology studies the desired effect of drugs on the body,
usually at the molecular level?

•pharmacokinetics
•pharmacodynamics

, •pharmacogenetics
•pharmacotherapeutics
•toxicology - ANSWER pharmacodynamics

which branch of pharmacology studies adverse effects of drugs on the body?

•pharmacokinetics
•pharmacodynamics
•pharmacogenetics
•pharmacotherapeutics
•toxicology - ANSWER toxicology

which branch of pharmacology does excretion fall under?

•pharmacokinetics
•pharmacodynamics
•pharmacogenetics
•pharmacotherapeutics
•toxicology - ANSWER pharmacokinetics

which is the chemical name for a popular OTC painkiller?

•tylenol
•N-acetyl-para-aminophenol
•acetaminophen - ANSWER N-acetyl-para-aminophenol

which is the proprietary name for a popular OTC painkiller?

•tylenol
•N-acetyl-para-aminophenol
•acetaminophen - ANSWER tylenol

which is the non-proprietary name for a popular OTC painkiller?

•tylenol
•N-acetyl-para-aminophenol
•acetaminophen - ANSWER acetaminophen

which of the following are OTC drugs in the U.S.? select all that apply.

•codeine
•diphenhydramine
•loperamide
•levothyroxine
•6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride
•tadalafil - ANSWER •diphenhydramine
•loperamide
•6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride