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Terms in this set (114)
Explains why some perimenopausal women have
elevated estrogen level sometimes...In the early
menopause transition, elevated FSH levels are
Luteal out of phase event
adequate to recruit a second follicle which results in a
(LOOP)
follicular phase-like rise in estradiol secretion
superimposed on the mid-to-late luteal phase of the
ongoing ovulatory cycle.
Obese women are more likely to have anovulatory
cycles with high estradiol levels. They are also more
Obese women and
likely to have lower premenopause yet higher
estradiol levels during
postmenopause estradiol levels compared with
menopause
women of normal weight. (why they are at higher risk
of endometrial cancer)
Chinese and Japanese These ethnic groups have lower estradiol levels then
women white, black and hispanic women.
late menopause stage: 5-8 years after FMP. Somatic
stage +2 aging predominates. Increased genitourinary
symptoms.
early post menopause: 2 years after FMP. FSH rises,
Stages +1a, +1b, +1c
estradiol decreases. VMS predominate.
Elevated FSH, LH Endocrine labs after menopause
, These hormones work during reproductive years to
AMH, inhibin B
not deplete follicle pool too quickly.
Menstrual cycle shortenes, follicular phase
Phases during menopause
compresses, women spend more time in luteal phase..
transition and PMS
meaning more premenstrual symptoms and more
symptoms
frequent menstrual periods.
many pitfalls, variable depending on the day of the
How to respond if a
cycle you draw the lab, normal or low FSH is not
patient requests FSH lab?
helpful.
The potentially superior AMH
marker of menopause, a
lab.
Adrenal androgens: precursor hromones produced
DHEA
by the adrenal gland that are enzymatically converted
(dehydroepiandrosterone)
to active androgens or estrogens in peripheral tissues.
Location of estrogen Vagina, vulva, urethra, trigone of the bladder
receptors
maintain blood flow, the collagen, and HA within the
Effects of estrogen on
epithelial surfaces. Supports microbiome and protects
tissue
tissue from pathogens.
Vaginal changes with Thinning, loss of elasticity, loss or absence or rugae.
menopause
Vagina and urethra in vagina narrows, urethra moves closer to the introitus.
menopause
Stress urinary Vaginal estrogen and urinary incontinence: what type
incontinence does it help with?
Minoxidil, spironolactone, finasteride, estrogen
Treatment for FPHL
therapy