TEST BANK PATHOPHYSIOLOGY The Biologic Basis For Disease In Adults And Children 8 TH EDITION BY KATHRYN L. MCCANCE

TEST BANK
PATHOPHYSIOLOGY
The Biologic Basis For Disease In
Adults And Children
8TH EDITION BY KATHRYN L.
MCCANCE

,McCance: Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition) TEST
BANK


CONTENTS:
Chapter 01: Cellular Biology
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases
Chapter 04: Genes and Genetic Diseases
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases
Chapter 06: Epigenetics and Disease
Chapter 07: Innate Immunity: Inflammation and Wound Healing
Chapter 08: Adaptive Immunity
Chapter 09: Alterations in Immunity and Inflammation
Chapter 10: Infection
Chapter 11: Stress and Disease
Chapter 12: Cancer Biology
Chapter 13: Cancer Epidemiology
Chapter 14: Cancer in Children
Chapter 15: Structure and Function of the Neurologic System
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders
Chapter 20: Alterations of Neurologic Function in Children
Chapter 21: Mechanisms of Hormonal Regulation
Chapter 22: Alterations of Hormonal Regulation
Chapter 23: Obesity and Disorders of Nutrition
Chapter 24: Structure and Function of the Reproductive Systems
Chapter 25: Alterations of the Female Reproductive System
Chapter 26: Alterations of the Male Reproductive System
Chapter 27: Sexually Transmitted Infections
Chapter 28: Structure and Function of the Hematologic System
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function
Chapter 30: Alterations of Leukocyte and Lymphoid Function
Chapter 31: Alterations of Hematologic Function in Children
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems
Chapter 33: Alterations of Cardiovascular Function
Chapter 34: Alterations of Cardiovascular Function in Children
Chapter 35: Structure and Function of the Pulmonary System
Chapter 36: Alterations of Pulmonary Function
Chapter 37: Alterations of Pulmonary Function in Children
Chapter 38: Structure and Function of the Renal and Urologic Systems
Chapter 39: Alterations of Renal and Urinary Tract Function
Chapter 40: Alterations of Renal and Urinary Tract Function in Children
Chapter 41: Structure and Function of the Digestive System
Chapter 42: Alterations of Digestive Function
Chapter 43: Alterations of Digestive Function in Children
Chapter 44: Structure and Function of the Musculoskeletal System
Chapter 45: Alterations of Musculoskeletal Function
Chapter 46: Alterations of Musculoskeletal Function in Children
Chapter 47: Structure, Function, and Disorders of the Integument
Chapter 48: Alterations of the Integument in Children
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children

, McCance:okPathophysiology:okTheokBiologicokBasisokforokDiseaseokinokAdultsokandokChildrenok(8thokEdition)okTESTokB
ANK


Part 1: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES
Unit I: THE CELL

CHAPTER 01: CELLULAR BIOLOGY

MULTIPLE CHOICE

1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive enzymes.
c. Cells can take in and use nutrients.
d. Cells can synthesize fats.

ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances from their
surroundings. The remaining options are not inclusive in their descriptions of cellular metabolic
absorption.

PTS: 1 DIF: Cognitive Level: Remembering



2. Whereokisokmostokofokaokcell’sokgeneticokinformation,okincludingokRNAokandokDNA,okcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome

ANS:o k C
Theoknucleusokcontainsoktheoknucleolus,okaoksmallokdenseokstructureokcomposedoklargelyokofokRNA,okmos
tokofoktheokcellularokDNA,okandoktheokDNA-
bindingokproteins,oksuchokasoktheokhistones,okwhichokregulateokitsokactivity.okTheokmitochondriaokareokres
ponsibleokforokcellularokrespirationokandokenergyokproduction.
Ribosomes’okchiefokfunctionokisoktookprovideoksitesokforokcellularokproteinoksynthesis.okLysosomesokfuncti
onokasoktheokintracellularokdigestiveoksystem.

PTS:o k o k 1 DIF: CognitiveokLevel:okRemembering

3. Whichokcomponentokofoktheokcellokproducesokhydrogenokperoxideok(H2O2)okbyokusingokoxygenoktookre
moveokhydrogenokatomsokfromokspecificoksubstratesokinokanokoxidativeokreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome

ANS:o k B

, McCance:okPathophysiology:okTheokBiologicokBasisokforokDiseaseokinokAdultsokandokChildrenok(8thokEdition)okTESTokB
ANK


Peroxisomesokareoksooknamedokbecauseoktheyokusuallyokcontainokenzymesokthatokuseokoxygenoktookremo
veokhydrogenokatomsokfromokspecificoksubstratesokinokanokoxidativeokreactionokthatokproducesokH2O2,okwh
ichokisokaokpowerfulokoxidantokandokpotentiallyokdestructiveokifokitokaccumulatesokorokescapesokfromokpero
xisomes.
RibosomesokareokRNA-
proteinokcomplexesok(nucleoproteins)okthatokareoksynthesizedokinoktheoknucleolusokandoksecretedokintookt
heokcytoplasmokthroughokporesokinoktheoknuclearokenvelopeokcalledoknuclearokporeokcomplexes.okLysoso
mesokareoksaclikeokstructuresokthatokoriginateokfromoktheokGolgiokcomplexokandokcontainokmoreokthanok40ok
digestiveokenzymesokcalledokhydrolases,okwhichokcatalyzeokbondsokinokproteins,oklipids,oknucleicokacids
,okandokcarbohydrates.okAnokendosomeokisokaokvesicalokthatokhasokbeenokpinchedokoffokfromoktheokcellularok
membrane.

PTS:o k o k 1 DIF: CognitiveokLevel:okRemembering

4. Whichokcellokcomponentokisokcapableokofokcellularokautodigestionokwhenokitokisokreleasedokduringokcellokinjury?
a. Ribosome
b. Golgiokcomplex
c. Smoothokendoplasmicokreticulu
m
d. Lysosomes

ANS:o k D
Theoklysosomalokmembraneokactsokasokaokprotectiveokshieldokbetweenoktheokpowerfulokdigestiveokenzym
esokwithinoktheoklysosomeokandoktheokcytoplasm,okpreventingoktheirokleakageokintooktheokcytoplasmicokm
atrix.okDisruptionokofoktheokmembraneokbyokvariousoktreatmentsokorokcellularokinjuryokleadsoktookaokreleas
eokofoktheoklysosomalokenzymes,okwhichokcanokthenokreactokwithoktheirokspecificoksubstrates,okcausingokce
llularokself-
okdigestion.okTheokchiefokfunctionokofokaokribosomeokisoktookprovideoksitesokforokcellularokproteinoksynthesis

.okTheokGolgiokcomplexokisokaoknetworkokofokflattened,oksmoothokvesiclesokandokmembranesokoftenoklocate
doknearoktheokcelloknucleus.okTheoksmoothokendoplasmicokreticulumokisokinvolvedokinoksteroidokhormoneok
productionokandokremovingoktoxicoksubstancesokfromoktheokcell.

PTS:o k o k 1 DIF: CognitiveokLevel:okRemembering

5. WhichokcAMP-mediatedokresponseokisokrelatedoktookantidiureticokhormone?
a. Increasedokheartokrateokandokforceokofokcontracti
on
b. Secretionokofokcortisol
c. Increasedokretentionokofokwater
d. Breakdownokofokfat

ANS:o k C
Antidiureticokhormoneokleadsoktookincreasedokretentionokofokwaterokinoktheokbody.okEpinephrineokcauseso
kincreasesokinokheartokrateokandokforceokofokcontraction.okIncreased okcortisoloksecretionokisokdueoktookACT

H.okBreakdownokofokfatokisokdueoktookglucagon.

PTS:o k o k 1 DIF: CognitiveokLevel:okRemembering

6. DuringokwhichokphaseokofoktheokcellokcycleokisokDNAoksynthesized?
a. G1
b. S
c. G2
d. M