Test bank for Tietz Fundamentals of Clinical Chemistry
and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
Table of contents:
I. Principles Of Laboratory Medicine
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
Chapter 3. Clinical Evaluation of Methods
Chapter 4. Evidence-Based Laboratory Medicine
Chapter 5. Establishment and Use of Reference Values
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
Chapter 7. Quality Management
II. Analytical Techniques And Instrumentation
Chapter 8. Principles of Basic Techniques and Laboratory Safety
Chapter 9. Optical Techniques
Chapter 10. Electrochemistry and Chemical Sensors
Chapter 11. Electrophoresis
Chapter 12. Chromatography
Chapter 13. Mass Spectrometry
Chapter 14. Enzyme and Rate Analyses
Chapter 15. Immunochemical Techniques
Chapter 16 Automation
Chapter 17. Point-of-Care Instrumentation
III. Analytes
Chapter 18. Amino Acids, Peptides, and Proteins
Chapter 19. Serum Enzymes
Chapter 20. Tumor Markers and Cancer Genes
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
Chapter 22. Carbohydrates
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
Chapter 24. Electrolytes and Blood Gases
Chapter 25. Hormones
Chapter 26. Catecholamines and Serotonin
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
Chapter 28. Hemoglobin, Iron, and Bilirubin
Chapter 29. Porphyrins and Porphyrias
Chapter 30. Therapeutic Drugs and Their Management
Chapter 31. Clinical Toxicology
Chapter 32. Toxic Metals
IV. Pathophysiology
Chapter 33. Diabetes
,Chapter 34. Cardiovascular Disease
Chapter 35. Kidney Disease
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
Chapter 37. Liver Disease
Chapter 38. Gastrointestinal and Pancreatic Diseases
Chapter 39. Disorders of Bone and Mineral Metabolism
Chapter 40. Disorders of the Pituitary Gland
Chapter 41. Disorders of the Adrenal Cortex
Chapter 42. Thyroid Disorders
Chapter 43. Reproduction-Related Disorders
Chapter 44. Pregnancy and Prenatal Testing
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
Chapter 46. Pharmacogenetics
V. Molecular Diagnostics
Chapter 47. Principles of Molecular Biology
Chapter 48. Nucleic Acid Techniques and Applications
Chapter 49. Genomes and Nucleic Acid Alterations
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
TestBank
MULTIPLE CHOICE
1. An rindividual rworking rin ra rclinical rchemistry rlaboratory ris rmarried rto ra rsales
rrepresentative rwho rworks rfor ra rcompany rthat rsells rchemistry rlaboratory rsupplies. rWhen
rthe rlaboratory rmanager rrequests ra rlist rof rneeded rsupplies, rcost rof rsupplies, rand rvendors,
rthis rindividual ronlyrrecommends rthe rspouse’s rcompany ras rthe rvendor. rThis ris rconsidered
rto rbe ra(n):
a. accounting rissue.
b. possible rconflict rof rinterest.
c. maintenance rof rconfidentiality rissue.
d. problem rwith rresource rallocation.
ANS: r B
Concern rhas rbeen rraised rover rthe rinterrelationships rbetween rpractitioners rin rthe rmedical
rfieldrand rcommercial rsuppliers rof rdrugs, rdevices, requipment, retc., rto rthe rmedical
rprofession.
Similarly, rrelationships rhave rbeen rscrutinized rbetween rclinical rlaboratorians rand
rmanufacturers rand rproviders rof rdiagnostic requipment rand rsupplies. rThese rconcerns rled
rthe rNational rInstitutes rof rHealth r(NIH) rin r1995 rto rrequire rofficial rinstitutional rreview rof
rfinancial rdisclosure rby rresearchers rand rmanagement rof rsituations rin rwhich rdisclosure
rindicates rpotentialrconflicts rof rinterest.
DIF: 1 REF: r r rPage r4-5 OBJ: r 6 r| r7
2. A rpatient rvisits rher rphysician rstating rthat rher rprescribed rpainkiller ris rnot rworking rto
rreduce rthe rpain rfollowing rher rrecent rsurgery. rA rfriend rof rthe rpatient rclaims rthat rthe
rsame rpainkillerr“worked rwonders” rto rreduce rher rpain rafter rthe rsame rsurgery. rThe
rphysician rstates rthat rthe rdifference rin rthe reffect rof rthe rdrug rmight rbe rcaused rby ,
rwhich ris rstudied rin rpharmacogenetics.
a. epidemiology
b. an rinherited rdisease
c. a rconflict rof rinterest
d. a rgenetic rvariation rin rdrug-metabolizing renzymes
ANS: r D
Pharmacogenetics ris rthe rstudy rof rthe rgenetic rvariation rof rdrug rmetabolism
rbetweenrindividuals.
DIF: 1 REF: r r rPage r3 OBJ: r 1
3. John rworks rin ra rmolecular rdiagnostics rlaboratory rand rreceives ra rblood rsample rthat rhas
rthe rname rof ra rclose rfriend rprinted ron rthe rbar-coded rlabel. rThe rgenetic rtest rthat ris
rordered ron rtherfriend’s rsample rwould rprovide rdiagnostic rinformation rabout ra rdisorder
rthat rhas ra rpoor rprognosis, rand rthe rtest ris rusually rperformed rby rJohn. rHe rasks ra rfellow
remployee rto ranalyzerthe rsample rfor rhim rand rnot rdivulge rthe rresults. rThis rethical rissue
rconcerns:
a. confidentiality rof rpatient rgenetic rand rmedical rinformation.
b. a rconflict rof rinterest.
c. resource rallocation.
d. diagnostic raccuracy.
and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
Table of contents:
I. Principles Of Laboratory Medicine
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
Chapter 3. Clinical Evaluation of Methods
Chapter 4. Evidence-Based Laboratory Medicine
Chapter 5. Establishment and Use of Reference Values
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
Chapter 7. Quality Management
II. Analytical Techniques And Instrumentation
Chapter 8. Principles of Basic Techniques and Laboratory Safety
Chapter 9. Optical Techniques
Chapter 10. Electrochemistry and Chemical Sensors
Chapter 11. Electrophoresis
Chapter 12. Chromatography
Chapter 13. Mass Spectrometry
Chapter 14. Enzyme and Rate Analyses
Chapter 15. Immunochemical Techniques
Chapter 16 Automation
Chapter 17. Point-of-Care Instrumentation
III. Analytes
Chapter 18. Amino Acids, Peptides, and Proteins
Chapter 19. Serum Enzymes
Chapter 20. Tumor Markers and Cancer Genes
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
Chapter 22. Carbohydrates
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
Chapter 24. Electrolytes and Blood Gases
Chapter 25. Hormones
Chapter 26. Catecholamines and Serotonin
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
Chapter 28. Hemoglobin, Iron, and Bilirubin
Chapter 29. Porphyrins and Porphyrias
Chapter 30. Therapeutic Drugs and Their Management
Chapter 31. Clinical Toxicology
Chapter 32. Toxic Metals
IV. Pathophysiology
Chapter 33. Diabetes
,Chapter 34. Cardiovascular Disease
Chapter 35. Kidney Disease
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
Chapter 37. Liver Disease
Chapter 38. Gastrointestinal and Pancreatic Diseases
Chapter 39. Disorders of Bone and Mineral Metabolism
Chapter 40. Disorders of the Pituitary Gland
Chapter 41. Disorders of the Adrenal Cortex
Chapter 42. Thyroid Disorders
Chapter 43. Reproduction-Related Disorders
Chapter 44. Pregnancy and Prenatal Testing
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
Chapter 46. Pharmacogenetics
V. Molecular Diagnostics
Chapter 47. Principles of Molecular Biology
Chapter 48. Nucleic Acid Techniques and Applications
Chapter 49. Genomes and Nucleic Acid Alterations
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
TestBank
MULTIPLE CHOICE
1. An rindividual rworking rin ra rclinical rchemistry rlaboratory ris rmarried rto ra rsales
rrepresentative rwho rworks rfor ra rcompany rthat rsells rchemistry rlaboratory rsupplies. rWhen
rthe rlaboratory rmanager rrequests ra rlist rof rneeded rsupplies, rcost rof rsupplies, rand rvendors,
rthis rindividual ronlyrrecommends rthe rspouse’s rcompany ras rthe rvendor. rThis ris rconsidered
rto rbe ra(n):
a. accounting rissue.
b. possible rconflict rof rinterest.
c. maintenance rof rconfidentiality rissue.
d. problem rwith rresource rallocation.
ANS: r B
Concern rhas rbeen rraised rover rthe rinterrelationships rbetween rpractitioners rin rthe rmedical
rfieldrand rcommercial rsuppliers rof rdrugs, rdevices, requipment, retc., rto rthe rmedical
rprofession.
Similarly, rrelationships rhave rbeen rscrutinized rbetween rclinical rlaboratorians rand
rmanufacturers rand rproviders rof rdiagnostic requipment rand rsupplies. rThese rconcerns rled
rthe rNational rInstitutes rof rHealth r(NIH) rin r1995 rto rrequire rofficial rinstitutional rreview rof
rfinancial rdisclosure rby rresearchers rand rmanagement rof rsituations rin rwhich rdisclosure
rindicates rpotentialrconflicts rof rinterest.
DIF: 1 REF: r r rPage r4-5 OBJ: r 6 r| r7
2. A rpatient rvisits rher rphysician rstating rthat rher rprescribed rpainkiller ris rnot rworking rto
rreduce rthe rpain rfollowing rher rrecent rsurgery. rA rfriend rof rthe rpatient rclaims rthat rthe
rsame rpainkillerr“worked rwonders” rto rreduce rher rpain rafter rthe rsame rsurgery. rThe
rphysician rstates rthat rthe rdifference rin rthe reffect rof rthe rdrug rmight rbe rcaused rby ,
rwhich ris rstudied rin rpharmacogenetics.
a. epidemiology
b. an rinherited rdisease
c. a rconflict rof rinterest
d. a rgenetic rvariation rin rdrug-metabolizing renzymes
ANS: r D
Pharmacogenetics ris rthe rstudy rof rthe rgenetic rvariation rof rdrug rmetabolism
rbetweenrindividuals.
DIF: 1 REF: r r rPage r3 OBJ: r 1
3. John rworks rin ra rmolecular rdiagnostics rlaboratory rand rreceives ra rblood rsample rthat rhas
rthe rname rof ra rclose rfriend rprinted ron rthe rbar-coded rlabel. rThe rgenetic rtest rthat ris
rordered ron rtherfriend’s rsample rwould rprovide rdiagnostic rinformation rabout ra rdisorder
rthat rhas ra rpoor rprognosis, rand rthe rtest ris rusually rperformed rby rJohn. rHe rasks ra rfellow
remployee rto ranalyzerthe rsample rfor rhim rand rnot rdivulge rthe rresults. rThis rethical rissue
rconcerns:
a. confidentiality rof rpatient rgenetic rand rmedical rinformation.
b. a rconflict rof rinterest.
c. resource rallocation.
d. diagnostic raccuracy.
