1/4/25, 5:25 PM WGU: D027: Advanced Pathopharmacological Foundations (2025) |COMPLETE GUIDE WITH QUESTIONS AND VERIFIED A…
WGU: D027: Advanced Pathopharmacological
Foundations (2025) |COMPLETE GUIDE WITH
QUESTIONS AND VERIFIED ANSWERS|GET IT
100% CORRECT
Practice questions for this set
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Studied 7 terms
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Terms in this set (440)
- Brain shrinks dramatically; nerve cell death and
What are some physical tissue loss
changes from Alzheimer's - Cardinal signs: plaques (abnormal clusters of
dementia? protein fragments) and tangles (twisted strands of
another protein)
- There is no cure, but there are pharmacological
How is Alzheimer's and non-pharmacological treatments
treated? - Cholinesterase inhibitors
- Memantine (namenda)
- To treat symptoms related to memory, thinking,
What are cholinesterase
language, judgment, and other processes
inhibitors prescribed for?
- Helps delay or slow the worsening of symptoms
https://quizlet.com/989611754/wgu-d027-advanced-pathopharmacological-foundations-2025-complete-guide-with-questions-and-verified-answer… 1/16
,1/4/25, 5:25 PM WGU: D027: Advanced Pathopharmacological Foundations (2025) |COMPLETE GUIDE WITH QUESTIONS AND VERIFIED A…
- Prevent the breakdown of acetylcholine, a
What does chemical messenger that is important for learning
cholinesterase inhibitors and memory
do? - Supports communication among nerve cells by
keeping the acetylcholine high
What are some - Donepezil (aricept)
commonly prescribed - Galantamine (razadyne)
cholinesterase inhibitors? - Rivastigmine (exeleon)
Which cholinesterase - Donepezil (aricept)
inhibitor can be used for
all stages of Alzheimer's?
Which cholinesterase - Galantamine (razadyne)
inhibitor can be used for - Rivastigmine (exeleon)
mild-to-moderate stages
of Alzheimer's?
Which cholinesterase - Rivastigmine (exeleon)
inhibitor can be used for
mild-to-moderate
Alzheimer's and
Parkinson's?
What medication - Memantine (namenda) and donepezil (aricept)
combination is used to
treat moderate-to-severe
Alzheimer's?
- Prescribed to improve memory, attention, reason,
What is memantine language, and the ability to perform simple tasks
(namenda) used for? - Can be used alone or with other Alzheimer's
disease treatments
- Regulates the activity of glutamate, a chemical
involved in information processing, storage, and
How does memantine
retrieval
(namenda) work?
- Improves mental functioning and ability to perform
daily activities for some people
https://quizlet.com/989611754/wgu-d027-advanced-pathopharmacological-foundations-2025-complete-guide-with-questions-and-verified-answer… 2/16
, 1/4/25, 5:25 PM WGU: D027: Advanced Pathopharmacological Foundations (2025) |COMPLETE GUIDE WITH QUESTIONS AND VERIFIED A…
What is the difference in - Cholinesterase inhibitors prevent the breakdown
MOA between of acetylcholine, whereas memantine (namenda)
cholinesterase inhibitors regulates the activity of glutamate
and memantine
(namenda)?
- Also known as cerebellum attacks
- Degenerative disease of the nervous system
What is ataxia? - Many symptoms mimic those of being drunk (i.e.
slurred speech, stumbling, falling, and
incoordination)
- The damage caused to the cerebellum, the part of
the brain that is responsible for coordinating
What causes the
movements
symptoms of ataxia?
- Can also be caused by damage to part of the
spinal cord and nerves
- No treatment
- In some cases, treating the underlying causes (i.e.
stopping medications that cause ataxia)
What is the treatment for
- In other cases, it is a result from chicken pox or
ataxia?
other viral infections (likely to resolve on its own)
- Genetic causes/predisposed disposition is usually
chronic
- Genetic predisposition
What causes ataxia in the - Fragile X-Associated Tremor/Ataxia Syndrome
pediatric population? (FXTAS)
- Prader-Willie Syndrome
- A genetic condition inherited from parents which
results in various developmental problems
- Rare, but may be dangerous or life-threatening
What is Fragile X
- Present at birth and is a lifelong condition
syndrome (FXS)?
- Rarely requires lab testing or imaging
- Often linked to autism (1/3 do have autism)
- X-linked disorder
https://quizlet.com/989611754/wgu-d027-advanced-pathopharmacological-foundations-2025-complete-guide-with-questions-and-verified-answer… 3/16
WGU: D027: Advanced Pathopharmacological
Foundations (2025) |COMPLETE GUIDE WITH
QUESTIONS AND VERIFIED ANSWERS|GET IT
100% CORRECT
Practice questions for this set
Learn
Studied 7 terms
Nice work, you're crushing it
Continue studying in Learn
Terms in this set (440)
- Brain shrinks dramatically; nerve cell death and
What are some physical tissue loss
changes from Alzheimer's - Cardinal signs: plaques (abnormal clusters of
dementia? protein fragments) and tangles (twisted strands of
another protein)
- There is no cure, but there are pharmacological
How is Alzheimer's and non-pharmacological treatments
treated? - Cholinesterase inhibitors
- Memantine (namenda)
- To treat symptoms related to memory, thinking,
What are cholinesterase
language, judgment, and other processes
inhibitors prescribed for?
- Helps delay or slow the worsening of symptoms
https://quizlet.com/989611754/wgu-d027-advanced-pathopharmacological-foundations-2025-complete-guide-with-questions-and-verified-answer… 1/16
,1/4/25, 5:25 PM WGU: D027: Advanced Pathopharmacological Foundations (2025) |COMPLETE GUIDE WITH QUESTIONS AND VERIFIED A…
- Prevent the breakdown of acetylcholine, a
What does chemical messenger that is important for learning
cholinesterase inhibitors and memory
do? - Supports communication among nerve cells by
keeping the acetylcholine high
What are some - Donepezil (aricept)
commonly prescribed - Galantamine (razadyne)
cholinesterase inhibitors? - Rivastigmine (exeleon)
Which cholinesterase - Donepezil (aricept)
inhibitor can be used for
all stages of Alzheimer's?
Which cholinesterase - Galantamine (razadyne)
inhibitor can be used for - Rivastigmine (exeleon)
mild-to-moderate stages
of Alzheimer's?
Which cholinesterase - Rivastigmine (exeleon)
inhibitor can be used for
mild-to-moderate
Alzheimer's and
Parkinson's?
What medication - Memantine (namenda) and donepezil (aricept)
combination is used to
treat moderate-to-severe
Alzheimer's?
- Prescribed to improve memory, attention, reason,
What is memantine language, and the ability to perform simple tasks
(namenda) used for? - Can be used alone or with other Alzheimer's
disease treatments
- Regulates the activity of glutamate, a chemical
involved in information processing, storage, and
How does memantine
retrieval
(namenda) work?
- Improves mental functioning and ability to perform
daily activities for some people
https://quizlet.com/989611754/wgu-d027-advanced-pathopharmacological-foundations-2025-complete-guide-with-questions-and-verified-answer… 2/16
, 1/4/25, 5:25 PM WGU: D027: Advanced Pathopharmacological Foundations (2025) |COMPLETE GUIDE WITH QUESTIONS AND VERIFIED A…
What is the difference in - Cholinesterase inhibitors prevent the breakdown
MOA between of acetylcholine, whereas memantine (namenda)
cholinesterase inhibitors regulates the activity of glutamate
and memantine
(namenda)?
- Also known as cerebellum attacks
- Degenerative disease of the nervous system
What is ataxia? - Many symptoms mimic those of being drunk (i.e.
slurred speech, stumbling, falling, and
incoordination)
- The damage caused to the cerebellum, the part of
the brain that is responsible for coordinating
What causes the
movements
symptoms of ataxia?
- Can also be caused by damage to part of the
spinal cord and nerves
- No treatment
- In some cases, treating the underlying causes (i.e.
stopping medications that cause ataxia)
What is the treatment for
- In other cases, it is a result from chicken pox or
ataxia?
other viral infections (likely to resolve on its own)
- Genetic causes/predisposed disposition is usually
chronic
- Genetic predisposition
What causes ataxia in the - Fragile X-Associated Tremor/Ataxia Syndrome
pediatric population? (FXTAS)
- Prader-Willie Syndrome
- A genetic condition inherited from parents which
results in various developmental problems
- Rare, but may be dangerous or life-threatening
What is Fragile X
- Present at birth and is a lifelong condition
syndrome (FXS)?
- Rarely requires lab testing or imaging
- Often linked to autism (1/3 do have autism)
- X-linked disorder
https://quizlet.com/989611754/wgu-d027-advanced-pathopharmacological-foundations-2025-complete-guide-with-questions-and-verified-answer… 3/16
