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NURS 676 ADVANCED PHARMACOLOGY FINAL EXAM REVIEW / QUESTIONS AND CORRECT ANSWERS 2023/2024 GRADED A+.

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NURS 676 ADVANCED PHARMACOLOGY FINAL EXAM REVIEW / QUESTIONS AND CORRECT ANSWERS 2023/2024 GRADED A+. 2 / 6 1. Why are nitrate-free periods every 24 hours necessary for the patient onnitroglycerin therapy?: To inhibit the development of tolerance 2. What does a low level of thyroid-stimulating hormone indicate?: Hyper-throidism 3. What would be the best option to treat a newly diagnosed patient with a lowTSH level with?: Propanolol (Inderal) 4. Spironoaldactone (Aldactone) has what mechanism of action (MOA)?: Al-dosterone antagonist 5. Heparin exertsitstherapeutic action by what?: Upregulating the activity of oneof the body's natural anticoagulant molecules, antithrombin III 6. What physiologic action happens when the offending drug is administeredduring an anaphylactic reaction.: Mast cells liberate large doses of histamine. 7. What are two systemic psoriasis medications?: Photo-therapy and topicalcorticosteroids 8. What is the first choice of drug therapy for the majority of patients withuncomplicated stage I hypertension?: Thiazide diuretics 9. What is the effect of cardiac glycosides?: Digitalis glycosides have a negativechronotropic effect on the cardiac muscle cells. 10. Amenorrhea is the most common side effect of which birth control med-ication?: Medroxyprogesterone (Depo-Provera) 11. What is an anti-hypertensive agent which competes with epinephrine foravailable betareceptor sites?: Atenolol (Tenormin) 12. What type of action does nitrates have on the body?: Reduction in systemicvenous tone. 13. What is the recommended level of low-density lipoprotein cholesterol(LDL) for patients with known coronary artery disease?: 100mg/dl or less. 14. What is the MOA of group IV anti-dysrhythmia drugs?: Depressing phase 4depolarization and lengthening phases 1 and 2 repolarization. 15. Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-establish eumetabolic state in a patient with Graves'disease?: Anti-thyroid drugs. 16. Which type of diuretic would be used for a stage I hypertension in a patientwith renal insufficiency?: Loop diuretic.

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NURS 676 ADVANCED PHARMACOLOGY
FINAL EXAM REVIEW / QUESTIONS AND
CORRECT ANSWERS 2024/2025GRADED A+.


Why hare hnitrate-free hperiods hevery h24 hhours hnecessary hfor hthe hpatient hon hnitroglycerin
h therapy? h- hANS-To hinhibit hthe hdevelopment hof htolerance


What hdoes ha hlow hlevel hof hthyroid-stimulating hhormone hindicate? h- hANS-Hyperthroidism


What hwould hbe hthe hbest hoption hto htreat ha hnewly hdiagnosed hpatient hwith ha hlow hTSH hlevel
h with? h- hANS-Propanolol h(Inderal)


Spironoaldactone h(Aldactone) hhas hwhat hmechanism hof haction h(MOA)? h- hANS-Aldosterone
h antagonist


Heparin hexerts hits htherapeutic haction hby hwhat? h- hANS-Upregulating hthe hactivity hof hone hof
h the hbody's hnatural hanticoagulant hmolecules, hantithrombin hIII


What hphysiologic haction hhappens hwhen hthe hoffending hdrug his hadministered hduring han
h anaphylactic hreaction. h- hANS-Mast hcells hliberate hlarge hdoses hof hhistamine.


What hare htwo hsystemic hpsoriasis hmedications? h- hANS-Photo-therapy hand htopical
h corticosteroids


What his hthe hfirst hchoice hof hdrug htherapy hfor hthe hmajority hof hpatients hwith huncomplicated
h stage hI hhypertension? h- hANS-Thiazide hdiuretics

, What his hthe heffect hof hcardiac hglycosides? h- hANS-Digitalis hglycosides hhave ha hnegative
h chronotropic heffect hon hthe hcardiac hmuscle hcells.


Amenorrhea his hthe hmost hcommon hside heffect hof hwhich hbirth hcontrol hmedication? h- hANS-
Medroxyprogesterone h(Depo-Provera)


What his han hanti-hypertensive hagent hwhich hcompetes hwith hepinephrine hfor havailable hbeta-
receptor hsites? h- hANS-Atenolol h(Tenormin)


What htype hof haction hdoes hnitrates hhave hon hthe hbody? h- hANS-Reduction hin hsystemic
h venous htone.


What his hthe hrecommended hlevel hof hlow-density hlipoprotein hcholesterol h(LDL) hfor hpatients
h with hknown hcoronary hartery hdisease? h- hANS-100mg/dl hor hless.


What his hthe hMOA hof hgroup hIV hanti-dysrhythmia hdrugs? h- hANS-Depressing hphase h4
h depolarization hand hlengthening hphases h1 hand h2 hrepolarization.


Which hdrug htherapy hshould hbe hused hto hlower hthe hserum hconcentration hof hthyroid
h hormones hand hre-establish heumetabolic hstate hin ha hpatient hwith hGraves' hdisease? h- hANS-
Anti-thyroid hdrugs.


Which htype hof hdiuretic hwould hbe hused hfor ha hstage hI hhypertension hin ha hpatient hwith hrenal
h insufficiency? h- hANS-Loop hdiuretic.


What hdrug hshould hbe hconsidered has hfirst-line htherapy hfor ha hclient hwith hhypertension hand
h heart hfailure? h- hANS-Enalapril h(Vasotec)


Which hdrug his hconsidered hsafe hfor hhypertension htreatment hduring hpregnancy? h- hANS-
Methyldopa h(Aldomet)
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