Pharmacology Psychiatric Mental
Health Nurse Practitione Questions and
Correct Verified Answers r
What are the five factors that influence absorption?
✓ Gastric emptying
✓ Time of contact with intestinal wall
✓ Bowel perfusion
✓ Food
✓ Formation of non-absorbable complexes
Explain the hepatic first pass.
✓ Part of the drug is metabolized by the liver before it reaches the blood.
Explain bioavailability.
✓ Percentage of administered drug that reaches systemic circulation.
Name the 3 highly water-soluble drugs.
✓ Lithium, Amisulpride, Paliperidone
What are the 7 inhibitors of CYP?
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, Top Mark Questions and Correct Verified Answers
✓ Paroxetine, Fluoxetine, Fluvoxamine, Fluconazole, Ciprofloxacin, Ritonavir,
Grapefruit juice
What are the 6 inducers of CYP?
✓ Carbamazepine, Phenytoin, Phenobarbital, Primidone, smoking, St-John's Wort
What are the 6 factors that influence pharmacokinetics?
✓ Age, pregnancy, obesity, sexe, comorbidities, genetics
Explain the half-life.
✓ The time it takes for the concentration of a drug to be reduced by 50%
What are the 11 indications for TDM.
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