Test Bank For Molecular Cell CellBy Harvey Lodish, Angelika AmonNEWEST EDITION a+

© Garland Science 2025
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,
, TEST BANK FOR MOLECULAR BIOLOGY OF THE CELL,
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NINTH EDITION ki ki ki




1 Imagine a protein that has been engineered to contain a nuclear localization signal, a nuclear
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export signal, a C-terminal peroxisomal targeting sequence, and a canonical endoplasmic reticulum
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(ER) signal sequence. With all of these signals, where would you expect to find the protein after its
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synthesis?
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A. Cytosol
B. Nucleus
C. Shuttling between the cytosol and the nucleus ki ki ki ki ki ki




D. Peroxisomes
E. Endoplasmic reticulum ki




2 Consider a human cell such as a hepatocyte. Which of the following
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compartments occupies a larger volume in the cell?
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A. Cytosol
B. Nucleus
C. Endoplasmic reticulum ki




D. Mitochondria
E. Peroxisomes


3 Consider a human liver hepatocyte. Among the following membranes, which one has the
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largest total area?
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A. Plasma membrane ki




B. Nuclear inner membrane ki ki




C. Mitochondrial outer membrane ki ki




D. Rough ER membrane ki ki




E. Smooth ER membrane ki ki




4 Consider two cells, A and B. Both are approximately spherical, but cell A is a bacterium
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with a diameter of only about 1 µm, while the diameter of the eukaryotic cell B is about 10 µm.
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, If the plasma membrane in the eukaryotic cell comprises only about 2% of the total cell membrane,
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which cell has a higher ratio of total cell membrane to volume? Write down A or B as your
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ki answer. k i




5 Indicate whether the location of each of the following is topologically equivalent to the ki ki ki ki ki ki ki ki ki ki ki ki ki




cytosol (C) or the extracellular space (E). Your answer would be a five-letter string composed of
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letters C and E only, e.g. CCECE.
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( ) Ribosomes ki




ki ( )
k i Chromatin
( ) Lysosomal hydrolaseski ki




k i ( ) Calcium ions in the ER ki ki ki ki ki




ki ( ) Peroxisomal catalase ki ki




6 Indicate whether each of the following transport processes occurs via the mechanisms ki ki ki ki ki ki ki ki ki ki ki




described as gated transport (G), transmembrane transport (T), or vesicular transport (V). Your
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answer would be a five-letter string composed of letters G, T, and V only, e.g. VTTTG.
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( ) Import into nucleuski ki ki




( ) Exportfrom nucleus
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( ) Import into mitochondria
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k ( ) Return from Golgi to
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ki ER ( ) Return from ER to k i ki ki ki ki




cytosol
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7 Indicate true (T) and false (F) statements below regarding the k i k i k i k i k i k i k i k i k i




compartmentalization of cells. Your answer would be a four-letter string composed of letters T
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and F only, e.g. TTTF.
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( ) Almost all eukaryotic cells have plastids, but only plant cells have
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capable of photosynthesis.
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( ) The perinuclear space is topologically equivalent to the extracellular space.
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( ) The mitochondria and chloroplasts are thought to have evolved by invagination and
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pinching off from the plasma membrane of the ancient eukaryotic cell.
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( ) All organelles in a eukaryotic cell can be constructed de novo, which means that the
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information to construct them is encoded in the genome.
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8 Fill in the blank in the following paragraph. DO NOT use abbreviations.
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“A significant fraction of total membrane area in a eukaryotic cell
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encloses the lumen of the ..., which forms an extended
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