f f
MODERN BLOOD BA f f
NKING & TRANSFUS
f f
ION PRACTICES 6TH
f f f
EDITION DENISE M.
f f f
HARMENING
,TEST BANK FOR
f f
MODERN BLOOD BANKING
f f f
& TRANSFUSION PRACTICES
f f
6TH EDITION
f
DENISE M. HARMENING
f f
, Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
f f f f f f f f f f
MultiplefChoice
Identifyfthefchoicefthatfbestfcompletesfthefstatementforfanswersfthefquestion.
f 1.f Whichfmetabolicfpathwayfisfresponsiblefforfgeneratingf90%foffthefATPfforfthefRBC?
a. Pentosefphosphatefshunt c. Glycolysis
b. Luebering-Rapoportfshunt d.f Methemoglobinfreductase
f
2.f Afunitfoffbloodfwasfreturnedftofthefbloodfbankfbeforefitfwasfspiked.fApparentlyfthefpatient’sfIVffailed.fThef
unitfoffbloodfwasfoutsidefthefbloodfbankfforf35fminutes.fWhichfoffthefstatementsfbelowfisfmostfaccurate?
a. Thefunitfoffbloodfshouldfbefdiscardedfimmediately.
b. Thefunitfoffbloodfcanfbefreturnedftofinventory.
c. Thefunitfoffbloodfmustfbeftransfusedfwithinf4fhoursforfbefdiscardedfatfthefendfoffthatftime.
d. Thefunitfoffbloodfmustfbeftransfusedfwithf24fhours.
f 3.f Whatfisfthefaveragefdiameterfoffafplatelet?
a. 5ftof10fµm c. 1ftof2fµm
b. 2ftof4fµm d.fff 4ftof6fµm
f 4.fInfthefnormalfhemoglobin-
oxygenfdissociationfcurve,fwhatfpercentagefoffoxygenfisfreleasedftoftheftissuesfwhenfPO2faveragesf40fmmfH
g?
a. 75% c. 100%
b.fff 25% d.f 50%
f 5.f Whatffactorsfarefknownftofinfluencefplateletfmetabolismfandffunction?
a. Storageftemperature c. Plateletfcount
b. InitialfpH d.f Allfoffthefabove
f
6.fWhichfofftheffollowingfredfbloodfcellfmorphologiesfmayfbefpresentfonfthefperipheralfbloodfsmearfasfafresul
tfofflossfoffRBCfmembrane?
a. Spherocytes c. Burrfcells
b. Targetfcells d.f Schistocytes
f 7.f Whatfdoesftheftermfautologousftransfusionfreferfto?
a. Afparentfdonatingfbloodfforfhisforfherfchild
b. Anfindividualfdonatingfbloodfforfaffriend
c. Anfindividualfdonatingfbloodfforfafrelative
d. Anfindividualfdonatingfbloodfforfhisforfherfownftransfusion
f 8.f Whatfisfthefprimaryffunctionfoffhemoglobin?
a. Ironfmetabolism c. Oxygenftransport
b. Porphyrinfsynthesis d.f Signalftransduction
f 9.f Allfofftheffollowingfareasfoffredfbloodfcellfbiologyfarefcrucialfforfnormalferythrocytefsurvivalf except:
a. Cellularfmetabolism. c. SitefoffthefABOfantigenfattachment.
b. RBCfmembrane. d.f Hemoglobinfstructure.
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, f ff 10.f WhatfisfthefcorrectfbiochemicalfcompositionfoffthefRBCfmembrane?
a. 52%fprotein,f40%flipid,f8%fcarbohydrate
b. 40%fprotein,f8%flipid,f52%fcarbohydrate
c. 8%fprotein,f52%flipid,f40%fcarbohydrate
d. 8%flipid,f40%fcarbohydrate,f52%fprotein
f fff 11.f Allfofftheffollowingfbiochemicalfchangesfarefassociatedfwithflossfoffredfbloodfcellfviabilityfuponfstorage
except:
a. DecreasedfpH. c. IncreasedfATPflevel.
b. Lossfoffredfbloodfcellffunction. d.f Decreasedfglucosefconsumption.
f ff 12.f Whichfredfbloodfcellfpreservativefhasfafstorageftimefoff35fdays?
a. ACD c. AS-1
b. CPDA-1 d.fff CPD
f ff 13.f ThefRBCfmembranefisfrelativelyfpermeableftofallfofftheffollowingfexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.f Water.
f
ff 14.fWhatfpercentagefoffplateletsfisfsequesteredfinfthefspleenfasffunctionalfreservefafterfbeingfreleasedffromf
thefbonefmarrow?
a. 30% c. 10%
b.fff 50% d.fff 25%
f ff 15.f Whatfisfthefmajorfbiochemicalfconsiderationfinfplateletfstorage?
a. Glucosefmetabolism c. Productionfoffcarbonfdioxide
b. Oxygenfsupply d.f RegulationfoffpH
f ff 16.fWhatfwouldfthefhemoglobin-
oxygenfdissociationfcurvefdepictfinfafpatientfexhibitingfclinicalfsignsfoffalkalosis?
a. Normal c. Shiftftofthefright
b. Shiftftofthefleft d.f Nonefoffthefabove
f ff 17.f Namefthefmainflipidfcomponentsfoffafredfbloodfcellfmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.f GlycophorinfA
f ff 18.f ThefABOfbloodfgroupsfwerefdiscoveredfinf1901fbyfwhom?
a. CharlesfDrew c. LoutitfandfMollison
b. KarlfLandsteiner d.f EdwardfLindeman
f
19.fAfstandingforderfoffplateletsfwasfshippedftofyourffacilityfbyfyourfsupplier.fItfwasfinadvertentlyfleftfinfthe
ff
fcornerfoffthefdepartmentfuntilfdiscoveredf36fhoursflater.fWhatfwouldfthefappropriatefactionfbefforfthefbloodfban
ker?
a. Ifftheftemperaturefinfthefboxfwasf22f+/-
f2°CfandfthefplateletfswirlfseemedfOK,fitfwouldfbefOKftofacceptfthefunitfintofinventory.
b. Thefplateletsfhaveffallenfoutsidefthefsupplier’sfqualityfassurance.fThefunitfshouldfbe
discardedfbecausefthefpHfhasfprobablyfdroppedftooflowfandfplateletfactivationfhasfbeenfcompromised.
c. Ifftheftemperaturefwasf1°Cftof6°CfandfthefplateletfswirlfseemedfOK,fitfwouldfbefOKfto
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