ANCC AGPCNP PRACTICE QUESTIONS WITH
CORRECT ANSWERS
AnA18-year-
oldAfemaleApatientAisAbeingAfollowedAupAforAacneAbyAtheAnurseApractitioner.ADuringAtheAfacialAexam,Apap
ulesAandApustulesAareAnotedAmostlyAonAtheAforeheadAandAtheAchinAareas.ATheApatientAhasAbeenAusingAover
-the-
counterAtopicalAantibioticAgelsAandAmedicatedAsoapAdailyAforA6AmonthsAwithoutAmuchAimprovement.ATheA
nurseApractitionerAwillArecommend:
a.AIsotretinoinA(Accutane)
b.ATetracyclineA(Sumycin)
c.AClindamycinAtopicalAsolutionA(Cleocin-AT)
d.AMinoxidilA(Rogaine)A-AcorrectAanswer-b.ATetracyclineA(Sumycin)
First-lineAtreatmentAforAacneAvulgarisAincludesAover-the-
counterAmedicatedAsoapAandAwaterAwithAtopicalAantibioticAgels.ATheAnextAstepAinAtreatmentAwouldAbeAtheA
initiationAofAoralAtetracycline.
AAyoungAadultApresentsAforAreassessmentAofAuncontrolledAasthmaAsymptoms.ATheApatientAisAcurrentlyAtak
ingAanAinhaledAshort-actingAbeta2-
agonistA(SABA)AasAneededAandAreportsAdaytimeAsymptomsAmoreAthanA3Adays/week,AbutAnotAdaily,AandAni
ghttimeAawakeningsA4AtoA5Atimes/week.ATheApatient'sAforcedAexpiratoryAvolumeA(FEV1)AisA80%AofApredi
cted.ATheAnurseApractitionerAupgradesAtheApatientAtoAtheAnextAstageAofAtreatment,AwhichAincludes:
a.ABudesonideAwithAformoterol
b.ABudesonideAwithAmontelukast
c.ACromolynAorAnedocromil
d.AFluticasoneAwithAsalmeterolA-AcorrectAanswer-a.ABudesonideAwithAformoterol.
TheApatientAhasAmovedAfromAstepA2AtoAstepA3AonAtheAasthmaAclassificationAscale.ATherefore,AaAlow-
doseAinhaledAcorticosteroidA(ICS)AplusAlong-actingAbeta-
agonistA(LABA)AsuchAasAbudesonideAwithAformoterolAisAanAappropriateAstartingApoint.AFluticasoneAwithAs
almeterolAisAprescribedAifAtheApatientAisAatAstepA4;AbudesonideAwithAmontelukastAisAanAalternative.ACromo
lynAandAnedocromilAhaveAbeenAdiscontinuedAinAtheAUnitedAStates.
,WhichAofAtheAfollowingAdrugsAcanAincreaseAtheAriskAofAbleedingAinApatientsAwhoAareAreceivingAanticoagul
ationAtherapyAwithAwarfarinAsodiumA(Coumadin)?
a.ATrimethoprim-sulfamethoxazoleA(BactrimADS)
b.ACarafateA(Sucralfate)
c.ALosartanA(Cozaar)
d.AFurosemideA(Lasix)A-AcorrectAanswer-a.ATrimethoprim-sulfamethoxazoleA(BactrimADS).
WarfarinAsodiumA(Coumadin)AinteractsAwithABactrimAandAwillAincreaseAtheAriskAofAbleeding;Atherefore,Ac
oncurrentAuseAisAcontraindicated.
AA22-year-oldAwomanAisAgoingAonAaA5-
dayAcruiseAforAherAhoneymoon.ASheAreportsAaAhistoryAofAsevereAmotionAsickness.AWhichAofAtheAfollowing
AmedicinesAcanAbeAprescribedAforAmotionAsickness?
a.ADimenhydrinateA(Dramamine)
b.AMetoclopramideA(Reglan)
c.AOndansetronA(Zofran)
d.AScopolamineApatchA(TransdermAScop)A-AcorrectAanswer-d.AScopolamineApatchA(TransdermAScop)
ScopolamineApatchA(TransdermAScop)AisAaAprescriptionAmedicineAthatAisAusedAforAmotion/seaAsickness.AIt
AisAaAsmall,AcircularApatchAthatAisAplacedAbehindAtheAearAandAisAeffectiveAforA3Adays.AAdviseAtheApatientAto
AapplyAitA4AhoursAbeforeAtheAtripAtoAbeAeffective.ABecauseAtheAquestionAisAaskingAaboutAaA"prescribed"Ame
dication,AanAover-the-
counterA(OTC)Amedicine,AsuchAasADramamine,AisAanAincorrectAresponse.AZofranAisAindicatedAforAcancer-
relatedAnauseaAandAvomitingA(chemotherapy,Aradiation,Asurgery).
TheAnurseApractitionerAisAcompletingAaAhealthAassessmentAonAaA15-year-
oldAfemaleApatientAwhoAisAinAtheAofficeAforAherAannualAphysical.ATheApatientAreportsAfeelingsAofAhopeless
nessAandAsadnessAforAseveralAmonths,AnoAhistoryAofAsuicidalAideations,AandAaAstruggleAwithAanorexia.AThe
ApatientAscoresAanA11AonABeck'sADepressionAInventory.AWhichAantidepressantAwillAtheAnurseApractitionerA
prescribe?
a.ASertralineA(Zoloft)
,b.ALithiumAcarbonateA(Eskalith)
c.ABupropionA(Wellbutrin)
d.AEscitalopramA(Lexapro)A-AcorrectAanswer-d.AEscitalopramA[Lexapro]
EscitalopramAisAaAsafeAantidepressantAforAanAadolescentAwhoAhasAsevereAdepressionAandAnoAhistoryAofAsui
cidalAideations.ASertralineAisAnotAaAsafeAoptionAforApatientsAyoungerAthanA24AyearsAofAageAbecauseAofAincr
easedAriskAofAsuicidalAideation.ABupropionAisAanAatypicalAantidepressantAandAisAnotAaAfirst-
lineAtherapyAforAdepression.AItAisAcontraindicatedAinApatientsAwithAanorexiaAnervosa.ALithiumAisAindicated
AforApatientsAwithAbipolarAdisorder.
WhichAinitialAtreatmentAwillAtheAnurseApractitionerAprescribeAtoAaA23-year-
oldAfemaleAallergicAtoAsulfaAdrugsAwhoAisAdiagnosedAwithAacuteAcystitis?
a.ACephalexinA(Keflex)A500AmgABIDA×A5Adays
b.ACiprofloxacinA(Cipro)A250AmgABIDA×A3Adays
c.ANitrofurantoinA(Macrobid)A100AmgABIDA×A5Adays
d.AAmoxicillinA500AmgABIDA×A5AdaysA-AcorrectAanswer-
c.ANitrofurantoinA(Macrobid)A100AmgABIDA×A5Adays
NitrofurantoinAcanAbeAsafelyAadministeredAtoAaApatientAwithAaAsulfaAallergyAtoAtreatAacuteAcystitisAandAisAt
heAfirstAlineAofAtreatment.ACephalexinAandAamoxicillinAareAbeta-
lactamAantibioticsAthatAcanAbeAprescribedAforAaApatientAwhoAhasAanAallergyAtoAsulfaAandAnitrofurantoin.AAA
fluoroquinolone,AsuchAasAciprofloxacin,AisArecommendedAforAaApatientAwhoAisAallergicAtoAsulfaAandAbeta-
lactamAdrugsAorAhasAaAsulfaAallergyAandAaAknownAresistanceAtoAbeta-lactamAantibiotics.
AA68-year-oldApatientArecentlyAprescribedAcaridopa-
levodopaA(Sinemet)AtellsAtheAnurseApractitionerAthatAheAhasAbeenAbloatedAandAexperiencingAdifficultyAwit
hAbowelAmovements.AWhichAmedicationAwillAtheAnurseApractitionerAconsiderAincorporatingAintoAtheAtreat
mentAplan?
a.ASenna
b.AMethylnaltrexone
c.AMagnesiumAcitrate
d.APolyethyleneAglycolA-AcorrectAanswer-d.APolyethyleneAglycol
, Levodopa,AanAantiparkinsonianAdrug,AcanAcauseAconstipationAinAanAolderApatient.ATheAfirst-
lineAtreatmentAforAtheApatient'sAconstipationAisAosmoticAlaxativesAsuchAasApolyethyleneAglycol.ASennaAisAa
AstimulantAlaxativeAthatAisAaAsecond-
lineAtreatmentAforAconstipationAinAanAolderAadult.AMethylnaltrexoneAisAaAperipherallyAactingAmu-
opioidAantagonistAthatAactsAonAtheAgastrointestinalAtractAtoAdecreaseAopioid-
inducedAconstipation.AMagnesium-
basedAlaxativesA(e.g.,AmagnesiumAcitrate)AtakenAoverAtheAlongAtermAshouldAbeAavoidedAbecauseAofAtheApo
tentialAofAtoxicity.
AApatientArecentlyAreturnedAfromAaAtripAtoAAfricaAandAisAexperiencingA10AtoA12AlooseAstoolsAeveryAday.AT
heApatientAtakesAmetforminAeveryAmorningAandAotherwiseAisAinAgoodAhealth.AWhichAmedicationAwillAtheA
nurseApractitionerAprescribeAtoAtreatAtheAdiarrhea?
a.ALevofloxacinAdaily
b.AOfloxacinABID
c.ATrimethoprim-sulfamethoxazoleABID
d.ACiprofloxacinAinAaAsingleAdoseA-AcorrectAanswer-d.ACiprofloxacinAinAaAsingleAdose
TheApatientAmostAlikelyAhasAtraveler'sAdiarrhea,AgivenAtheAhistoryAofAaArecentAreturnAfromAanotherAcountr
y.ATheApatient'sAtreatmentAshouldAbeAbasedAonAfunctionalAimpactAofAsymptomsAandAnotAfrequencyAofAsym
ptoms,AwhichAisAnotAindicatedAinAtheAquestion.ATheApatientAlikelyAhasAmoderateAacuteAtraveler'sAdiarrhea,A
whichAcanAbeAtreatedAwithAloperamideAasAmonotherapyAorAwithAadjunctiveAantibioticAtherapy.ATheApatient
AisAtakingAmetforminAdailyAforAdiabetes,AsoAriskAofAprecipitatingAhypoglycemiaAisAlowerAthanAwithAotherA
oralAantidiabeticAagents.ABecauseAitAcanAbeAgivenAinAaAsingleAdose,AciprofloxacinAwouldAbeAtheAappropriat
eAchoiceAforAreducingAexposureAandAmicrobiomeAcolonizationAdisruption.ALevofloxacinAandAofloxacinAre
quireAoneAtoAthreeAdoses.ATrimethoprim-
sulfamethoxazoleAisAaAsulfonamideAandAwouldAbeAappropriateAtreatmentAforAcyclosporiasisAbutAnotAgiardi
asis,AwhichAisAtheAmostAcommonAparasiticAcauseAofAtraveler'sAdiarrhea.
AApatientAnewlyAdiagnosedAwithAdiabetesAreportsAsevereAhivesAandAswollenAlipsAafterAtakingABactrimAforA
aAbladderAinfectionA2AmonthsAago.AWhichAofAtheAfollowingAstatementsAisAcorrect?
a.ATheApatientAcannotAtakeAanyApillsAinAtheAsulfonylureaAclass
b.ATheApatientAcanAtakeAsomeAofAtheApillsAinAtheAsulfonylureaAclass
c.ATheApatientAcanAtakeAanyAofAtheApillsAinAtheAsulfonylureaAclass
d.ANoneAofAtheAaboveA-AcorrectAanswer-c.ATheApatientAcanAtakeAanyAofAtheApillsAinAtheAsulfonylureaAclass
CORRECT ANSWERS
AnA18-year-
oldAfemaleApatientAisAbeingAfollowedAupAforAacneAbyAtheAnurseApractitioner.ADuringAtheAfacialAexam,Apap
ulesAandApustulesAareAnotedAmostlyAonAtheAforeheadAandAtheAchinAareas.ATheApatientAhasAbeenAusingAover
-the-
counterAtopicalAantibioticAgelsAandAmedicatedAsoapAdailyAforA6AmonthsAwithoutAmuchAimprovement.ATheA
nurseApractitionerAwillArecommend:
a.AIsotretinoinA(Accutane)
b.ATetracyclineA(Sumycin)
c.AClindamycinAtopicalAsolutionA(Cleocin-AT)
d.AMinoxidilA(Rogaine)A-AcorrectAanswer-b.ATetracyclineA(Sumycin)
First-lineAtreatmentAforAacneAvulgarisAincludesAover-the-
counterAmedicatedAsoapAandAwaterAwithAtopicalAantibioticAgels.ATheAnextAstepAinAtreatmentAwouldAbeAtheA
initiationAofAoralAtetracycline.
AAyoungAadultApresentsAforAreassessmentAofAuncontrolledAasthmaAsymptoms.ATheApatientAisAcurrentlyAtak
ingAanAinhaledAshort-actingAbeta2-
agonistA(SABA)AasAneededAandAreportsAdaytimeAsymptomsAmoreAthanA3Adays/week,AbutAnotAdaily,AandAni
ghttimeAawakeningsA4AtoA5Atimes/week.ATheApatient'sAforcedAexpiratoryAvolumeA(FEV1)AisA80%AofApredi
cted.ATheAnurseApractitionerAupgradesAtheApatientAtoAtheAnextAstageAofAtreatment,AwhichAincludes:
a.ABudesonideAwithAformoterol
b.ABudesonideAwithAmontelukast
c.ACromolynAorAnedocromil
d.AFluticasoneAwithAsalmeterolA-AcorrectAanswer-a.ABudesonideAwithAformoterol.
TheApatientAhasAmovedAfromAstepA2AtoAstepA3AonAtheAasthmaAclassificationAscale.ATherefore,AaAlow-
doseAinhaledAcorticosteroidA(ICS)AplusAlong-actingAbeta-
agonistA(LABA)AsuchAasAbudesonideAwithAformoterolAisAanAappropriateAstartingApoint.AFluticasoneAwithAs
almeterolAisAprescribedAifAtheApatientAisAatAstepA4;AbudesonideAwithAmontelukastAisAanAalternative.ACromo
lynAandAnedocromilAhaveAbeenAdiscontinuedAinAtheAUnitedAStates.
,WhichAofAtheAfollowingAdrugsAcanAincreaseAtheAriskAofAbleedingAinApatientsAwhoAareAreceivingAanticoagul
ationAtherapyAwithAwarfarinAsodiumA(Coumadin)?
a.ATrimethoprim-sulfamethoxazoleA(BactrimADS)
b.ACarafateA(Sucralfate)
c.ALosartanA(Cozaar)
d.AFurosemideA(Lasix)A-AcorrectAanswer-a.ATrimethoprim-sulfamethoxazoleA(BactrimADS).
WarfarinAsodiumA(Coumadin)AinteractsAwithABactrimAandAwillAincreaseAtheAriskAofAbleeding;Atherefore,Ac
oncurrentAuseAisAcontraindicated.
AA22-year-oldAwomanAisAgoingAonAaA5-
dayAcruiseAforAherAhoneymoon.ASheAreportsAaAhistoryAofAsevereAmotionAsickness.AWhichAofAtheAfollowing
AmedicinesAcanAbeAprescribedAforAmotionAsickness?
a.ADimenhydrinateA(Dramamine)
b.AMetoclopramideA(Reglan)
c.AOndansetronA(Zofran)
d.AScopolamineApatchA(TransdermAScop)A-AcorrectAanswer-d.AScopolamineApatchA(TransdermAScop)
ScopolamineApatchA(TransdermAScop)AisAaAprescriptionAmedicineAthatAisAusedAforAmotion/seaAsickness.AIt
AisAaAsmall,AcircularApatchAthatAisAplacedAbehindAtheAearAandAisAeffectiveAforA3Adays.AAdviseAtheApatientAto
AapplyAitA4AhoursAbeforeAtheAtripAtoAbeAeffective.ABecauseAtheAquestionAisAaskingAaboutAaA"prescribed"Ame
dication,AanAover-the-
counterA(OTC)Amedicine,AsuchAasADramamine,AisAanAincorrectAresponse.AZofranAisAindicatedAforAcancer-
relatedAnauseaAandAvomitingA(chemotherapy,Aradiation,Asurgery).
TheAnurseApractitionerAisAcompletingAaAhealthAassessmentAonAaA15-year-
oldAfemaleApatientAwhoAisAinAtheAofficeAforAherAannualAphysical.ATheApatientAreportsAfeelingsAofAhopeless
nessAandAsadnessAforAseveralAmonths,AnoAhistoryAofAsuicidalAideations,AandAaAstruggleAwithAanorexia.AThe
ApatientAscoresAanA11AonABeck'sADepressionAInventory.AWhichAantidepressantAwillAtheAnurseApractitionerA
prescribe?
a.ASertralineA(Zoloft)
,b.ALithiumAcarbonateA(Eskalith)
c.ABupropionA(Wellbutrin)
d.AEscitalopramA(Lexapro)A-AcorrectAanswer-d.AEscitalopramA[Lexapro]
EscitalopramAisAaAsafeAantidepressantAforAanAadolescentAwhoAhasAsevereAdepressionAandAnoAhistoryAofAsui
cidalAideations.ASertralineAisAnotAaAsafeAoptionAforApatientsAyoungerAthanA24AyearsAofAageAbecauseAofAincr
easedAriskAofAsuicidalAideation.ABupropionAisAanAatypicalAantidepressantAandAisAnotAaAfirst-
lineAtherapyAforAdepression.AItAisAcontraindicatedAinApatientsAwithAanorexiaAnervosa.ALithiumAisAindicated
AforApatientsAwithAbipolarAdisorder.
WhichAinitialAtreatmentAwillAtheAnurseApractitionerAprescribeAtoAaA23-year-
oldAfemaleAallergicAtoAsulfaAdrugsAwhoAisAdiagnosedAwithAacuteAcystitis?
a.ACephalexinA(Keflex)A500AmgABIDA×A5Adays
b.ACiprofloxacinA(Cipro)A250AmgABIDA×A3Adays
c.ANitrofurantoinA(Macrobid)A100AmgABIDA×A5Adays
d.AAmoxicillinA500AmgABIDA×A5AdaysA-AcorrectAanswer-
c.ANitrofurantoinA(Macrobid)A100AmgABIDA×A5Adays
NitrofurantoinAcanAbeAsafelyAadministeredAtoAaApatientAwithAaAsulfaAallergyAtoAtreatAacuteAcystitisAandAisAt
heAfirstAlineAofAtreatment.ACephalexinAandAamoxicillinAareAbeta-
lactamAantibioticsAthatAcanAbeAprescribedAforAaApatientAwhoAhasAanAallergyAtoAsulfaAandAnitrofurantoin.AAA
fluoroquinolone,AsuchAasAciprofloxacin,AisArecommendedAforAaApatientAwhoAisAallergicAtoAsulfaAandAbeta-
lactamAdrugsAorAhasAaAsulfaAallergyAandAaAknownAresistanceAtoAbeta-lactamAantibiotics.
AA68-year-oldApatientArecentlyAprescribedAcaridopa-
levodopaA(Sinemet)AtellsAtheAnurseApractitionerAthatAheAhasAbeenAbloatedAandAexperiencingAdifficultyAwit
hAbowelAmovements.AWhichAmedicationAwillAtheAnurseApractitionerAconsiderAincorporatingAintoAtheAtreat
mentAplan?
a.ASenna
b.AMethylnaltrexone
c.AMagnesiumAcitrate
d.APolyethyleneAglycolA-AcorrectAanswer-d.APolyethyleneAglycol
, Levodopa,AanAantiparkinsonianAdrug,AcanAcauseAconstipationAinAanAolderApatient.ATheAfirst-
lineAtreatmentAforAtheApatient'sAconstipationAisAosmoticAlaxativesAsuchAasApolyethyleneAglycol.ASennaAisAa
AstimulantAlaxativeAthatAisAaAsecond-
lineAtreatmentAforAconstipationAinAanAolderAadult.AMethylnaltrexoneAisAaAperipherallyAactingAmu-
opioidAantagonistAthatAactsAonAtheAgastrointestinalAtractAtoAdecreaseAopioid-
inducedAconstipation.AMagnesium-
basedAlaxativesA(e.g.,AmagnesiumAcitrate)AtakenAoverAtheAlongAtermAshouldAbeAavoidedAbecauseAofAtheApo
tentialAofAtoxicity.
AApatientArecentlyAreturnedAfromAaAtripAtoAAfricaAandAisAexperiencingA10AtoA12AlooseAstoolsAeveryAday.AT
heApatientAtakesAmetforminAeveryAmorningAandAotherwiseAisAinAgoodAhealth.AWhichAmedicationAwillAtheA
nurseApractitionerAprescribeAtoAtreatAtheAdiarrhea?
a.ALevofloxacinAdaily
b.AOfloxacinABID
c.ATrimethoprim-sulfamethoxazoleABID
d.ACiprofloxacinAinAaAsingleAdoseA-AcorrectAanswer-d.ACiprofloxacinAinAaAsingleAdose
TheApatientAmostAlikelyAhasAtraveler'sAdiarrhea,AgivenAtheAhistoryAofAaArecentAreturnAfromAanotherAcountr
y.ATheApatient'sAtreatmentAshouldAbeAbasedAonAfunctionalAimpactAofAsymptomsAandAnotAfrequencyAofAsym
ptoms,AwhichAisAnotAindicatedAinAtheAquestion.ATheApatientAlikelyAhasAmoderateAacuteAtraveler'sAdiarrhea,A
whichAcanAbeAtreatedAwithAloperamideAasAmonotherapyAorAwithAadjunctiveAantibioticAtherapy.ATheApatient
AisAtakingAmetforminAdailyAforAdiabetes,AsoAriskAofAprecipitatingAhypoglycemiaAisAlowerAthanAwithAotherA
oralAantidiabeticAagents.ABecauseAitAcanAbeAgivenAinAaAsingleAdose,AciprofloxacinAwouldAbeAtheAappropriat
eAchoiceAforAreducingAexposureAandAmicrobiomeAcolonizationAdisruption.ALevofloxacinAandAofloxacinAre
quireAoneAtoAthreeAdoses.ATrimethoprim-
sulfamethoxazoleAisAaAsulfonamideAandAwouldAbeAappropriateAtreatmentAforAcyclosporiasisAbutAnotAgiardi
asis,AwhichAisAtheAmostAcommonAparasiticAcauseAofAtraveler'sAdiarrhea.
AApatientAnewlyAdiagnosedAwithAdiabetesAreportsAsevereAhivesAandAswollenAlipsAafterAtakingABactrimAforA
aAbladderAinfectionA2AmonthsAago.AWhichAofAtheAfollowingAstatementsAisAcorrect?
a.ATheApatientAcannotAtakeAanyApillsAinAtheAsulfonylureaAclass
b.ATheApatientAcanAtakeAsomeAofAtheApillsAinAtheAsulfonylureaAclass
c.ATheApatientAcanAtakeAanyAofAtheApillsAinAtheAsulfonylureaAclass
d.ANoneAofAtheAaboveA-AcorrectAanswer-c.ATheApatientAcanAtakeAanyAofAtheApillsAinAtheAsulfonylureaAclass
