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1. List all the factors that affect drug ab- Surface area of the body
sorption Rate of dissolution
Lipid solubility
Blood flow
Ion pH
2. List the following for Aminoglyco- Gentamycin, Neomycin, To-
sides bramycin
Examples of drug
MOA MOA: Inhibits protein synthesis spe-
Adverse Effects cific for 30 S Ribosome.
BBW
Adverse effects: nephrotoxicity,
ototoxicity, draw baseline renal func-
tion Measure peak and troughs
BBW: Caution with renal disease
3. List the following for Tetracycine Doxycycline(longer 1/2 life and less
Examples of drug GI effects) and tetracycline
MOA
Adverse Effects MOA: inhibit protein synthesis at 30
BBW S
Contraindications/interactions Adverse effects: discolors teeth in
children, PHOTOSENSITIVITY
BBW: Do not use in pregnancy or
breastfeeding or children under 8.
Contraindications/Interactions: do
not take with iron, calcium, and
magnesium. Antacids decrease ab-
sorption. Theophylline and warfarin
may increase or decrease drug ab-
sorption.
4. List the following for Fluroquinolones Levofloxacin, Ciprofloxacin
Examples of drug
MOA MOA: Inhibits DNA and RNA repli-
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Adverse Effects cation - bacterioidal
BBW
Adverse effects: PHOTOTOXICITY
BBW: Tendon rupture and myasthe-
nia gravis
5. List the following for Metronidazole Flagyl
Examples of drug
MOA MOA: antiparasitic
Adverse Effects
BBW Adverse effects: headache, nausea
BBW: DO NOT take with ETOH (72
hours) and avoi in first trimester
6. Which class of medications and Acute: Sumatriptan(All triptans) -
names are indicated in the manage- Imitrex
ment of acute migraine first line and NSAIDs
which are indicated for prophylaxis?
Prophylaxis: Beta Blockers (olols)
TCAs - amitriptyline
Anti-epileptics - Depakote
7. What drugs are indicated for treat- A.Bacterial vaginitis - Flagyl/Clin-
ment of the following types of vagini- damycin
tis
B. Candidiasis vaginitis - Moni-
stat(cream),
nystatin(cream), flucona-
zole(oral)/Diflucan (check liver en-
zymes for long term use
C. Atrophic vaginitis - intravaginal
hormone therapy (estradiol)
8. What is the class and mechanism of A. Aricept/Exelon: Cholinesterase
action of the following: inhibitors
A. Aricept/Exelon MOA: Reversible inhibition of
B. Namenda cholinesterase
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C. Mirapex
D. Carbidopa/Levidopa B. Namenda - N- Methyl-D-Aspar-
tate receptor antagonist
MOA: Regulates effect of glutamate
in post synaptic receptor
C. Mirapex: Dopamine Agonist: For
Parkinson's/restless leg syndrome
MOA: Binding of dopamine recep-
tors on nerve cells
D. Levodopa/Carbidopa: Dopamin-
ergic agents- helping replace
dopamine availability
9. List the types of progesterone only A. Nexplanon - implant in upper arm
contraceptives (SQ tissue)
B. Mirena - IUD
C. Depo-Provera - injection IM/SQ
D. mini pill
10. list the indications and contraindica- Indications:
tions of combined oral contraceptives A. Endometriosis
B. PCOS
C. Prevention of Pregnancy
D. dysmenorrhea
E. Irregular bleeding/cycle (cycle
regulation)
F. Acne
G. Pre menstrual migraines
H. PMS/PMDD
Contraindications:
A. History of breast cancer, 1st de-
gree relative
B. DVT/PE
C. Smoker over the age of 35
D. known pregnancy