Pharmacotherapeutics for Advanced Practice Nurse
Prescribers
1 - ✔✔-A 19-year-old male was started on risperidone. Monitoring for risperidone includes observing for
common side effects, including:
1. Bradykinesia, akathisia, and agitation
2. Excessive weight gain
3. Hypertension
4. Potentially fatal agranulocytosis
1 - ✔✔-A low-carbohydrate, high-protein diet may:
1. Increase drug-metabolizing enzymes
2. Decrease drug absorption from the GI tract
3. Alter drug binding to plasma proteins
4. Enhance drug elimination
1 - ✔✔-A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is
angioedema. Which of the following statements is true about this adverse response?
1. Swelling of the tongue or hoarseness are the most common symptoms.
2. It appears to be related to the decrease in aldosterone production.
3. Presence of a dry, hacky cough indicates a high risk for this adverse response.
4. Because it takes time to build up a blood level, it occurs after being on the drug for about 1 week.
1 - ✔✔-A stepwise approach to the pharmacologic management of asthma:
1. Begins with determining the severity of asthma and assessing asthma control
2. Is used when asthma is severe and requires daily steroids
3. Allows for each provider to determine their personal approach to the care of asthmatic patients
,4. Provides a framework for the management of severe asthmatics, but is not as helpful when patients have
intermittent asthma
1 - ✔✔-According to traditional Chinese medicine, if a person who has a fever is given a herb that is yang in
nature, such as golden seal, the patient's illness will:
1. Get worse
2. Get better
3. Not be adequately treated
4. Need additional herbs to treat the yan
1 - ✔✔-Age is a factor in different responses to pain. Which of the following age-related statements about pain
is NOT true?
1. Preterm and newborn infants do not yet have functional pain pathways.
2. Painful experiences and prolonged exposure to analgesic drugs during pregnancy may permanently alter
neuronal organization in the child.
3. Increases in the pain threshold in older adults may be related to peripheral neuropathies and changes in skin
thickness.
4. Decreases in pain tolerance are evident in older adults.
1 - ✔✔-All nonsteroidal anti-inflammatory drugs (NSAIDS) have an FDA Black Box Warning regarding:
1. Potential for causing life-threatening GI bleeds
2. Increased risk of developing systemic arthritis with prolonged use
3. Risk of life-threatening rashes, including Stevens-Johnson
4. Potential for transient changes in serum glucose
1 - ✔✔-Along with prescribing antibiotics, adults with pneumonia should be instructed on lifestyle modifications
to improve outcomes, including:
1. Adequate fluid intake
2. Increased fiber intake
,3. Bedrest for the first 24 hours
4. All of the above
1 - ✔✔-Alterations in drug metabolism among Asians may lead to:
1. Slower metabolism of antidepressants, requiring lower doses
2. Faster metabolism of neuroleptics, requiring higher doses
3. Altered metabolism of omeprazole, requiring higher doses
4. Slower metabolism of alcohol, requiring higher doses
1 - ✔✔-Anemia due to chronic renal failure is treated with:
1. Epoetin alfa (Epogen)
2. Ferrous sulfate
3. Vitamin B12
4. Hydroxyurea
1 - ✔✔-Asthma exacerbations at home are managed by the patient by:
1. Increasing frequency of beta-2-agonists and contacting their provider
2. Doubling inhaled corticosteroid doses
3. Increasing frequency of beta-2-agonists
4. Starting montelukast (Singulair)
1 - ✔✔-Because of its action on various body systems, the patient taking a thiazide or loop diuretic may also
need to receive the following supplement:
1. Potassium
2. Calcium
3. Magnesium
,4. Phosphates
1 - ✔✔-Because of the pattern of cholesterol synthesis, reductase inhibitors are given:
1. In the evening in a single daily dose
2. Twice daily in the morning and the evening
3. With each meal and at bedtime
4. In the morning before eating
1 - ✔✔-Because of their site of action, bile acid sequestering resins:
1. Should be administered separately from other drugs by at least 4 hours
2. May increase the risk for bleeding
3. Both 1 and 2
4. Neither 1 nor 2
1 - ✔✔-Beta blockers are especially helpful for patients with exertional angina who also have:
1. Arrhythmias
2. Hypothyroidism
3. Hyperlipidemia
4. Atherosclerosis
1 - ✔✔-Beta blockers treat hypertension because they:
1. Reduce peripheral resistance
2. Vasoconstrict coronary arteries
3. Reduce norepinephrine
4. Reduce angiotensin II production
1 - ✔✔-Bethanechol:
Prescribers
1 - ✔✔-A 19-year-old male was started on risperidone. Monitoring for risperidone includes observing for
common side effects, including:
1. Bradykinesia, akathisia, and agitation
2. Excessive weight gain
3. Hypertension
4. Potentially fatal agranulocytosis
1 - ✔✔-A low-carbohydrate, high-protein diet may:
1. Increase drug-metabolizing enzymes
2. Decrease drug absorption from the GI tract
3. Alter drug binding to plasma proteins
4. Enhance drug elimination
1 - ✔✔-A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is
angioedema. Which of the following statements is true about this adverse response?
1. Swelling of the tongue or hoarseness are the most common symptoms.
2. It appears to be related to the decrease in aldosterone production.
3. Presence of a dry, hacky cough indicates a high risk for this adverse response.
4. Because it takes time to build up a blood level, it occurs after being on the drug for about 1 week.
1 - ✔✔-A stepwise approach to the pharmacologic management of asthma:
1. Begins with determining the severity of asthma and assessing asthma control
2. Is used when asthma is severe and requires daily steroids
3. Allows for each provider to determine their personal approach to the care of asthmatic patients
,4. Provides a framework for the management of severe asthmatics, but is not as helpful when patients have
intermittent asthma
1 - ✔✔-According to traditional Chinese medicine, if a person who has a fever is given a herb that is yang in
nature, such as golden seal, the patient's illness will:
1. Get worse
2. Get better
3. Not be adequately treated
4. Need additional herbs to treat the yan
1 - ✔✔-Age is a factor in different responses to pain. Which of the following age-related statements about pain
is NOT true?
1. Preterm and newborn infants do not yet have functional pain pathways.
2. Painful experiences and prolonged exposure to analgesic drugs during pregnancy may permanently alter
neuronal organization in the child.
3. Increases in the pain threshold in older adults may be related to peripheral neuropathies and changes in skin
thickness.
4. Decreases in pain tolerance are evident in older adults.
1 - ✔✔-All nonsteroidal anti-inflammatory drugs (NSAIDS) have an FDA Black Box Warning regarding:
1. Potential for causing life-threatening GI bleeds
2. Increased risk of developing systemic arthritis with prolonged use
3. Risk of life-threatening rashes, including Stevens-Johnson
4. Potential for transient changes in serum glucose
1 - ✔✔-Along with prescribing antibiotics, adults with pneumonia should be instructed on lifestyle modifications
to improve outcomes, including:
1. Adequate fluid intake
2. Increased fiber intake
,3. Bedrest for the first 24 hours
4. All of the above
1 - ✔✔-Alterations in drug metabolism among Asians may lead to:
1. Slower metabolism of antidepressants, requiring lower doses
2. Faster metabolism of neuroleptics, requiring higher doses
3. Altered metabolism of omeprazole, requiring higher doses
4. Slower metabolism of alcohol, requiring higher doses
1 - ✔✔-Anemia due to chronic renal failure is treated with:
1. Epoetin alfa (Epogen)
2. Ferrous sulfate
3. Vitamin B12
4. Hydroxyurea
1 - ✔✔-Asthma exacerbations at home are managed by the patient by:
1. Increasing frequency of beta-2-agonists and contacting their provider
2. Doubling inhaled corticosteroid doses
3. Increasing frequency of beta-2-agonists
4. Starting montelukast (Singulair)
1 - ✔✔-Because of its action on various body systems, the patient taking a thiazide or loop diuretic may also
need to receive the following supplement:
1. Potassium
2. Calcium
3. Magnesium
,4. Phosphates
1 - ✔✔-Because of the pattern of cholesterol synthesis, reductase inhibitors are given:
1. In the evening in a single daily dose
2. Twice daily in the morning and the evening
3. With each meal and at bedtime
4. In the morning before eating
1 - ✔✔-Because of their site of action, bile acid sequestering resins:
1. Should be administered separately from other drugs by at least 4 hours
2. May increase the risk for bleeding
3. Both 1 and 2
4. Neither 1 nor 2
1 - ✔✔-Beta blockers are especially helpful for patients with exertional angina who also have:
1. Arrhythmias
2. Hypothyroidism
3. Hyperlipidemia
4. Atherosclerosis
1 - ✔✔-Beta blockers treat hypertension because they:
1. Reduce peripheral resistance
2. Vasoconstrict coronary arteries
3. Reduce norepinephrine
4. Reduce angiotensin II production
1 - ✔✔-Bethanechol:
