In the case of hypovitaminases D in an adult you would expect to see what?
Right Ans - Changes in the ratio of organic to inorganic constituents of bone
Osteitis fibrosa cystica is associated with what? Right Ans -
Hyperparathyroidism
What conditions are prone to pathologic fractures? Right Ans - -
Osteoporosis
- Paget's disease
- Infected bone
- Osteopetrosis
At what age is peak bone mass achieved? Right Ans - 32
What is the most important role of Vitamin C in intracellular collagen
synthesis? Right Ans - Maintaining iron atom on hydroxylating enzyme in
ferrous state
What is the most common cause of pathologic fracture? Right Ans -
Osteoporosis
Normal functioning osteoblasts and hypofunctioning osteoclasts are most
closely associated with what? Right Ans - Osteopetrosis
What category does "male with disproportionately short limb compared to
torso" belong to? Right Ans - Hereditary (genetic) condition
[Achondroplasia]
Developmentally for enchondral bone to go from cartilage structure to mature
bone what must be present? Right Ans - - Neovascularization
- Vitamin C
- Migration of fibroblasts into area
- Vitamin D
What are considered complications of fracture to the right femur? Right
Ans - - Osteoporosis
- Osteomyelitis
, - Cortical thickening of left femur
- Pseudoarthrosis
What is malabsorption from the gut related to? Right Ans - - Osteomalacia
- Ricketts
- Scurvy
- Osteoporosis
A patient with hyperparathyroidism could exhibit what? Right Ans - -
Osteitis fibrosa cystica
- Kidney stones
- Peptic ulcers
- Pathologic fractures
What condition does not affect the epiphyseal plate? Right Ans - Juvenile
paget's
If there is a problem with type 1 collagen; where is this this step a problem?
Right Ans - Defective procollagen peptidase
What are the 3 ways bone can become infected? Right Ans - - Direct
extension/seeding
- Open fracture
- Hematogenous spread
What is a Gibbous deformity? Right Ans - Sharply angled kyphosis
What is the benefit of having glycine at approximately every 3 amino acids?
Right Ans - Glycine is the smallest amino acid allowing a helix of collagen
chain to form
What might a sudden onset of pyogenic infection in bone marrow be
associated with? Right Ans - Trauma
Increased osteoblastic and osteoclastic activity as stimulated by mechanical
stress through bone describes what stage of fracture repair? Right Ans -
Early remodeling stage