Drug Action - Answers Specific and takes place at the molecular level. Or Substances interacting with the
CNS at the molecular level.
Drug Effect - Answers Non-specific and more highly variable, and result from more than a given dose of a
particular drug. The direct and indirect physical and psychic consequences of taking a specific drug.
Lethal Dose - Answers Quantity of a given drug that produces death in a designated group of subjects.
Effective Dose (Active Dose) - Answers Quantity of a given drug that produces a specific effect in a
percentage of a designated group of subjects.
ED/LD Ratio - Answers Size of the difference or gap between ED and LD, its safety margin or therapeutic
margin. Larger the ratio the safer the drug, vs. the smaller the ration the more dangerous.
Acute Effects - Answers With reference to drugs, the rapid or short-term effects of taking a given drug,
that is those that take place during a single episode of administration. Ex- Feeling high or buzzed.
Chronic Effects - Answers Drug effect that take place over a long period of time. Ex- Lung cancer from
smoking for 20 years.
Direct Effect - Answers Heavy drinking will damage the liver.
Indirect Effect - Answers Getting AIDS by using dirty needles.
Drug Fate - Answers The outcome of a process by which a given drug is broken down in the body and ,
eventually eliminated from the body.
Drug Mixing - Answers Taking two or more substances at the same time.
Purity - Answers The percentage of a given drug that a given sample contains.
Drug Tolerance - Answers Diminishing effects after repeated administration of a given drug.
Cross Tolerance - Answers Tolerance for one drug resulting in diminished effects of another drug.
Drug Dependence - Answers Compulsive repeated use of a substance whose basis is positive
reinforcement.
Dependence Reinforcement Model - Answers A drug does not have to be addicting in the sense of the
term (generating physical withdrawal symptoms) to produce a dependency in users, whether animal or
human.
Stimulants - Answers Category of drugs that produce a speeding up of signals passing through the CNS.
Ex- Cocaine, amphetamine and methamphetamine.
, Sedative-Hypnotics - Answers Inhibit and slow down signals passing through the CNS affecting wide
range of bodily functions. Ex- Alcohol, barbiturates, benzodiazepines.
Narcotics - Answers Act to depress or inhibit the perception of pain.
Depressants - Answers Substance that depresses a wide range of organ functions of the body.
Hallucinogen - Answers Category of drugs whose effects include profound sensory dislocation, referred
to as psychedelics. LSD and Mescaline.
Marijuana - Answers Dried buds and flowers of the cannabis plant.
Disassociative Anesthetics (PCP and Ketamine)- Classified as a hallucinogen.
Ectasy (MDMA) - Answers Hallucinogen
Route of Administration - Answers The way a given drug is taken, either orally, smoking, IV, trans-
dermal, Inhalation, etc.
Classic Addiction Model - Answers An Addicting drug is defined by the appearance of specific withdrawal
symptoms.
Lying - Answers It is the half truth that people will tell lies about their deviant, criminal, illegal, and
controversial behavior.
Sampling - Answers Systematically selecting a subset of a population that looks like or best represents
that population with respect to important characteristics.
Descriptive Statistics - Answers Describes what something is like in quantitative terms, form of numbers.
Basic numerical facts of life.
Inferential Statistics - Answers Attempt to measure cause and effect relationships between and among
two or more factors or variables.
Arrestee Drug Abuse Monitoring (ADAM II) - Answers Federally sponsored, ongoing data collection
program that drug tests and interviews arrestees in jails. Due to no legal consequences for testing
positive or admitting drug use, the response rate is very high.
Drug Abuse Warning Network (DAWN) - Answers Ongoing federally sponsored data collection program
that tabulates the number of drug related admissions to ED, as well as deaths by medical examiners.
Monitoring The Future (MTF) - Answers Ongoing federally sponsored, data collection program that
entails administering questionnaires on drug use to high school seniors, young adults not in college,
college students, and 8th and 10th graders.