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Test Bank Complete_ Adam's Pharmacology for Nurses: A Pathophysiologic Approach, 7th Edition, (2024) By Michael Adams, Norman Holland & Shanti Chang All Chapters 1-50| Nine Units| All Answers With Complete Explanations in all Choices

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Test Bank Complete_ Adam's Pharmacology for Nurses: A Pathophysiologic Approach, 7th Edition, (2024) By Michael Adams, Norman Holland & Shanti Chang All Chapters 1-50| Nine Units| All Answers With Complete Explanations in all Choices

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Test Bank Complete_ Adam's Pharmacology for Nurses:
A Pathophysiologic Approach, 7th Edition, (2024) By
Michael Adams, Norman Holland & Shanti Chang All
Chapters 1-50| Nine Units| All Answers With Complete
Explanations in all Choices
Pharmacology - ANSWERStudy of medicine; how drugs are administered; where
drugs travel in the body,
Response that drugs produce.

drug - ANSWERA chemical substance that is taken to cause changes in a person's
body or behavior

medication - ANSWERA substance that is used to treat or prevent disease or relieve
pain.

biologics - ANSWERagents naturally produced in animal cells, in microorganisms, or
by the body itself

Mechanism of Action - ANSWERhow a drug produces its physiological effect in the
body

Bioavailability - ANSWERthe extent to which the body can absorb and use a nutrient

Therapeutic classification of drugs: - ANSWERBased on what the drug does clinically

Pharmacologic Classification - ANSWERBased on the drug's mechanism of action, or
how the drug produces its effect

Most Drugs have three names - ANSWERChemical, Generic, Trade (CHEMICAL: (1/2)-
2-(p-isobutylphenyl) propionic acid; GENERIC: ibuprofen; TRADE: Motrin)

Generic vs. Trade-Name Drugs - ANSWERTrade name drugs with exclusive rights cost
more. When rights end, competing companies offer generic form cheaper

prescription drugs - ANSWERDrugs legally available only with a physician's order.

Over the counter drugs (OTC) - ANSWERcan be purchased without a prescription

Black Box Warnings - ANSWEROne of the primary alerts for identifying
extreme adverse drug reactions discovered
during and after the review
process; 1997 FDA created "Black Box Warnings"

Contraindications - ANSWERfactors that prevent the use of a drug or treatment

, why should healthcare professionals be concerned about patients taking herbal
medicines? - ANSWERpatients could be putting themselves at risk, potential herb-
drug interactions

U.S. Pharmacopoeia (USP) - ANSWER1820; 1st comprehensive publication formulary
used in the U.S.; drug purity, strength, and directions for synthesis.

USP and National Formulary (NF) - ANSWER1852-1975, two drug standards in the US
by the American Pharmaceutical Association (APhA). 1. USP - all drug products. 2.
National Formulary (NF) - pharmaceutical ingredients.

U.S. Pharacopoeia -National Formulary (USP-NF) - ANSWER1975 merged into a single
publication

Biologic Control Act - ANSWER1902 standardized serum and blood-related products

Pure Food and Drug Act - ANSWER1906 - Established government control (FDA) for
labeling
medicines

Shirley Amendment - ANSWER1912 - Prohibited drugs labeled with false therapeutic
claims

Food, Drug, and Cosmetic Act (1938) and amendments - ANSWER1938- Thorough
testing of drug; Proof of safety and efficacy of drug

Dietary Supplement Health and Education Act, 1994 - ANSWER1994-Controls
misleading industry claims

Four Stages of Approval for Therapeutic and Biologic Drugs - ANSWER1. Preclinical
investigation (1-3 years, average 18months)
2. Clinical investigation (2-10 years; average 5 years)
3. Review of new drug application (NDA) (2 months -7 years, average 24 months)
4. Postmarketing surveillance (adverse reaction reporting; surveys/sampling/testing;
inspections)

Addiction - ANSWERThe overwhelming feeling that drives someone to use a drug
repeated

Dependence - ANSWERA physiological or psychological need for a substance

Physical dependence - ANSWERAn altered physical condition caused by the
adaptation of the nervous system to repeated drug use.

Psychological dependence - ANSWERFew signs of physical discomfort when drug is
withdrawn, but intense compelling desire to continue drug use
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