Biochemistry ACS Final Exam Questions And Answers (Guaranteed A+)

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Biochemistry ACS Final Exam Questions
And Answers (Guaranteed A+)


What is the Henderson-Hasselbach ? - answer✔pH = pka + log ([A]/[Ha])

High Ka, low pka indicates what? - answer✔Strong acid

What is the relation between pH and [H+]? - answer✔pH = -log[H+]

What is the realtionship between pka and Ka? - answer✔pka = -logKa

What makes a good buffer? - answer✔A weak acid mixed with its conjugate base in a 50/50
ratio

What destroys tryptophan? - answer✔Acids and bases

What is the isoelectric point? - answer✔The pH in which a particular molecule carries no net
charge (pI)

Side chain pka of aspartic acid? - answer✔~ 3.86

Side chain pka of arginine? - answer✔~ 12.48

Side chain pka of cysteine? - answer✔~8.0

Side chain pka of glutamic acid? - answer✔~4.07

Side chain pka of histidine? - answer✔~6.1

Side chain pka of lysine? - answer✔~10.53

Side chain pka of tyrosine? - answer✔~10.00

Inductive effect on pka? - answer✔Electronegative atoms pull electrons away from another
group, and makes that particular groups more positive. Generally lowers pka

Electrostatic effect on pka? - answer✔Nearby positive charge makes a proton want to leave
more, generally lowers pka.

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