LUPUS NCLEX PRACTICE QUESTIONS
WITH COMPLETE ANSWERS
The ffnurse ffis ffpreparing ffa ffpresentation ffon ffsystemic fflupus fferythematosus ff(SLE).
ffWhich ffstatement ffshould ffthe ffnurse ffinclude? ff(Select ffall ffthat ffapply.)
A. ffThe ffetiology ffis ffknown ffto ffbe fflinked ffto ffenvironmental fffactors.
B. ffManifestations ffcan ffbe ffmild ffto fffatal, ffwith ffremissions ffand ffexacerbations.
C. ffThe ffimmune ffcomplex ffdeposits fftrigger ffan ffinflammatory ffresponse.
D. ffSLE ffis ffa ffresult ffof ffdeposition ffof ffantigen-antibody ffcomplexes ffin ffconnective
fftissues.
E. ffThe ffinflammatory ffresponse ffleads ffto ffanaphylactic ffshock. ff- ffAnswer ffB.
ffManifestations ffcan ffbe ffmild ffto fffatal, ffwith ffremissions ffand ffexacerbations.
C. ffThe ffimmune ffcomplex ffdeposits fftrigger ffan ffinflammatory ffresponse.
D. ffSLE ffis ffa ffresult ffof ffdeposition ffof ffantigen-antibody ffcomplexes ffin ffconnective
fftissues.
The ffpathophysiology ffof ffsystemic fflupus fferythematosus ffis ffa ffresult ffof ffthe ffformation
ffof ff
antigen-antibody ffimmunocomplexes ffthat ffare ffdeposited ffin ffthe ffconnective fftissue
ffand fftrigger ffan ffinflammatory ffresponse. ffThe ffmanifestations ffof ffthe ffdisease ffcan ffbe
ffmild ffto fffatal, ffand ffremissions ffare fffollowed ffby ffexacerbations. ffThe ffinflammatory
ffresponse ffleads ffto fftissue ffdamage ffbut ffnot ffanaphylactic ffshock ff(allergic ffreaction).
ffAlthough ffthe ffexact ffetiology ffof ffSLE ffis ffunknown, ffgenetic, ffethnic, ffenvironmental,
ffand ffhormonal fffactors ffplay ffa ffrole ffin ffits ffdevelopment.
The ffnurse ffis ffassessing ffa ffclient ffwith ffsystemic fflupus fferythematosus ff(SLE). ffWhich
ffclinical ffmanifestation ffshould ffthe ffnurse ffexpect ffto ffobserve? ff(Select ffall ffthat ffapply.)
A. ffRed ffbutterfly ffrash ffon ffthe ffface
B. ffAlopecia
C. ffPsoriatic fflesions
D. ffPainful ffor ffswollen ffjoints
E. ffLeg ffand ffeye ffedema ff- ffAnswer ffA. ffRed ffbutterfly ffrash ffon ffthe ffface
B. ffAlopecia
D. ffPainful ffor ffswollen ffjoints
E. ffLeg ffand ffeye ffedema
Rationale: ffPainful ffswollen ffjoints, ffalopecia, ffred ffbutterfly ffrash ffon ffthe ffface, ffand ffleg
ffand ffeye ffedema ffare ffall ffcharacteristics ffof ffSLE. ffPsoriatic fflesions ffare ffcaused ffby
, ffpsoriasis, ffwhich ffis ffan ffautoimmune ffdisease ffcharacterized ffby ffpatches ffof
ffabnormal ffskin.
The ffnurse ffis ffassessing ffa ffclient ffwith ffsystemic fflupus fferythematosus ff(SLE). ffWhich
ffmanifestation ffshould ffthe ffnurse ffrecognize ffas ffa ffresult ffof ffinflammation? ff(Select ffall
ffthat ffapply.)
A. ffCough
B. ffMalaise
C. ffMaculopapular ffrash
D. ffJoint ffpain
E.Fever ff- ffAnswer ffB. ffMalaise
C. ffMaculopapular ffrash
D. ffJoint ffpain
E. ffFever
In ffSLE, ffthe ffimmunocomplexes ffthat ffare ffdeposited ffin ffthe ffconnective fftissue fftrigger
ffan ffinflammatory ffresponse. ffJoint ffpain, fffever, ffmalaise, ffand ffmaculopapular ffrash
ffare ffall ffsigns ffof ffthe ffinflammation ffthat ffresult fffrom fflocal fftissue ffdamage. ffA ffcough
ffis ffa ffsign ffof ffinfection, ffnot ffof ffinflammation ffresulting fffrom fftissue ffdamage.
A ffclient ffdiagnosed ffwith ffsystemic fflupus fferythematosus ff(SLE) ffis ffexperiencing
ffpulmonary ffinterstitial fffibrosis. ffWhich ffclassification ffof fflupus ffshould ffthe ffnurse
ffsuspect?
A. ffSystemic
B. ffDrug-induced
C. ffDiscoid
D. ffCutaneous ff- ffAnswer ffA. ffSystemic
The ffclassification ffof fflupus ffthe ffclient ffis ffexperiencing ffis ffsystemic. ffThere ffare ffthree
ffmajor ffclassifications ffof ffSLE: ffdiscoid ffor ffcutaneous, ffsystemic, ffand ffdrug-induced.
ffSystemic fflupus ffinvolves ffone ffor ffmore ffof ffthese ffsystems: ffcardiovascular, ffcentral
ffnervous, ffhematologic, ffkidneys, fflungs, ffand ffmusculoskeletal. ffCutaneous ffor ffdiscoid
fflupus ffis fflimited ffto ffthe ffskin. ffMany ffdrugs ffcan ffcause ffa ffsyndrome ffthat ffmimics
fflupus ff(drug-induced fflupus).
The ffnurse ffis ffcaring fffor ffa ffclient ffwith ffsystemic fflupus fferythematosus ff(SLE). ffWhich
ffsystem ffshould ffthe ffnurse ffconsider ffas ffbeing ffmost ffaffected ffby ffthe ffformation ffof
ffimmune ffcomplexes ffand fftissue ffdamage?
A. ffCardiac
B. ffIntegumentary
C. ffRespiratory
D. ffRenal ff- ffAnswer ffD. ffRenal
WITH COMPLETE ANSWERS
The ffnurse ffis ffpreparing ffa ffpresentation ffon ffsystemic fflupus fferythematosus ff(SLE).
ffWhich ffstatement ffshould ffthe ffnurse ffinclude? ff(Select ffall ffthat ffapply.)
A. ffThe ffetiology ffis ffknown ffto ffbe fflinked ffto ffenvironmental fffactors.
B. ffManifestations ffcan ffbe ffmild ffto fffatal, ffwith ffremissions ffand ffexacerbations.
C. ffThe ffimmune ffcomplex ffdeposits fftrigger ffan ffinflammatory ffresponse.
D. ffSLE ffis ffa ffresult ffof ffdeposition ffof ffantigen-antibody ffcomplexes ffin ffconnective
fftissues.
E. ffThe ffinflammatory ffresponse ffleads ffto ffanaphylactic ffshock. ff- ffAnswer ffB.
ffManifestations ffcan ffbe ffmild ffto fffatal, ffwith ffremissions ffand ffexacerbations.
C. ffThe ffimmune ffcomplex ffdeposits fftrigger ffan ffinflammatory ffresponse.
D. ffSLE ffis ffa ffresult ffof ffdeposition ffof ffantigen-antibody ffcomplexes ffin ffconnective
fftissues.
The ffpathophysiology ffof ffsystemic fflupus fferythematosus ffis ffa ffresult ffof ffthe ffformation
ffof ff
antigen-antibody ffimmunocomplexes ffthat ffare ffdeposited ffin ffthe ffconnective fftissue
ffand fftrigger ffan ffinflammatory ffresponse. ffThe ffmanifestations ffof ffthe ffdisease ffcan ffbe
ffmild ffto fffatal, ffand ffremissions ffare fffollowed ffby ffexacerbations. ffThe ffinflammatory
ffresponse ffleads ffto fftissue ffdamage ffbut ffnot ffanaphylactic ffshock ff(allergic ffreaction).
ffAlthough ffthe ffexact ffetiology ffof ffSLE ffis ffunknown, ffgenetic, ffethnic, ffenvironmental,
ffand ffhormonal fffactors ffplay ffa ffrole ffin ffits ffdevelopment.
The ffnurse ffis ffassessing ffa ffclient ffwith ffsystemic fflupus fferythematosus ff(SLE). ffWhich
ffclinical ffmanifestation ffshould ffthe ffnurse ffexpect ffto ffobserve? ff(Select ffall ffthat ffapply.)
A. ffRed ffbutterfly ffrash ffon ffthe ffface
B. ffAlopecia
C. ffPsoriatic fflesions
D. ffPainful ffor ffswollen ffjoints
E. ffLeg ffand ffeye ffedema ff- ffAnswer ffA. ffRed ffbutterfly ffrash ffon ffthe ffface
B. ffAlopecia
D. ffPainful ffor ffswollen ffjoints
E. ffLeg ffand ffeye ffedema
Rationale: ffPainful ffswollen ffjoints, ffalopecia, ffred ffbutterfly ffrash ffon ffthe ffface, ffand ffleg
ffand ffeye ffedema ffare ffall ffcharacteristics ffof ffSLE. ffPsoriatic fflesions ffare ffcaused ffby
, ffpsoriasis, ffwhich ffis ffan ffautoimmune ffdisease ffcharacterized ffby ffpatches ffof
ffabnormal ffskin.
The ffnurse ffis ffassessing ffa ffclient ffwith ffsystemic fflupus fferythematosus ff(SLE). ffWhich
ffmanifestation ffshould ffthe ffnurse ffrecognize ffas ffa ffresult ffof ffinflammation? ff(Select ffall
ffthat ffapply.)
A. ffCough
B. ffMalaise
C. ffMaculopapular ffrash
D. ffJoint ffpain
E.Fever ff- ffAnswer ffB. ffMalaise
C. ffMaculopapular ffrash
D. ffJoint ffpain
E. ffFever
In ffSLE, ffthe ffimmunocomplexes ffthat ffare ffdeposited ffin ffthe ffconnective fftissue fftrigger
ffan ffinflammatory ffresponse. ffJoint ffpain, fffever, ffmalaise, ffand ffmaculopapular ffrash
ffare ffall ffsigns ffof ffthe ffinflammation ffthat ffresult fffrom fflocal fftissue ffdamage. ffA ffcough
ffis ffa ffsign ffof ffinfection, ffnot ffof ffinflammation ffresulting fffrom fftissue ffdamage.
A ffclient ffdiagnosed ffwith ffsystemic fflupus fferythematosus ff(SLE) ffis ffexperiencing
ffpulmonary ffinterstitial fffibrosis. ffWhich ffclassification ffof fflupus ffshould ffthe ffnurse
ffsuspect?
A. ffSystemic
B. ffDrug-induced
C. ffDiscoid
D. ffCutaneous ff- ffAnswer ffA. ffSystemic
The ffclassification ffof fflupus ffthe ffclient ffis ffexperiencing ffis ffsystemic. ffThere ffare ffthree
ffmajor ffclassifications ffof ffSLE: ffdiscoid ffor ffcutaneous, ffsystemic, ffand ffdrug-induced.
ffSystemic fflupus ffinvolves ffone ffor ffmore ffof ffthese ffsystems: ffcardiovascular, ffcentral
ffnervous, ffhematologic, ffkidneys, fflungs, ffand ffmusculoskeletal. ffCutaneous ffor ffdiscoid
fflupus ffis fflimited ffto ffthe ffskin. ffMany ffdrugs ffcan ffcause ffa ffsyndrome ffthat ffmimics
fflupus ff(drug-induced fflupus).
The ffnurse ffis ffcaring fffor ffa ffclient ffwith ffsystemic fflupus fferythematosus ff(SLE). ffWhich
ffsystem ffshould ffthe ffnurse ffconsider ffas ffbeing ffmost ffaffected ffby ffthe ffformation ffof
ffimmune ffcomplexes ffand fftissue ffdamage?
A. ffCardiac
B. ffIntegumentary
C. ffRespiratory
D. ffRenal ff- ffAnswer ffD. ffRenal
