BIOD322 NEUROSCIENCE
Module 8
LATEST FINAL TEST REVIEW
Q&S
©2024/2025
,1. Which neurotransmitter is primarily involved in the
pathophysiology of Parkinson's Disease?
A) Dopamine
B) Serotonin
C) Glutamate
D) GABA
Correct Answer: A) Dopamine
Rationale: Dopamine is a neurotransmitter that plays a
significant role in the motor control and emotional responses. In
Parkinson's Disease, the dopaminergic neurons in the substantia
nigra part of the brain are progressively lost, leading to the
characteristic symptoms of the disease.
2. Multiple Sclerosis is characterized by which type of immune
response?
A) Humoral immunity
B) Cell-mediated immunity
C) Innate immunity
D) Both A and B
Correct Answer: D) Both A and B
Rationale: Multiple Sclerosis is an autoimmune disorder where
both the humoral and cell-mediated immune responses are
©2024/2025
,involved. The body's immune system attacks the myelin sheath of
nerve fibers, causing inflammation and consequent nerve damage.
3. What is the hallmark pathological finding in Alzheimer's
Disease?
A) Lewy bodies
B) Neurofibrillary tangles
C) Spongiform changes
D) Amyloid plaques
Correct Answer: D) Amyloid plaques
Rationale: Amyloid plaques, composed of beta-amyloid peptide,
are the characteristic pathological feature of Alzheimer's Disease.
These extracellular deposits are found in the brains of patients and
are associated with neurodegeneration.
4. In the context of epilepsy, what does the term 'kindling' refer
to?
A) The process of initiating a seizure by electrical stimulation
B) A spontaneous remission of seizure activity
C) The development of resistance to antiepileptic drugs
D) The genetic predisposition to seizure disorders
Correct Answer: A) The process of initiating a seizure by
electrical stimulation
©2024/2025
, Rationale: Kindling is a phenomenon where repeated
subconvulsive stimuli lead to the development of spontaneous
seizures. It is a model used to study the development and
treatment of epilepsy.
5. Which area of the brain is primarily affected in Huntington's
Disease?
A) Frontal lobe
B) Cerebellum
C) Basal ganglia
D) Hippocampus
Correct Answer: C) Basal ganglia
Rationale: Huntington's Disease is a genetic disorder that
primarily affects the basal ganglia, which are involved in
movement control. The disease leads to motor dysfunction,
cognitive decline, and psychiatric symptoms.
6. The Blood-Brain Barrier (BBB) can be compromised in which
neurological condition?
A) Migraine
B) Stroke
C) Guillain-Barré syndrome
D) Myasthenia Gravis
©2024/2025
Module 8
LATEST FINAL TEST REVIEW
Q&S
©2024/2025
,1. Which neurotransmitter is primarily involved in the
pathophysiology of Parkinson's Disease?
A) Dopamine
B) Serotonin
C) Glutamate
D) GABA
Correct Answer: A) Dopamine
Rationale: Dopamine is a neurotransmitter that plays a
significant role in the motor control and emotional responses. In
Parkinson's Disease, the dopaminergic neurons in the substantia
nigra part of the brain are progressively lost, leading to the
characteristic symptoms of the disease.
2. Multiple Sclerosis is characterized by which type of immune
response?
A) Humoral immunity
B) Cell-mediated immunity
C) Innate immunity
D) Both A and B
Correct Answer: D) Both A and B
Rationale: Multiple Sclerosis is an autoimmune disorder where
both the humoral and cell-mediated immune responses are
©2024/2025
,involved. The body's immune system attacks the myelin sheath of
nerve fibers, causing inflammation and consequent nerve damage.
3. What is the hallmark pathological finding in Alzheimer's
Disease?
A) Lewy bodies
B) Neurofibrillary tangles
C) Spongiform changes
D) Amyloid plaques
Correct Answer: D) Amyloid plaques
Rationale: Amyloid plaques, composed of beta-amyloid peptide,
are the characteristic pathological feature of Alzheimer's Disease.
These extracellular deposits are found in the brains of patients and
are associated with neurodegeneration.
4. In the context of epilepsy, what does the term 'kindling' refer
to?
A) The process of initiating a seizure by electrical stimulation
B) A spontaneous remission of seizure activity
C) The development of resistance to antiepileptic drugs
D) The genetic predisposition to seizure disorders
Correct Answer: A) The process of initiating a seizure by
electrical stimulation
©2024/2025
, Rationale: Kindling is a phenomenon where repeated
subconvulsive stimuli lead to the development of spontaneous
seizures. It is a model used to study the development and
treatment of epilepsy.
5. Which area of the brain is primarily affected in Huntington's
Disease?
A) Frontal lobe
B) Cerebellum
C) Basal ganglia
D) Hippocampus
Correct Answer: C) Basal ganglia
Rationale: Huntington's Disease is a genetic disorder that
primarily affects the basal ganglia, which are involved in
movement control. The disease leads to motor dysfunction,
cognitive decline, and psychiatric symptoms.
6. The Blood-Brain Barrier (BBB) can be compromised in which
neurological condition?
A) Migraine
B) Stroke
C) Guillain-Barré syndrome
D) Myasthenia Gravis
©2024/2025
