MCPHS Microbiology Self Paced Exam II
Questions and Answers
The patient's fever spikes each evening. Oxidase-positive, gram-negative coccobacilli were
isolated from a lesion on his arm. What is your diagnosis? Correct Ans-brucellosis
The removal of plasmids reduces virulence in which of the following organisms? Correct
Ans-strep mutans
The toxin neutralization assay __________. Correct Ans-can detect the presence of antitoxin
The viral hemagglutination inhibition test __________. Correct Ans-can be used to detect the
presence of antibody to the measles virus in patient serum
This microbe is acquired by humans as infants and is essential for good health. Correct Ans-e
coli
this pneumonia etiology requires cell culture Correct Ans-chlamydophilia
To detect the presence of antibody to a pathogen in a person through use of the indirect
fluorescent-antibody technique, __________. Correct Ans-a known antigen is fixed to a slide,
patient serum is added, and labeled antibodies that are directed against human antibodies are
added
,To perform an indirect ELISA test to identify the strain of influenza in a patient, you would mix
the following ingredients. Which do you add FIRST? Correct Ans-antigen
Toxin Correct Ans-substance that contributes to pathogenicity
Toxoid Correct Ans-inactivated toxin used in a vaccine
trachoma Correct Ans-blindness, scar cornea, inturned eyelids
transient microbiota Correct Ans-may be present for days, weeks, or months
transmission Correct Ans-contact
-indirect: fomile: nonliving object
droplets
Vehicle
food, water, air, blood
Vector
mechanical: passive carries pathogen on feet
biological: pathogen reproduces in vector
,typhus Correct Ans-caused by louse
undulent fever Correct Ans-Brucella species
Universal Precautions Correct Ans-standatd
transmission based: contact, droplet, airborne
Viral vaccines Correct Ans-Flu
mmr attenuated humoral cellular
varicella
polio killed humoral
rabies
hep a
hep b ag fraction humoral
smallpox
herpes
hpv
Viral vaccines are more potent than bacterial Correct Ans-Just humoral is weak and needs
booster
Virulence Correct Ans-the extent of pathogenicity
, what bacteria are a beta hemolytic Correct Ans-strep pyogenes
what bacteria are identified by a positive coagulase test Correct Ans-staph aureus
What is the method of action of nucleoside analogs? Correct Ans-inhibit dna synthesis
Which antifungal drug was recently introduced to treat systemic fungal infections? Correct
Ans-posaconazole
Which antimicrobial works by inhibiting the synthesis of mycolic acid? Correct Ans-
isoniazid
which leads to the rest Correct Ans-tracheal cytotoxin
Which of the following does not represent the same mechanism for avoiding host defenses as the
others Correct Ans-surface protein genes in n. gonorrhea mutate frequently
Which of the following is NOT a mechanism by which antibiotic resistance spreads horizontally
among bacteria? Correct Ans-bacterial transcription
Which of the following is not a notifiable disease Correct Ans-pneumonia
Questions and Answers
The patient's fever spikes each evening. Oxidase-positive, gram-negative coccobacilli were
isolated from a lesion on his arm. What is your diagnosis? Correct Ans-brucellosis
The removal of plasmids reduces virulence in which of the following organisms? Correct
Ans-strep mutans
The toxin neutralization assay __________. Correct Ans-can detect the presence of antitoxin
The viral hemagglutination inhibition test __________. Correct Ans-can be used to detect the
presence of antibody to the measles virus in patient serum
This microbe is acquired by humans as infants and is essential for good health. Correct Ans-e
coli
this pneumonia etiology requires cell culture Correct Ans-chlamydophilia
To detect the presence of antibody to a pathogen in a person through use of the indirect
fluorescent-antibody technique, __________. Correct Ans-a known antigen is fixed to a slide,
patient serum is added, and labeled antibodies that are directed against human antibodies are
added
,To perform an indirect ELISA test to identify the strain of influenza in a patient, you would mix
the following ingredients. Which do you add FIRST? Correct Ans-antigen
Toxin Correct Ans-substance that contributes to pathogenicity
Toxoid Correct Ans-inactivated toxin used in a vaccine
trachoma Correct Ans-blindness, scar cornea, inturned eyelids
transient microbiota Correct Ans-may be present for days, weeks, or months
transmission Correct Ans-contact
-indirect: fomile: nonliving object
droplets
Vehicle
food, water, air, blood
Vector
mechanical: passive carries pathogen on feet
biological: pathogen reproduces in vector
,typhus Correct Ans-caused by louse
undulent fever Correct Ans-Brucella species
Universal Precautions Correct Ans-standatd
transmission based: contact, droplet, airborne
Viral vaccines Correct Ans-Flu
mmr attenuated humoral cellular
varicella
polio killed humoral
rabies
hep a
hep b ag fraction humoral
smallpox
herpes
hpv
Viral vaccines are more potent than bacterial Correct Ans-Just humoral is weak and needs
booster
Virulence Correct Ans-the extent of pathogenicity
, what bacteria are a beta hemolytic Correct Ans-strep pyogenes
what bacteria are identified by a positive coagulase test Correct Ans-staph aureus
What is the method of action of nucleoside analogs? Correct Ans-inhibit dna synthesis
Which antifungal drug was recently introduced to treat systemic fungal infections? Correct
Ans-posaconazole
Which antimicrobial works by inhibiting the synthesis of mycolic acid? Correct Ans-
isoniazid
which leads to the rest Correct Ans-tracheal cytotoxin
Which of the following does not represent the same mechanism for avoiding host defenses as the
others Correct Ans-surface protein genes in n. gonorrhea mutate frequently
Which of the following is NOT a mechanism by which antibiotic resistance spreads horizontally
among bacteria? Correct Ans-bacterial transcription
Which of the following is not a notifiable disease Correct Ans-pneumonia
