PHCL 412 Antidepressants Exam Study Guide

PHCL 412 Antidepressants Exam
Study Guide
Depression is caused by what? - Answer Deficiency in...

- Catecholamines(2)

- Indoleamines(1)

Catecholamines deficient in depression - Answer dopamine;DA and norepinephrine;NE

indoleamine neurotransmitter deficient in depression - Answer serotonin ;5HT

SSRIs/SNRIs are examples of ____ drugs. - Answer Newer

Tricyclics are examples of ____ drugs. - Answer Older

ALL tricyclics block the re-uptake of both ______ and ______, WITH EFFECTS on a
number of other receptors. - Answer NE

5-HT

What are some symptoms of TCAs (Tricyclic Antidepressants)? - Answer ( jst saw ap )

JITTERY

SEDATION

TACHYCARDIA

SEXUAL DISFUNCTION

ANTIMUSCARINIC

WEIGHT GAIN

ARRHYTHMIA

POSTURAL HYPOTENSION

MAOIs (monoamine oxidase inhibitors) _________ metabolism of neurotransmitters. -
Answer Prevent

MAOIs cause an _______ of synaptic levels of neurotransmitters. - Answer Elevation

SSRIs block _______ re-uptake. - Answer 5-HT

What are some side effects of SSRIs? - Answer GI disturbance