ASCP Hematology- Erythropoiesis Exam Questions and Correct Answers (Rated 100%)

ASCP Hematology- Erythropoiesis Exam Questions and Correct Answers (Rated 100%) What is erythropoiesis? - Answers red blood cell formation, production, and destruction what is the maturation process of erythrocytes? - Answers give rise to progenitors burst forming unit erythroid (BFU-E) colony forming unit erythroid (CFU-E) how many RBCs result from division of 1 pronormoblast - Answers 8-32 mature RBCs characteristics of pronormoblast - Answers nucleus takes up most of nucleus:cytoplasm ratio 8:1 round/oval dark blue cytoplasm (ribosomes) ONLY IN BONE MARROW Basophilic normoblast - Answers 2nd stage of erythroid progenitors chromatin condenses N:C of 6:1 deeper, richer blue stage lasts ~24 hours hemoglobin synthesis ONLY IN BONE MARROW what do basophilic normoblasts give rise to - Answers 2 daughter cells polychromic normoblast - Answers 3rd stage of erythroid progenitors N:C of 4:1 or 1:1 no nuclei pink color from stained hemoglobin increase in hemoglobin synthesis cellular organelles present stage lasts ~30 hours ONLY IN BONE MARROW orthochromic normoblast - Answers N:C ratio of 1:2 salmon-pink color cytoplasm showing nearly complete hgb production hemoglobin production continues on ribosomes using mRNA stage lasts ~48 hours