GI PRACTICE QUESTIONS AND 100% CORRECT
ANSWERS 2025-2026
Where in the GI tract is lipids broken down?
A. Esophagus
B. Stomach
C. Small intestine
D. Large intestine - ANSWER B
Marvin, a known alcoholic with cirrhosis is in frequently for coagulopathies and
occasionally requires blood transfusions. His wife asks you why he has a bleeding
problem. You respond:
A. Occasionally he accumulates blood in the gut.
B. There is an interruption of normal clotting mechanisms.
C. Long term alcohol abuse has made his vessels very friable.
D. His bone marrow has been affected. - ANSWER B
Jonas, age 34 years, had a Billroth II (hemigastrectomy and gastrojejunostomy) 1 week
ago and has just started to eat a bland diet. What do you suspect when he tells you that
he experiences epigastric fullness, distention, discomfort, abdominal cramping, nausea,
and flatus after eating?
A. Obstruction
B. Dumping syndrome
C. Metabolic acidosis
D. Infectious colitis - ANSWER B
A relatively common complication of viral gastroenteritis in children is:
,A. Dehydration
B. GI bleeding
C. Peritonitis
D Bacterial sepsis - ANSWER A
The most important diagnostic test for celiac disease is:
A. Confirming malabsorption by lab tests
B. Barium enema
C. A peroral biopsy of the duodenum
D. A gluten free diet trial with an accompanying improvement in mucosal histological
response - ANSWER D
What is the most common cause of melena?
A. Colon cancer
B. Upper GI bleeding
C. Drug abuse
D. Smoking - ANSWER B
Which of the following maneuvers for diagnosing appendicitis is done by deep palpation
over the LLQ with resultant pain in the RLQ?
A. Rovsing's sign
B. Psoas sign
C. Obturator sign
D. McBurney's sign - ANSWER A
,Sam has UC and is on a low residue diet. Which foods would you recommend Sam
avoid?
A. Potato skins, potato chips, and brown rice
B. Vegetable juices and cooked and canned vegetables
C. Ground beef, veal, pork and lamb
D. White rice and pasta - ANSWER A
Which of the following treatments for UC is contraindicated?
A. A high calorie, nonspicy, caffeine free diet that is low in high residue foods and milk
products
B. Corticosteroids in the acute phase
C. Antidiarrheal agents
D. Colectomy with permanent ileostomy in severe cases - ANSWER C
Olive has an acute exacerbation of Crohn's disease. Which lab test values would you
expect to be decreased?
A. ESR
B. LFT
C. Vitamin A, B complex, and C levels
D. Bilirubin - ANSWER C
You suspect Harry has a peptic ulcer and tell him that it has been found to be strongly
associated with:
A. anxiety and panic attacks
, B. long term NSAID use
C. infection with H. pylori
D. a family history of peptic ulcer - ANSWER C
You are doing routine teaching with a patient who has a family history of colorectal
cancer. You know she misunderstands the teaching when she tells you:
A. decrease her fat intake
B. increase her fiber intake
C. continue her daily ASA use
D. increase her fluid intake - ANSWER D
The proper order of assessment of the abdomen is:
A. palpation, percussion, auscultation, inspection
B. inspection, palpation, auscultation, percussion
C. inspection, auscultation, percussion, palpation
D. percussion, auscultation, inspection, palpation - ANSWER C
Which of the following antibiotics causes more episodes of nausea and/or vomiting than
the others?
A. Azithromycin
B. Erythromycin
C. Penicillin
D. Tetracycline - ANSWER B
Melva presents with an exacerbation of acute pancreatitis and you are going to admit
ANSWERS 2025-2026
Where in the GI tract is lipids broken down?
A. Esophagus
B. Stomach
C. Small intestine
D. Large intestine - ANSWER B
Marvin, a known alcoholic with cirrhosis is in frequently for coagulopathies and
occasionally requires blood transfusions. His wife asks you why he has a bleeding
problem. You respond:
A. Occasionally he accumulates blood in the gut.
B. There is an interruption of normal clotting mechanisms.
C. Long term alcohol abuse has made his vessels very friable.
D. His bone marrow has been affected. - ANSWER B
Jonas, age 34 years, had a Billroth II (hemigastrectomy and gastrojejunostomy) 1 week
ago and has just started to eat a bland diet. What do you suspect when he tells you that
he experiences epigastric fullness, distention, discomfort, abdominal cramping, nausea,
and flatus after eating?
A. Obstruction
B. Dumping syndrome
C. Metabolic acidosis
D. Infectious colitis - ANSWER B
A relatively common complication of viral gastroenteritis in children is:
,A. Dehydration
B. GI bleeding
C. Peritonitis
D Bacterial sepsis - ANSWER A
The most important diagnostic test for celiac disease is:
A. Confirming malabsorption by lab tests
B. Barium enema
C. A peroral biopsy of the duodenum
D. A gluten free diet trial with an accompanying improvement in mucosal histological
response - ANSWER D
What is the most common cause of melena?
A. Colon cancer
B. Upper GI bleeding
C. Drug abuse
D. Smoking - ANSWER B
Which of the following maneuvers for diagnosing appendicitis is done by deep palpation
over the LLQ with resultant pain in the RLQ?
A. Rovsing's sign
B. Psoas sign
C. Obturator sign
D. McBurney's sign - ANSWER A
,Sam has UC and is on a low residue diet. Which foods would you recommend Sam
avoid?
A. Potato skins, potato chips, and brown rice
B. Vegetable juices and cooked and canned vegetables
C. Ground beef, veal, pork and lamb
D. White rice and pasta - ANSWER A
Which of the following treatments for UC is contraindicated?
A. A high calorie, nonspicy, caffeine free diet that is low in high residue foods and milk
products
B. Corticosteroids in the acute phase
C. Antidiarrheal agents
D. Colectomy with permanent ileostomy in severe cases - ANSWER C
Olive has an acute exacerbation of Crohn's disease. Which lab test values would you
expect to be decreased?
A. ESR
B. LFT
C. Vitamin A, B complex, and C levels
D. Bilirubin - ANSWER C
You suspect Harry has a peptic ulcer and tell him that it has been found to be strongly
associated with:
A. anxiety and panic attacks
, B. long term NSAID use
C. infection with H. pylori
D. a family history of peptic ulcer - ANSWER C
You are doing routine teaching with a patient who has a family history of colorectal
cancer. You know she misunderstands the teaching when she tells you:
A. decrease her fat intake
B. increase her fiber intake
C. continue her daily ASA use
D. increase her fluid intake - ANSWER D
The proper order of assessment of the abdomen is:
A. palpation, percussion, auscultation, inspection
B. inspection, palpation, auscultation, percussion
C. inspection, auscultation, percussion, palpation
D. percussion, auscultation, inspection, palpation - ANSWER C
Which of the following antibiotics causes more episodes of nausea and/or vomiting than
the others?
A. Azithromycin
B. Erythromycin
C. Penicillin
D. Tetracycline - ANSWER B
Melva presents with an exacerbation of acute pancreatitis and you are going to admit
