HEMATOLOGY EXAM 4 QUESTIONS
WITH COMPLETE ANSWERS
Neutrophils jjthat jjroll jjacross jjthe jjendothelium jjlooking jjfor jjtrouble jjare jjin jjthe jj_____
jjpool. jj- jjAnswer jjmarginating
The jjterm jj____ jjrefers jjto jjthe jjmovement jjof jjthe jjneutrophil jjbetween jjendothelial jjcells.
jj- jjAnswer jjdiapedesis
Foreign jjcells jjthat jjhave jjbeen jjcoated jjwith jjIgG1 jj& jj3, jjand jjC3b jj& jjC3bi jjare jjtermed:
jj- jjAnswer jjopsonized
Which jjdoes jjnot jjrefer jjto jjthe jjoxygen jjdependent jjkilling jjof jjmicroorganisms?
>the jjrespiratory jjburst
>production jjof jjH2O2
>production jjof jjcomplement
>production jjof jjsuperoxide jj- jjAnswer jjproduction jjof jjcomplement
During jjphagocytosis, jjthe jjmaterial jjis jjdegraded jjin jjthe jj______. jj- jjAnswer
jjphagolysosome
Which jjenzyme jjfrom jjthe jjprimary jjgranules jjis jjinvolved jjin jjthe jjrespiratory jjburst? jj-
jjAnswer jjmyeloperoxidase
Which jjenzyme jjfrom jjthe jjsecondary jjgranules jjis jjinvolved jjin jjthe jjrespiratory jjburst? jj-
jjAnswer jjNADPH jjoxidase
The jjenzyme jj_____ jjcombines jjH2O2 jjwith jjCl jjto jjproduce jjhypochlorite. jj- jjAnswer
jjmyeloperoxidase
Mutation jjin jj____ jjwill jjresult jjin jjchronic jjgranulomatous jjdisease. jj- jjAnswer jjNADH
jjoxidase
What jjis jjthe jjreference jjrange jjfor jjneutrophils jjin jjadults? jj- jjAnswer jj1.8-7.0 jjx jj10^9/L
Which jjcell jjis jjmost jjsimilar jjto jjmast jjcells? jj- jjAnswer jjbasophils
Which jjcell jjis jjelevated jjin jjasthma, jjhives, jjand jjworms? jj- jjAnswer jjeosinophils
,The jjdefect jjin jjchronic jjgranulomatous jjdisease jjis jjattributed jjto: jj- jjAnswer jjdefective
jjbacterial jjkilling
A jjdecrease jjin jjneutrophils jjbelow jj1.5 jjx jj10^9/L jjis: jj- jjAnswer jjneutropenia
Which jjof jjthe jjfollowing jjis jjtrue jjabout jjthis jjcell?
>It jjhas jj2 jjX jjchromosomes
>It's jjowner jjis jjmale
>It's jja jjband
>It's jjfound jjin jjchronic jjgranulomatous jjdisease jj- jjAnswer jj>It jjhas jj2 jjX jjchromosomes
Which jjof jjthese jjwould jjbe jjthe jjmost jjlikely jjto jjcause jjneutrophilia, jjgiving jja jjrange
jjbetween jj10-25 jjx jj1^9/L? jj- jjAnswer jjstaphylococcus jjinfection
Which jjof jjthe jjfollowing jjis jjnot jjassociated jjwith jja jjleukemoid jjreaction?
>BCR/ABL jjmutation
>increased jjLAP
>Total jjWBC jj< jj50 jjx jj10^9/L
>Dohle jjbodies jjand jjvacuoles jjin jjsegmented jjneutrophils jj- jjAnswer jjBCR/ABL jjmutation
Is jjthis jjleukemia jjor jjleukemoid?
32 jjyear jjold jjpatient jjpresented jjwith jjWBC jjof jj32.5 jjx jj10^9/L. jjDiff jjwas jj70% jjsegs,
jj15% jjbands, jj5% jjmetamyelocytes, jj8% jjlymphocytes, jjand jj2% jjmonocytes. jjLAP jjwas
jj150. jj- jjAnswer jjleukemoid
Is jjthis jjleukemia jjor jjleukemoid?
72 jjyear jjold jjpatient jjpresented jjwith jjWBC jjof jj32.5 jjx jj10^9/L. jjDiff jjwas jj30% jjsegs,
jj15% jjbands, jj25% jjmetamyelocytes, jj10% jjmyelocytes, jj2% jjpromyelocytes, jj8%
jjlymphocytes. jjLAP jjwas jj11. jj- jjAnswer jjleukemia
Large jjDohle-like jjinclusions jjand jjgiant jjplatelets: jj- jjAnswer jjMay jjHegglin
Increased jjmucopolysaccharides jjare jjseen jjin jjall jjof jjthese jjexcept: jj- jjAnswer jjMay
jjHegglin
Large jjlysosomes jjin jjWBC jjthat jjare jjineffective jjat jjkilling: jj- jjAnswer jjchediak jjhigashi
Prince jjnez jjbenign jjcondition: jj- jjAnswer jjPelger jjHuet
An jjadult jjpatient's jjtotal jjleukocyte jjcount jjis jj5.0 jjx jj10^9/L. jjThere jjare jj60% jjsegmented
jjneutrophils, jj35% jjlymphocytes jjand jj5% jjmonocytes jjon jjthe jjdifferential. jjCalculate jjthe
jjabsolute jjnumber jjof jjgranulocytes jjto jjanswer jjthe jjquestion. jj
,Which jjis jjnormal? jj- jjAnswer jjthe jjgranulocyte jjabsolute jjnumber jjand jjpercent jj(are
jjnormal)
For jjthe jjabsolute jjcounts, jjyou jjshould jjhave jjcalculated:
Neutrophils: jj3.0 jjx jj109/L
Lymphocytes: jj1.64 jjx jj109/L
Monocytes: jj0.25 jjx jj109/L
The jjhallmark jjof jjdifferentiating jjmyelocytes jjfrom jjpromyelocytes jjmorphologically jjis
jjthe jjvisual jjidentification jjof jjwhat jjin jjthe jjmyelocytes? jj- jjAnswer jjsecondary jjgranules
In jjthe jjneutrophil jjmaturation jjseries, jjprimary jjgranules jjfirst jjappear jjin jjwhat jjimmature
jjcell? jj- jjAnswer jjpromyelocyte
The jjeosinophil's jjprimary jjfunction jjis jjto: jj- jjAnswer jjprotect jjthe jjhost jjfrom jjhelminth
jjparasites
Basophil's jjand jjmast jjcells jjhave jjreceptors jjfor jjwhich jjimmunoglobulin? jj- jjAnswer jjIgE
The jjtotal jjWBC jjcount jjfor jjan jjadult jjis jj13.1 jjx jj10^9/L jjwith jja jjdifferential jjcount jjthat
jjreveals jj20% jjeosinophils. jjThis jjrepresents jja: jj- jjAnswer jjrelative jjand jjabsolute
jjeosinophilia
Which jjof jjthe jjfollowing jjhematological jjvalues jjwould jjyou jjexpect jjif jjthe jjperipheral
jjblood jjsmear jjrevealed jjtoxic jjgranulation, jjdohle jjbodies, jjand jjvacuoles jjin jjneutrophils?
jj- jjAnswer jjthe jjdifferential jjshows jj15% jjbands
Which jjof jjthe jjfollowing jjcan jjbe jjused jjto jjdistinguish jja jjleukemoid jjreaction jjfrom jjCML?
jj- jjAnswer jjLAP jjscore
Which jjof jjthe jjfollowing jjcan jjcauses jjtoxic jjgranulation jjof jjneutrophils? jj
Select jjAll jjThat jjApply. jj
>bacterial jjinfection
>burns
>severe jjinflammation
>pernicious jjanemia jj- jjAnswer jjbacterial jjinfections
burns
severe jjinflammation
True jjor jjFalse: jjWhen jjtesting jjwith jjNBT jj(nitroblue jjtetrazolium jjslide jjtests), jjpatients
jjwith jjCGD jjwill jjshow jja jjrobust jjaccumulation jjof jjdark jjcrystals jjin jjtheir jjneutrophils. jj-
jjAnswer jjfalse
In jjthe jjneutrophilic jjmaturation jjseries, jjthe jjcell: jj_______ jjis jjthe jjlast jjstage jjcapable jjof
jjmitotic jjactivity. jj- jjAnswer jjmyelocyte
, 72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
Given jjAgnes's jjlaboratory jjresults, jjwould jjthis jjmost jjlikely jjbe jjconsidered jjan jjacute jjor
jjchronic jjleukemia? jj- jjAnswer jjchronic-the jjWBC jjare jjmature
72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
What jjgroup jjof jjleukemia jj(cell jjlineage) jjis jjsuggested jjby jjthe jjpatient's jjblood jjcell
jjdifferential jjresults? jj- jjAnswer jjlymphocyte
72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
What jjwould jjyou jjexpect jjthe jjblast jjcount jjin jjthe jjbone jjmarrow jjto jjbe? jj- jjAnswer
jj<20%
72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
Would jjyou jjexpect jjAgnes jjto jjsurvive jjmore jjthan jj3 jjyears, jjor jjsuccumb jjfairly jjquickly
jjafter jjtreatment? jj- jjAnswer jjsurvive jjmore jjthan jj3 jjyears
WITH COMPLETE ANSWERS
Neutrophils jjthat jjroll jjacross jjthe jjendothelium jjlooking jjfor jjtrouble jjare jjin jjthe jj_____
jjpool. jj- jjAnswer jjmarginating
The jjterm jj____ jjrefers jjto jjthe jjmovement jjof jjthe jjneutrophil jjbetween jjendothelial jjcells.
jj- jjAnswer jjdiapedesis
Foreign jjcells jjthat jjhave jjbeen jjcoated jjwith jjIgG1 jj& jj3, jjand jjC3b jj& jjC3bi jjare jjtermed:
jj- jjAnswer jjopsonized
Which jjdoes jjnot jjrefer jjto jjthe jjoxygen jjdependent jjkilling jjof jjmicroorganisms?
>the jjrespiratory jjburst
>production jjof jjH2O2
>production jjof jjcomplement
>production jjof jjsuperoxide jj- jjAnswer jjproduction jjof jjcomplement
During jjphagocytosis, jjthe jjmaterial jjis jjdegraded jjin jjthe jj______. jj- jjAnswer
jjphagolysosome
Which jjenzyme jjfrom jjthe jjprimary jjgranules jjis jjinvolved jjin jjthe jjrespiratory jjburst? jj-
jjAnswer jjmyeloperoxidase
Which jjenzyme jjfrom jjthe jjsecondary jjgranules jjis jjinvolved jjin jjthe jjrespiratory jjburst? jj-
jjAnswer jjNADPH jjoxidase
The jjenzyme jj_____ jjcombines jjH2O2 jjwith jjCl jjto jjproduce jjhypochlorite. jj- jjAnswer
jjmyeloperoxidase
Mutation jjin jj____ jjwill jjresult jjin jjchronic jjgranulomatous jjdisease. jj- jjAnswer jjNADH
jjoxidase
What jjis jjthe jjreference jjrange jjfor jjneutrophils jjin jjadults? jj- jjAnswer jj1.8-7.0 jjx jj10^9/L
Which jjcell jjis jjmost jjsimilar jjto jjmast jjcells? jj- jjAnswer jjbasophils
Which jjcell jjis jjelevated jjin jjasthma, jjhives, jjand jjworms? jj- jjAnswer jjeosinophils
,The jjdefect jjin jjchronic jjgranulomatous jjdisease jjis jjattributed jjto: jj- jjAnswer jjdefective
jjbacterial jjkilling
A jjdecrease jjin jjneutrophils jjbelow jj1.5 jjx jj10^9/L jjis: jj- jjAnswer jjneutropenia
Which jjof jjthe jjfollowing jjis jjtrue jjabout jjthis jjcell?
>It jjhas jj2 jjX jjchromosomes
>It's jjowner jjis jjmale
>It's jja jjband
>It's jjfound jjin jjchronic jjgranulomatous jjdisease jj- jjAnswer jj>It jjhas jj2 jjX jjchromosomes
Which jjof jjthese jjwould jjbe jjthe jjmost jjlikely jjto jjcause jjneutrophilia, jjgiving jja jjrange
jjbetween jj10-25 jjx jj1^9/L? jj- jjAnswer jjstaphylococcus jjinfection
Which jjof jjthe jjfollowing jjis jjnot jjassociated jjwith jja jjleukemoid jjreaction?
>BCR/ABL jjmutation
>increased jjLAP
>Total jjWBC jj< jj50 jjx jj10^9/L
>Dohle jjbodies jjand jjvacuoles jjin jjsegmented jjneutrophils jj- jjAnswer jjBCR/ABL jjmutation
Is jjthis jjleukemia jjor jjleukemoid?
32 jjyear jjold jjpatient jjpresented jjwith jjWBC jjof jj32.5 jjx jj10^9/L. jjDiff jjwas jj70% jjsegs,
jj15% jjbands, jj5% jjmetamyelocytes, jj8% jjlymphocytes, jjand jj2% jjmonocytes. jjLAP jjwas
jj150. jj- jjAnswer jjleukemoid
Is jjthis jjleukemia jjor jjleukemoid?
72 jjyear jjold jjpatient jjpresented jjwith jjWBC jjof jj32.5 jjx jj10^9/L. jjDiff jjwas jj30% jjsegs,
jj15% jjbands, jj25% jjmetamyelocytes, jj10% jjmyelocytes, jj2% jjpromyelocytes, jj8%
jjlymphocytes. jjLAP jjwas jj11. jj- jjAnswer jjleukemia
Large jjDohle-like jjinclusions jjand jjgiant jjplatelets: jj- jjAnswer jjMay jjHegglin
Increased jjmucopolysaccharides jjare jjseen jjin jjall jjof jjthese jjexcept: jj- jjAnswer jjMay
jjHegglin
Large jjlysosomes jjin jjWBC jjthat jjare jjineffective jjat jjkilling: jj- jjAnswer jjchediak jjhigashi
Prince jjnez jjbenign jjcondition: jj- jjAnswer jjPelger jjHuet
An jjadult jjpatient's jjtotal jjleukocyte jjcount jjis jj5.0 jjx jj10^9/L. jjThere jjare jj60% jjsegmented
jjneutrophils, jj35% jjlymphocytes jjand jj5% jjmonocytes jjon jjthe jjdifferential. jjCalculate jjthe
jjabsolute jjnumber jjof jjgranulocytes jjto jjanswer jjthe jjquestion. jj
,Which jjis jjnormal? jj- jjAnswer jjthe jjgranulocyte jjabsolute jjnumber jjand jjpercent jj(are
jjnormal)
For jjthe jjabsolute jjcounts, jjyou jjshould jjhave jjcalculated:
Neutrophils: jj3.0 jjx jj109/L
Lymphocytes: jj1.64 jjx jj109/L
Monocytes: jj0.25 jjx jj109/L
The jjhallmark jjof jjdifferentiating jjmyelocytes jjfrom jjpromyelocytes jjmorphologically jjis
jjthe jjvisual jjidentification jjof jjwhat jjin jjthe jjmyelocytes? jj- jjAnswer jjsecondary jjgranules
In jjthe jjneutrophil jjmaturation jjseries, jjprimary jjgranules jjfirst jjappear jjin jjwhat jjimmature
jjcell? jj- jjAnswer jjpromyelocyte
The jjeosinophil's jjprimary jjfunction jjis jjto: jj- jjAnswer jjprotect jjthe jjhost jjfrom jjhelminth
jjparasites
Basophil's jjand jjmast jjcells jjhave jjreceptors jjfor jjwhich jjimmunoglobulin? jj- jjAnswer jjIgE
The jjtotal jjWBC jjcount jjfor jjan jjadult jjis jj13.1 jjx jj10^9/L jjwith jja jjdifferential jjcount jjthat
jjreveals jj20% jjeosinophils. jjThis jjrepresents jja: jj- jjAnswer jjrelative jjand jjabsolute
jjeosinophilia
Which jjof jjthe jjfollowing jjhematological jjvalues jjwould jjyou jjexpect jjif jjthe jjperipheral
jjblood jjsmear jjrevealed jjtoxic jjgranulation, jjdohle jjbodies, jjand jjvacuoles jjin jjneutrophils?
jj- jjAnswer jjthe jjdifferential jjshows jj15% jjbands
Which jjof jjthe jjfollowing jjcan jjbe jjused jjto jjdistinguish jja jjleukemoid jjreaction jjfrom jjCML?
jj- jjAnswer jjLAP jjscore
Which jjof jjthe jjfollowing jjcan jjcauses jjtoxic jjgranulation jjof jjneutrophils? jj
Select jjAll jjThat jjApply. jj
>bacterial jjinfection
>burns
>severe jjinflammation
>pernicious jjanemia jj- jjAnswer jjbacterial jjinfections
burns
severe jjinflammation
True jjor jjFalse: jjWhen jjtesting jjwith jjNBT jj(nitroblue jjtetrazolium jjslide jjtests), jjpatients
jjwith jjCGD jjwill jjshow jja jjrobust jjaccumulation jjof jjdark jjcrystals jjin jjtheir jjneutrophils. jj-
jjAnswer jjfalse
In jjthe jjneutrophilic jjmaturation jjseries, jjthe jjcell: jj_______ jjis jjthe jjlast jjstage jjcapable jjof
jjmitotic jjactivity. jj- jjAnswer jjmyelocyte
, 72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
Given jjAgnes's jjlaboratory jjresults, jjwould jjthis jjmost jjlikely jjbe jjconsidered jjan jjacute jjor
jjchronic jjleukemia? jj- jjAnswer jjchronic-the jjWBC jjare jjmature
72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
What jjgroup jjof jjleukemia jj(cell jjlineage) jjis jjsuggested jjby jjthe jjpatient's jjblood jjcell
jjdifferential jjresults? jj- jjAnswer jjlymphocyte
72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
What jjwould jjyou jjexpect jjthe jjblast jjcount jjin jjthe jjbone jjmarrow jjto jjbe? jj- jjAnswer
jj<20%
72 jjyear jjold jjfemale, jjAgnes. jjPersistent jjcough jjand jjfatigue, jjhad jjalways jjbeen jjin
jjgood jjhealth; jjupon jjexamination-pale, jjslight jjsplenomegaly. jj
WBC jj83.9 jjx jj10^9/L
RBC jj3.15 jjx jj10^9/L
Hb jj9.5g/dL jj(95g/L)
Hct jj29% jj(0.29L/L)
Platelets jj130 jjx jj10^9/L
Would jjyou jjexpect jjAgnes jjto jjsurvive jjmore jjthan jj3 jjyears, jjor jjsuccumb jjfairly jjquickly
jjafter jjtreatment? jj- jjAnswer jjsurvive jjmore jjthan jj3 jjyears
