NNP Exam Questions and Answers
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Which of the following would provide the weakest evidence for practice?
A.
Case study
B.
Case-control study
C.
Quasi-experimental study - ✔✔A.
Level Evidence type I meta-analysis and/or systematic review of
randomized-controlled trials (RCT); II single RCT; III quasi-experiment
(non-randomized); IV non-experimental study (case-control, cohort,
correlational); V systematic reviews of descriptive studies or qualitative
studies; VI single qualitative study or cross-section study (survey); VII
expert opinion, case reports, committee reports (Polit & Beck, 2018, pp. 23-
34; Thomas, 2015, p. 840).
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An initial sign of hyperkalemia on an EKG is
A.
Peaked T waves
B.
Slurring of the QRS
C.
Ventricular fibrillation - ✔✔A.
EKG changes are often the first sign of hyperkalemia. EKG findings are
altered as the serum K + rises, presenting with varying levels of peaked T
waves (secondary to increased repolarization of the cardiac tissue),
flattened P waves, and increased PR intervals (secondary to suppression
of atrial conductivity). These changes are followed by widening and slurring
of the QRS complex (secondary to delay in ventricular conduction as well
as delays in myocardial conduction) with eventual development of
supraventricular tachycardia, ventricular tachycardia, bradycardia, or
ventricular fibrillation (Doherty, 2017, p. 308).
The Henderson-Hasselebalch equation is a negative logarithm that
calculates the level of
A.
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Bicarbonate ions
B.
Dioxide ions
C.
Hydrogen ions - ✔✔C.
The Henderson-Hasselebalch equation calculates plasma pH. The pH is a
negative logarithm that measures the level of hydrogen ions (H+), which
means that there is an inverse relationship between the pH and H+. The
pH decreases with a rise in H+ and increases with a fall in H+. The pH
remains normal when there is a balance in changes of carbon dioxide
(CO2) and bicarbonate (HCO3) (Barry, Deacon, Hernandez, & Jones,
2016, p. 145).
The neonatal nurse practitioner (NNP) knows that a serum peak level of a
drug is generally reflective of the infants:
A.
Excretion of metabolites
B.
Digestion of the drug
C.
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Volume of distribution
answer - ✔✔C.
Volume of distribution (Vd) is influenced by gestational age due to the rapid
changes in total body water and fluid shifts (Allegaert et al., 2018, p. 428;
Wade, 2015, p. 666).
Infants with large extracellular fluid volumes have increased Vd for water-
soluble drugs and may reduce peak drug values and affect drug excretion
(Blackburn, 2018, p. 198).
Decreased body fat in preterm and intrauterine growth-restricted infants
decreases the Vd for lipophilic drugs (Blackburn, 2018, p. 199).
Pharmacokinetics is the process of drug
A.
Absorption, distribution, biotransformation, and excretion
B.
Adaptations made to physiological systems by the drugs
C.
Alterations, metabolism, and excretion in the cellular matrix - ✔✔A.