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BMS 602 Mycobacterium Tuberculosis
Exam Questions and Answers 100%
Solved
describe Mycobacterium spp. - ✔✔non motile, non spore forming, aerobic
rods, neither gram negative or positive, generally slow growers in vitro
describe Mycobacterium spp. cell wall - ✔✔very hydrophobic,
peptidoglycan layer linked to arabinogalactan, mycolic acid layer overlaid
with lipis, glycolipids, peptidoglycolipids and proteins
what was tuberculosis also know as? - ✔✔great white plague
M. tuberculosis pathogen - ✔✔acid fast, slow growing, rod
M. tuberculosis encounter - ✔✔human reservoir (humans are natural
reservoir)
M. tuberculosis entry - ✔✔human to human spread via inhalation of
contaminated respiratory secretions from infected individual
M. tuberculosis spread - ✔✔spread from site infection via tissue destruction
and lymph system
, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
M. tuberculosis multiplication - ✔✔colonizes alveolar macrophages,
replicating in specialized vacuole or in cytosol
M. tuberculosis damage - ✔✔infection may elicit immune response which
controls infection of an immune response that destroys lung tissue
M. tuberculosis diagnosis - ✔✔culture and microscopy culture sputum,
tuberculin skin test, IFN gamma release test
describe primary infection of M. tuberculosis - ✔✔begins when
contaminated droplets reach alveoli of the lung,, binds to macrophage and
is engulfed by alveolar macrophages but hasn't been activated by a CD4 T
cell therefore cannot digest M. tuberculosis, M. tuberculosis establishes
replicative vacuole, replicates inside macrophage for 7-21 days, destroys
macrophage, recruits macrophages T cell, natural killer cell and dendritic
cells to site of infection, dendritic cells process antigen and present antigen
to MHC I and MHC II proteins
what do CD8 cells with a TCR that recognizes M. tuberulosis antigen do? -
✔✔lyse infected macrophages and dendritic cells, release IFn gamma
which activated macrophages
what do CD4 cells with a TCR that recognizes M. tuberulosis antigen do? -
✔✔differentiate into Th2 and Th1 cells, Th1 release IFN gamma which
BMS 602 Mycobacterium Tuberculosis
Exam Questions and Answers 100%
Solved
describe Mycobacterium spp. - ✔✔non motile, non spore forming, aerobic
rods, neither gram negative or positive, generally slow growers in vitro
describe Mycobacterium spp. cell wall - ✔✔very hydrophobic,
peptidoglycan layer linked to arabinogalactan, mycolic acid layer overlaid
with lipis, glycolipids, peptidoglycolipids and proteins
what was tuberculosis also know as? - ✔✔great white plague
M. tuberculosis pathogen - ✔✔acid fast, slow growing, rod
M. tuberculosis encounter - ✔✔human reservoir (humans are natural
reservoir)
M. tuberculosis entry - ✔✔human to human spread via inhalation of
contaminated respiratory secretions from infected individual
M. tuberculosis spread - ✔✔spread from site infection via tissue destruction
and lymph system
, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
M. tuberculosis multiplication - ✔✔colonizes alveolar macrophages,
replicating in specialized vacuole or in cytosol
M. tuberculosis damage - ✔✔infection may elicit immune response which
controls infection of an immune response that destroys lung tissue
M. tuberculosis diagnosis - ✔✔culture and microscopy culture sputum,
tuberculin skin test, IFN gamma release test
describe primary infection of M. tuberculosis - ✔✔begins when
contaminated droplets reach alveoli of the lung,, binds to macrophage and
is engulfed by alveolar macrophages but hasn't been activated by a CD4 T
cell therefore cannot digest M. tuberculosis, M. tuberculosis establishes
replicative vacuole, replicates inside macrophage for 7-21 days, destroys
macrophage, recruits macrophages T cell, natural killer cell and dendritic
cells to site of infection, dendritic cells process antigen and present antigen
to MHC I and MHC II proteins
what do CD8 cells with a TCR that recognizes M. tuberulosis antigen do? -
✔✔lyse infected macrophages and dendritic cells, release IFn gamma
which activated macrophages
what do CD4 cells with a TCR that recognizes M. tuberulosis antigen do? -
✔✔differentiate into Th2 and Th1 cells, Th1 release IFN gamma which
