NSCI 175- exam 1 (poll EV + quiz
questions)
What level of analysis is studying the prefrontal cortex and amygdala in nicotine addiction? - Answer-
systems
What level of analysis is studying the properties of the nicotinic acetylcholine receptor? - Answer-
molecular
What are we measuring when we measure the resting membrane potential? - Answer-the electrical
potential of the inside of the cell with respect to the outside of the cell
Given the concentration gradients discussed, if a K+ ion channel opened, which direction would K+ ions
move based on diffusion? - Answer-out of the cell (efflux)
Membrane is only permeable to K+. The internal solution contains 100mM KCL, while the external
solution has 10 mM KCL. What is the equilibrium potential (Ek)? - Answer--61.5 mV
If you increase extracellular K+ and the cell is permeable to K+, what does this do to the membrane
potential? - Answer-depolarize the cell
, How sensitive is the trans-membrane potential across cells to small changes in extracellular sodium? -
Answer-not very sensitive
Why do we need the Goldman equation? Why can't we just use the Nernst equation to calculate resting
membrane potential? - Answer-the neuronal membrane is permeable to more than one ion
What happens when you increase the permeability of the cell to sodium? - Answer-the membrane
potential depolarizes (towards ENa)
If you initiated the action potential in the middle of the axon, which direction would the action potential
travel? - Answer-both directions
If you were to block Na+ channels with a drug, what would happen to the action potentials? - Answer-
block action potentials
Which ion is absolutely required for neurotransmitter release? - Answer-Ca2+
You've discovered a drug that seems to bind to the cannabinoid receptor and prevent endogenous
cannabinoids from binding. What kind of drug is it? - Answer-antagonist
Which cortical area shows properties of temporal summation? - Answer-somatosensory cortex
Activating the beta adrenergic receptor results in CLOSING of the K+ channel--what would this do to the
length constant? - Answer-increase
Where would you look in the brain for ACh neurons? - Answer-basal forebrain and striatum
If your GABAergic neurons lost function/died, what would happen? - Answer-you would have seizures
questions)
What level of analysis is studying the prefrontal cortex and amygdala in nicotine addiction? - Answer-
systems
What level of analysis is studying the properties of the nicotinic acetylcholine receptor? - Answer-
molecular
What are we measuring when we measure the resting membrane potential? - Answer-the electrical
potential of the inside of the cell with respect to the outside of the cell
Given the concentration gradients discussed, if a K+ ion channel opened, which direction would K+ ions
move based on diffusion? - Answer-out of the cell (efflux)
Membrane is only permeable to K+. The internal solution contains 100mM KCL, while the external
solution has 10 mM KCL. What is the equilibrium potential (Ek)? - Answer--61.5 mV
If you increase extracellular K+ and the cell is permeable to K+, what does this do to the membrane
potential? - Answer-depolarize the cell
, How sensitive is the trans-membrane potential across cells to small changes in extracellular sodium? -
Answer-not very sensitive
Why do we need the Goldman equation? Why can't we just use the Nernst equation to calculate resting
membrane potential? - Answer-the neuronal membrane is permeable to more than one ion
What happens when you increase the permeability of the cell to sodium? - Answer-the membrane
potential depolarizes (towards ENa)
If you initiated the action potential in the middle of the axon, which direction would the action potential
travel? - Answer-both directions
If you were to block Na+ channels with a drug, what would happen to the action potentials? - Answer-
block action potentials
Which ion is absolutely required for neurotransmitter release? - Answer-Ca2+
You've discovered a drug that seems to bind to the cannabinoid receptor and prevent endogenous
cannabinoids from binding. What kind of drug is it? - Answer-antagonist
Which cortical area shows properties of temporal summation? - Answer-somatosensory cortex
Activating the beta adrenergic receptor results in CLOSING of the K+ channel--what would this do to the
length constant? - Answer-increase
Where would you look in the brain for ACh neurons? - Answer-basal forebrain and striatum
If your GABAergic neurons lost function/died, what would happen? - Answer-you would have seizures
