TESTBANK FOR PHARMACOLOGY ILLUSTRATED REVIEWS 8TH EDITION WHALEN TEST BANK

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TESTBANK FOR PHARMACOLOGY ILLUSTRATED
REVIEWS 8TH EDITION WHALEN TEST BANK

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CH: 1: Pharmacokinetics

MULTIPLE CHOICE

1. Which medicine s will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral analgesics
d. Subcutaneous antiglycemics
RIGHT ANS:-C
EXPLAN :->>>When medicine s are administered parenterally, there is no pharmaceutic phase,
which occurs when a medicine becomes a solution that can cross the biologic membrane.

DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

2. The professional medical caretaker is preparing to administer an oral medicine and
wants to ensure a rapid medicine action. Which form of the medicine will the professional
medical caretaker administer?
a. Capsule
b. Enteric-coated pill
c. Liquid suspension
d. Tablet
ANS: C
EXPLAN :->>>Liquid medicine s are already in solution, which is the form necessary for
absorption in the GI tract.The other forms must disintegrate into small particles and then
dissolve before being absorbed.

DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies




Page 1 of 507

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3. The professional medical caretaker is teaching a hospital patient who will be discharged home
with a prescription for an enteric-coated tablet. Which statement by the hospital patient indicates
understanding of the teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medicine.
c. I should expect a delay in onset of the medicine s effects after taking the tablet.
d. I should take this medicine with high-fat foods to improve its action.
RIGHT ANS:-C
EXPLAN:->>>Enteric-coated tablets resist disintegration in the acidic environment of the
stomach and disintegrate when they reach the small intestine. There is usually some delay in
onset of actionsafter taking these medicines. Enteric-coated tablets should not be crushed or
chewed, which would alter the time and location of absorption. Acidic foods will not enhance
the absorption ofthe medicine. The hospital patient should not to eat high-fat food before
ingesting an enteric-coated tablet, because high-fat foods decrease the absorption rate.

DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

4. A hospital patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin
must be given by subcutaneous injection instead of by mouth. The professional medical
caretaker will explain that this is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects.
RIGHT ANS:-C
EXPLAN:->>>Insulin, growth hormones, and other protein-based medicine s are destroyed in
the small intestine bydigestive enzymes and must be given parenterally. Because insulin is
destroyed by digestive enzymes, it would not make it to the liver for metabolism with a first-
pass effect. Subcutaneoustissue has fewer blood vessels, so absorption is slower in such tissue.
Insulin is given subcutaneously because it is desirable to have it absorb slowly.

DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention: Hospital patient
Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

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Page 2 of 507




5. The professional medical caretaker is preparing to administer an oral medicine that is
water-soluble. The professional medical caretaker understands that this medicine
a. must be taken on an empty stomach.
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestinal tract.
RIGHT ANS:-B
EXPLAN:->>>Water-soluble medicine s require a carrier enzyme or protein to pass through the GI
membrane.

DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

6. A professional medical caretaker is preparing to administer an oral medicine that is best
absorbed in an acidic environment. How will the professional medical caretaker give the
medicine ?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food
RIGHT ANS:-C
Food can stimulate the production of gastric acid so medicines requiring an acidic environment
should be given with a meal. High-fat foods are useful for medicine s that are lipid soluble.

DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies

7. The professional medical caretaker is preparing an injectable medicine and wants to
administer it for rapid absorption. Howwill the professional medical caretaker give this
medicine?
a. IM into the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper arm
RIGHT ANS:-A